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Barriers to optimizing vitamin D3 intake for the elderly.
J Nutr 2006; 136(4):1123-5JN

Abstract

Available data on metabolic utilization of vitamin D3 indicate a total daily requirement of approximately 4000 international units (iu) (100 microg) or twice the current tolerable upper intake level (UL). In young individuals, most of this comes from the skin. However, cutaneous vitamin D3 synthesis declines with age, creating a need for increasing oral intake to maintain optimal serum 25-hydroxyvitamin D [25(OH)D] concentrations. Estimates of the population distribution of serum 25(OH)D values, coupled with available dose-response data, indicate that it would require input of an additional 2600 iu/d (65 microg/d) of oral vitamin D3 to ensure that 97.5% of older women have 25(OH)D values at or above desirable levels. The age-related decline in cutaneous input, taken together with the UL, creates a substantial barrier to the deployment of public health strategies to optimize vitamin D status in the elderly.

Authors+Show Affiliations

Creighton University, Omaha, NE 68178, USA. rheaney@creighton.edu

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16549492

Citation

Heaney, Robert P.. "Barriers to Optimizing Vitamin D3 Intake for the Elderly." The Journal of Nutrition, vol. 136, no. 4, 2006, pp. 1123-5.
Heaney RP. Barriers to optimizing vitamin D3 intake for the elderly. J Nutr. 2006;136(4):1123-5.
Heaney, R. P. (2006). Barriers to optimizing vitamin D3 intake for the elderly. The Journal of Nutrition, 136(4), pp. 1123-5.
Heaney RP. Barriers to Optimizing Vitamin D3 Intake for the Elderly. J Nutr. 2006;136(4):1123-5. PubMed PMID: 16549492.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Barriers to optimizing vitamin D3 intake for the elderly. A1 - Heaney,Robert P, PY - 2006/3/22/pubmed PY - 2006/5/4/medline PY - 2006/3/22/entrez SP - 1123 EP - 5 JF - The Journal of nutrition JO - J. Nutr. VL - 136 IS - 4 N2 - Available data on metabolic utilization of vitamin D3 indicate a total daily requirement of approximately 4000 international units (iu) (100 microg) or twice the current tolerable upper intake level (UL). In young individuals, most of this comes from the skin. However, cutaneous vitamin D3 synthesis declines with age, creating a need for increasing oral intake to maintain optimal serum 25-hydroxyvitamin D [25(OH)D] concentrations. Estimates of the population distribution of serum 25(OH)D values, coupled with available dose-response data, indicate that it would require input of an additional 2600 iu/d (65 microg/d) of oral vitamin D3 to ensure that 97.5% of older women have 25(OH)D values at or above desirable levels. The age-related decline in cutaneous input, taken together with the UL, creates a substantial barrier to the deployment of public health strategies to optimize vitamin D status in the elderly. SN - 0022-3166 UR - https://www.unboundmedicine.com/medline/citation/16549492/full_citation L2 - https://academic.oup.com/jn/article-lookup/doi/10.1093/jn/136.4.1123 DB - PRIME DP - Unbound Medicine ER -