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[Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation].
Nan Fang Yi Ke Da Xue Xue Bao. 2006 Mar; 26(3):287-9.NF

Abstract

OBJECTIVE

To compare the unconsciousness prediction probability (Pk) estimated by approximate entropy (ApEn) and bispectral index (BIS) during the sedation produced by target-controlled infusion (TCI) of propofol.

METHODS

Twenty patients (ASA class I-II) scheduled for elective lower limb operations under epidural anesthesia were studied. TCI of propofol was initiated at target plasma concentration of 0.5 microg/ml, and increased by 0.3 to 0.5 microg/ml until loss of consciousness, and then decreased until consciousness recovery. Each target plasma concentration of propofol lasted for 12 min. ApEn and BIS were recorded simultaneously during the periods of consciousness and unconsciousness every 3 min. The Pk of unconsciousness with ApEn and BIS were calculated and compared.

RESULTS

ApEn was 0.84+/-0.05 in the state of consciousness and 0.71+/-0.06 upon loss of consciousness, and BIS in the corresponding stages were 80.2+/-6.2 and 67.3+/-7.9, respectively. The Pk of unconsciousness between ApEn (Pk=0.97+/-0.06) and BIS (Pk=0.91+/-0.11) did not significantly differ (P>0.05).

CONCLUSION

ApEn as well as BIS is acceptable for predicting consciousness and unconsciousness produced by TCI propofol.

Authors+Show Affiliations

Department of Anesthesiology, General Hospital of PLA, Beijing 100853, China. ouyangmm2008@yahoo.com.cnNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

16546728

Citation

Ouyang, Ming-wen, and Hong Zhang. "[Comparison of Unconsciousness Prediction Probability With Approximate Entropy and Bispectral Index During Sedation]." Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, vol. 26, no. 3, 2006, pp. 287-9.
Ouyang MW, Zhang H. [Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation]. Nan Fang Yi Ke Da Xue Xue Bao. 2006;26(3):287-9.
Ouyang, M. W., & Zhang, H. (2006). [Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation]. Nan Fang Yi Ke Da Xue Xue Bao = Journal of Southern Medical University, 26(3), 287-9.
Ouyang MW, Zhang H. [Comparison of Unconsciousness Prediction Probability With Approximate Entropy and Bispectral Index During Sedation]. Nan Fang Yi Ke Da Xue Xue Bao. 2006;26(3):287-9. PubMed PMID: 16546728.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Comparison of unconsciousness prediction probability with approximate entropy and bispectral index during sedation]. AU - Ouyang,Ming-wen, AU - Zhang,Hong, PY - 2006/3/21/pubmed PY - 2008/4/15/medline PY - 2006/3/21/entrez SP - 287 EP - 9 JF - Nan fang yi ke da xue xue bao = Journal of Southern Medical University JO - Nan Fang Yi Ke Da Xue Xue Bao VL - 26 IS - 3 N2 - OBJECTIVE: To compare the unconsciousness prediction probability (Pk) estimated by approximate entropy (ApEn) and bispectral index (BIS) during the sedation produced by target-controlled infusion (TCI) of propofol. METHODS: Twenty patients (ASA class I-II) scheduled for elective lower limb operations under epidural anesthesia were studied. TCI of propofol was initiated at target plasma concentration of 0.5 microg/ml, and increased by 0.3 to 0.5 microg/ml until loss of consciousness, and then decreased until consciousness recovery. Each target plasma concentration of propofol lasted for 12 min. ApEn and BIS were recorded simultaneously during the periods of consciousness and unconsciousness every 3 min. The Pk of unconsciousness with ApEn and BIS were calculated and compared. RESULTS: ApEn was 0.84+/-0.05 in the state of consciousness and 0.71+/-0.06 upon loss of consciousness, and BIS in the corresponding stages were 80.2+/-6.2 and 67.3+/-7.9, respectively. The Pk of unconsciousness between ApEn (Pk=0.97+/-0.06) and BIS (Pk=0.91+/-0.11) did not significantly differ (P>0.05). CONCLUSION: ApEn as well as BIS is acceptable for predicting consciousness and unconsciousness produced by TCI propofol. SN - 1673-4254 UR - https://www.unboundmedicine.com/medline/citation/16546728/[Comparison_of_unconsciousness_prediction_probability_with_approximate_entropy_and_bispectral_index_during_sedation]_ L2 - https://antibodies.cancer.gov/detail/CPTC-APEX1-2 DB - PRIME DP - Unbound Medicine ER -