Tags

Type your tag names separated by a space and hit enter

Cervicitis and genitourinary symptoms in women culture positive for Mycoplasma genitalium.
Am J Reprod Immunol 2006; 55(4):265-75AJ

Abstract

PROBLEM

Mycoplasma genitalium has been associated with male urethritis. We sought to relate M. genitalium to genitourinary signs and symptoms in women.

METHOD OF STUDY

We compared 26 culture-positive women (group 1), 257 additional polymerase chain reaction-positive women (group 2), and 107 negative control women. We used logistic regression to evaluate signs and symptoms, controlling for co-infections, pregnancy, age, and intervention group assignment.

RESULTS

Comparing group 1 with controls, we found significantly elevated odds ratios (ORs) for intermediate vaginal discharge (OR = 5.4; 95% confidence interval 1.01, 29.2) and action in response to discharge [3.9 (1.1, 13.5)]. Non-significant increases were observed for pathologic vaginal discharge [3.8 (0.78, 18.2)], pathologic dyspareunia [1.5 (0.25, 9.0)], vaginal odor [2.1 (0.75, 5.7)], and cervical mucopus [4.1 (0.74, 22.4)]. Group 2 results were similar, but showed no increase in cervical mucopus relative to controls.

CONCLUSION

Infection with M. genitalium in women is independently related to increased genitourinary symptomatology.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, School of Medicine, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA. kortej@uthscsa.edu

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

16533338

Citation

Korte, Jeffrey E., et al. "Cervicitis and Genitourinary Symptoms in Women Culture Positive for Mycoplasma Genitalium." American Journal of Reproductive Immunology (New York, N.Y. : 1989), vol. 55, no. 4, 2006, pp. 265-75.
Korte JE, Baseman JB, Cagle MP, et al. Cervicitis and genitourinary symptoms in women culture positive for Mycoplasma genitalium. Am J Reprod Immunol. 2006;55(4):265-75.
Korte, J. E., Baseman, J. B., Cagle, M. P., Herrera, C., Piper, J. M., Holden, A. E., ... Shain, R. N. (2006). Cervicitis and genitourinary symptoms in women culture positive for Mycoplasma genitalium. American Journal of Reproductive Immunology (New York, N.Y. : 1989), 55(4), pp. 265-75.
Korte JE, et al. Cervicitis and Genitourinary Symptoms in Women Culture Positive for Mycoplasma Genitalium. Am J Reprod Immunol. 2006;55(4):265-75. PubMed PMID: 16533338.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cervicitis and genitourinary symptoms in women culture positive for Mycoplasma genitalium. AU - Korte,Jeffrey E, AU - Baseman,Joel B, AU - Cagle,Marianna P, AU - Herrera,Caleb, AU - Piper,Jeanna M, AU - Holden,Alan E C, AU - Perdue,Sondra T, AU - Champion,Jane D, AU - Shain,Rochelle N, PY - 2006/3/15/pubmed PY - 2006/5/25/medline PY - 2006/3/15/entrez SP - 265 EP - 75 JF - American journal of reproductive immunology (New York, N.Y. : 1989) JO - Am. J. Reprod. Immunol. VL - 55 IS - 4 N2 - PROBLEM: Mycoplasma genitalium has been associated with male urethritis. We sought to relate M. genitalium to genitourinary signs and symptoms in women. METHOD OF STUDY: We compared 26 culture-positive women (group 1), 257 additional polymerase chain reaction-positive women (group 2), and 107 negative control women. We used logistic regression to evaluate signs and symptoms, controlling for co-infections, pregnancy, age, and intervention group assignment. RESULTS: Comparing group 1 with controls, we found significantly elevated odds ratios (ORs) for intermediate vaginal discharge (OR = 5.4; 95% confidence interval 1.01, 29.2) and action in response to discharge [3.9 (1.1, 13.5)]. Non-significant increases were observed for pathologic vaginal discharge [3.8 (0.78, 18.2)], pathologic dyspareunia [1.5 (0.25, 9.0)], vaginal odor [2.1 (0.75, 5.7)], and cervical mucopus [4.1 (0.74, 22.4)]. Group 2 results were similar, but showed no increase in cervical mucopus relative to controls. CONCLUSION: Infection with M. genitalium in women is independently related to increased genitourinary symptomatology. SN - 1046-7408 UR - https://www.unboundmedicine.com/medline/citation/16533338/Cervicitis_and_genitourinary_symptoms_in_women_culture_positive_for_Mycoplasma_genitalium_ L2 - https://doi.org/10.1111/j.1600-0897.2005.00359.x DB - PRIME DP - Unbound Medicine ER -