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Cancer incidence in a cohort of Finnish male smokers.
Eur J Cancer Prev. 2006 Apr; 15(2):103-7.EJ

Abstract

A total of 29,133 male smokers, aged 50-69 years, were recruited into the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study in 1984-1988. The nationwide Finnish Cancer Registry (FCR) recorded 5944 incident cases of cancer in this cohort through the end of 1999. Compared with the FCR data of the entire Finnish male population of same age the standardized incidence ratio (SIR) of total cancer in the ATBC cohort was 1.55 [95% confidence interval (CI) 1.51-1.59]. There was a significant excess of established smoking-related malignancies, such as lung cancer (SIR 2.45, 95% CI 2.35-2.56), and cancers of the tongue, mouth, pharynx, larynx, oesophagus, pancreas, stomach, liver, urinary bladder and kidney. In addition to these sites, cancers of the prostate and colon were slightly more common in the ATBC cohort than in the total Finnish male population (SIR 1.10, 95% CI 1.04-1.18 and SIR 1.14, 95% CI 1.00-1.30, respectively). In conclusion, the risk of many cancers was significantly higher in the ATBC Study cohort compared with the total Finnish male population of same age. In addition to the well known smoking-related cancers, cigarette smoking may increase slightly the risk of colon and prostate cancer, too.

Authors+Show Affiliations

Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland. nea.malila@cancer.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16523006

Citation

Malila, Nea, et al. "Cancer Incidence in a Cohort of Finnish Male Smokers." European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), vol. 15, no. 2, 2006, pp. 103-7.
Malila N, Virtanen MJ, Virtamo J, et al. Cancer incidence in a cohort of Finnish male smokers. Eur J Cancer Prev. 2006;15(2):103-7.
Malila, N., Virtanen, M. J., Virtamo, J., Albanes, D., & Pukkala, E. (2006). Cancer incidence in a cohort of Finnish male smokers. European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), 15(2), 103-7.
Malila N, et al. Cancer Incidence in a Cohort of Finnish Male Smokers. Eur J Cancer Prev. 2006;15(2):103-7. PubMed PMID: 16523006.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cancer incidence in a cohort of Finnish male smokers. AU - Malila,Nea, AU - Virtanen,Mikko J, AU - Virtamo,Jarmo, AU - Albanes,Demetrius, AU - Pukkala,Eero, PY - 2006/3/9/pubmed PY - 2006/8/31/medline PY - 2006/3/9/entrez SP - 103 EP - 7 JF - European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) JO - Eur J Cancer Prev VL - 15 IS - 2 N2 - A total of 29,133 male smokers, aged 50-69 years, were recruited into the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study in 1984-1988. The nationwide Finnish Cancer Registry (FCR) recorded 5944 incident cases of cancer in this cohort through the end of 1999. Compared with the FCR data of the entire Finnish male population of same age the standardized incidence ratio (SIR) of total cancer in the ATBC cohort was 1.55 [95% confidence interval (CI) 1.51-1.59]. There was a significant excess of established smoking-related malignancies, such as lung cancer (SIR 2.45, 95% CI 2.35-2.56), and cancers of the tongue, mouth, pharynx, larynx, oesophagus, pancreas, stomach, liver, urinary bladder and kidney. In addition to these sites, cancers of the prostate and colon were slightly more common in the ATBC cohort than in the total Finnish male population (SIR 1.10, 95% CI 1.04-1.18 and SIR 1.14, 95% CI 1.00-1.30, respectively). In conclusion, the risk of many cancers was significantly higher in the ATBC Study cohort compared with the total Finnish male population of same age. In addition to the well known smoking-related cancers, cigarette smoking may increase slightly the risk of colon and prostate cancer, too. SN - 0959-8278 UR - https://www.unboundmedicine.com/medline/citation/16523006/Cancer_incidence_in_a_cohort_of_Finnish_male_smokers_ L2 - https://doi.org/10.1097/01.cej.0000197448.49239.60 DB - PRIME DP - Unbound Medicine ER -