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Diagnosis and management of diastolic dysfunction and heart failure.

Abstract

Diastolic heart failure occurs when signs and symptoms of heart failure are present but left ventricular systolic function is preserved (i.e., ejection fraction greater than 45 percent). The incidence of diastolic heart failure increases with age; therefore, 50 percent of older patients with heart failure may have isolated diastolic dysfunction. With early diagnosis and proper management the prognosis of diastolic dysfunction is more favorable than that of systolic dysfunction. Distinguishing diastolic from systolic heart failure is essential because the optimal therapy for one may aggravate the other. Although diastolic heart failure is clinically and radiographically indistinguishable from systolic heart failure, normal ejection fraction and abnormal diastolic function in the presence of symptoms and signs of heart failure confirm diastolic heart failure. The pharmacologic therapies of choice for diastolic heart failure are angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, diuretics, and beta blockers.

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  • Authors+Show Affiliations

    ,

    Department of Cardiology, Utkal University, Sriram Chandra Bhanja Medical College, Cuttack, Orissa, India.

    , , ,

    Source

    American family physician 73:5 2006 Mar 01 pg 841-6

    MeSH

    Cardiovascular Agents
    Clinical Trials as Topic
    Diagnosis, Differential
    Diastole
    Heart Failure
    Humans
    Ventricular Dysfunction, Left
    Ventricular Function, Left

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    16529092

    Citation

    Satpathy, Chhabi, et al. "Diagnosis and Management of Diastolic Dysfunction and Heart Failure." American Family Physician, vol. 73, no. 5, 2006, pp. 841-6.
    Satpathy C, Mishra TK, Satpathy R, et al. Diagnosis and management of diastolic dysfunction and heart failure. Am Fam Physician. 2006;73(5):841-6.
    Satpathy, C., Mishra, T. K., Satpathy, R., Satpathy, H. K., & Barone, E. (2006). Diagnosis and management of diastolic dysfunction and heart failure. American Family Physician, 73(5), pp. 841-6.
    Satpathy C, et al. Diagnosis and Management of Diastolic Dysfunction and Heart Failure. Am Fam Physician. 2006 Mar 1;73(5):841-6. PubMed PMID: 16529092.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Diagnosis and management of diastolic dysfunction and heart failure. AU - Satpathy,Chhabi, AU - Mishra,Trinath K, AU - Satpathy,Ruby, AU - Satpathy,Hemant K, AU - Barone,Eugene, PY - 2006/3/15/pubmed PY - 2006/3/29/medline PY - 2006/3/15/entrez SP - 841 EP - 6 JF - American family physician JO - Am Fam Physician VL - 73 IS - 5 N2 - Diastolic heart failure occurs when signs and symptoms of heart failure are present but left ventricular systolic function is preserved (i.e., ejection fraction greater than 45 percent). The incidence of diastolic heart failure increases with age; therefore, 50 percent of older patients with heart failure may have isolated diastolic dysfunction. With early diagnosis and proper management the prognosis of diastolic dysfunction is more favorable than that of systolic dysfunction. Distinguishing diastolic from systolic heart failure is essential because the optimal therapy for one may aggravate the other. Although diastolic heart failure is clinically and radiographically indistinguishable from systolic heart failure, normal ejection fraction and abnormal diastolic function in the presence of symptoms and signs of heart failure confirm diastolic heart failure. The pharmacologic therapies of choice for diastolic heart failure are angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, diuretics, and beta blockers. SN - 0002-838X UR - https://www.unboundmedicine.com/medline/citation/16529092/Diagnosis_and_management_of_diastolic_dysfunction_and_heart_failure_ L2 - http://www.aafp.org/link_out?pmid=16529092 DB - PRIME DP - Unbound Medicine ER -