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Compliance with treatment in osteoporosis patients--an ongoing problem.
Aust Fam Physician. 2006 Mar; 35(3):135-7.AF

Abstract

BACKGROUND

Osteoporosis is a chronic condition that generally requires long term therapy with agents such as bisphosphonates, selective oestrogen receptor modulators, or hormone therapy for fracture risk reduction to be apparent. However, compliance with therapy in the 'real world' setting has generally been less than that seen in clinical trials.

OBJECTIVE

This article reviews the trends of compliance and persistence with bisphosphonate therapy in patients with osteoporosis in the 'real world' setting.

DISCUSSION

Studies in Australia and overseas have shown that once weekly administration of bisphosphonates improves compliance with treatment compared with a daily regimen. However, although patients prefer once weekly bisphosphonates over daily treatment, compliance and persistence remained suboptimal in many patients receiving once weekly therapy. The introduction of less frequent dosing regimens such as once monthly or once yearly may increase compliance.

Authors+Show Affiliations

Institute of Bone and Joint Research, University of Sydney, New South Wales. sambrook@med.usyd.edu.au

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16525527

Citation

Sambrook, Philip. "Compliance With Treatment in Osteoporosis Patients--an Ongoing Problem." Australian Family Physician, vol. 35, no. 3, 2006, pp. 135-7.
Sambrook P. Compliance with treatment in osteoporosis patients--an ongoing problem. Aust Fam Physician. 2006;35(3):135-7.
Sambrook, P. (2006). Compliance with treatment in osteoporosis patients--an ongoing problem. Australian Family Physician, 35(3), 135-7.
Sambrook P. Compliance With Treatment in Osteoporosis Patients--an Ongoing Problem. Aust Fam Physician. 2006;35(3):135-7. PubMed PMID: 16525527.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Compliance with treatment in osteoporosis patients--an ongoing problem. A1 - Sambrook,Philip, PY - 2006/3/10/pubmed PY - 2006/5/13/medline PY - 2006/3/10/entrez SP - 135 EP - 7 JF - Australian family physician JO - Aust Fam Physician VL - 35 IS - 3 N2 - BACKGROUND: Osteoporosis is a chronic condition that generally requires long term therapy with agents such as bisphosphonates, selective oestrogen receptor modulators, or hormone therapy for fracture risk reduction to be apparent. However, compliance with therapy in the 'real world' setting has generally been less than that seen in clinical trials. OBJECTIVE: This article reviews the trends of compliance and persistence with bisphosphonate therapy in patients with osteoporosis in the 'real world' setting. DISCUSSION: Studies in Australia and overseas have shown that once weekly administration of bisphosphonates improves compliance with treatment compared with a daily regimen. However, although patients prefer once weekly bisphosphonates over daily treatment, compliance and persistence remained suboptimal in many patients receiving once weekly therapy. The introduction of less frequent dosing regimens such as once monthly or once yearly may increase compliance. SN - 0300-8495 UR - https://www.unboundmedicine.com/medline/citation/16525527/Compliance_with_treatment_in_osteoporosis_patients__an_ongoing_problem_ L2 - http://www.racgp.org.au/afp/200603/3611 DB - PRIME DP - Unbound Medicine ER -