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Using registry data to evaluate the 2004 pneumococcal conjugate vaccine shortage.
Am J Prev Med. 2006 Apr; 30(4):347-50.AJ

Abstract

BACKGROUND

The most recent pneumococcal conjugate vaccine (PCV7) shortage occurred between December 2003 and September 2004. To ensure vaccination of the highest-risk children, the Centers for Disease Control and Prevention recommended that providers delay administration of the third and fourth doses of vaccine to healthy children. We used Michigan Child Immunization Registry (MCIR) data collected from September 1, 2001 to November 30, 2004 to evaluate changes in PCV7 coverage.

METHODS

Vaccination and demographic data from MCIR were reviewed for 420,733 children born between September 2001 and August 2004. Main outcome measures were the proportion of children who received the third dose of PCV7 by 7 months of age and the fourth dose of PCV7 by 16 months of age. Vaccine coverage for measles, mumps, and rubella vaccine (MMR) and diphtheria, tetanus, and acellular pertussis vaccine (DTaP) was used for comparison, as these vaccines were abundant during this time period and their administration schedule is the same as the third and fourth doses of PCV7, respectively. Data analysis was conducted in spring 2005.

RESULTS

Coverage for the third dose of DTaP and the first dose of MMR remained steady, while PCV7 coverage for the third dose dropped from 29% to 11%, and the fourth dose dropped from 27% to 22% in the month following the recommendations to defer doses. Coverage returned close to pre-shortage levels shortly after the recommendations to resume the normal schedule. PCV7 coverage trends were similar for children seen in the private or public sector.

CONCLUSIONS

Registry data can be useful for evaluating vaccination coverage trends during a shortage. Our findings suggest that providers were compliant with recommendations to alter vaccine administration during the shortage.

Authors+Show Affiliations

National Immunization Program, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. nallred@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16530623

Citation

Allred, Norma J., et al. "Using Registry Data to Evaluate the 2004 Pneumococcal Conjugate Vaccine Shortage." American Journal of Preventive Medicine, vol. 30, no. 4, 2006, pp. 347-50.
Allred NJ, Stevenson JM, Kolasa M, et al. Using registry data to evaluate the 2004 pneumococcal conjugate vaccine shortage. Am J Prev Med. 2006;30(4):347-50.
Allred, N. J., Stevenson, J. M., Kolasa, M., Bartlett, D. L., Schieber, R., Enger, K. S., & Shefer, A. (2006). Using registry data to evaluate the 2004 pneumococcal conjugate vaccine shortage. American Journal of Preventive Medicine, 30(4), 347-50.
Allred NJ, et al. Using Registry Data to Evaluate the 2004 Pneumococcal Conjugate Vaccine Shortage. Am J Prev Med. 2006;30(4):347-50. PubMed PMID: 16530623.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Using registry data to evaluate the 2004 pneumococcal conjugate vaccine shortage. AU - Allred,Norma J, AU - Stevenson,John M, AU - Kolasa,Maureen, AU - Bartlett,Diana L, AU - Schieber,Richard, AU - Enger,Kyle S, AU - Shefer,Abigail, PY - 2005/08/01/received PY - 2005/10/21/revised PY - 2005/11/29/accepted PY - 2006/3/15/pubmed PY - 2006/11/10/medline PY - 2006/3/15/entrez SP - 347 EP - 50 JF - American journal of preventive medicine JO - Am J Prev Med VL - 30 IS - 4 N2 - BACKGROUND: The most recent pneumococcal conjugate vaccine (PCV7) shortage occurred between December 2003 and September 2004. To ensure vaccination of the highest-risk children, the Centers for Disease Control and Prevention recommended that providers delay administration of the third and fourth doses of vaccine to healthy children. We used Michigan Child Immunization Registry (MCIR) data collected from September 1, 2001 to November 30, 2004 to evaluate changes in PCV7 coverage. METHODS: Vaccination and demographic data from MCIR were reviewed for 420,733 children born between September 2001 and August 2004. Main outcome measures were the proportion of children who received the third dose of PCV7 by 7 months of age and the fourth dose of PCV7 by 16 months of age. Vaccine coverage for measles, mumps, and rubella vaccine (MMR) and diphtheria, tetanus, and acellular pertussis vaccine (DTaP) was used for comparison, as these vaccines were abundant during this time period and their administration schedule is the same as the third and fourth doses of PCV7, respectively. Data analysis was conducted in spring 2005. RESULTS: Coverage for the third dose of DTaP and the first dose of MMR remained steady, while PCV7 coverage for the third dose dropped from 29% to 11%, and the fourth dose dropped from 27% to 22% in the month following the recommendations to defer doses. Coverage returned close to pre-shortage levels shortly after the recommendations to resume the normal schedule. PCV7 coverage trends were similar for children seen in the private or public sector. CONCLUSIONS: Registry data can be useful for evaluating vaccination coverage trends during a shortage. Our findings suggest that providers were compliant with recommendations to alter vaccine administration during the shortage. SN - 0749-3797 UR - https://www.unboundmedicine.com/medline/citation/16530623/Using_registry_data_to_evaluate_the_2004_pneumococcal_conjugate_vaccine_shortage_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0749-3797(05)00520-9 DB - PRIME DP - Unbound Medicine ER -