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Fatal motor vehicle crashes among veterans of the 1991 Gulf War and exposure to munitions demolitions at Khamisiyah: a nested case-control study.
Am J Ind Med. 2006 Apr; 49(4):261-70.AJ

Abstract

BACKGROUND

A proposed explanation for the observed higher risk of fatal motor vehicle crashes (MVC) among 1991 Gulf War-deployed veterans is neurocognitive deficits resulting from nerve agent exposure at Khamisiyah, Iraq. Our objective was to assess any association between postwar fatal MVC and possible nerve agent exposure based on 2000 modeled plume data.

METHODS

Cases were defined as MVC deaths with a record in the Department of Transportation Fatality Analysis Reporting System through 1995. Cases (n = 282) and controls (n = 3,131) were derived from a larger nested case-control study of Gulf War-era veterans and limited to Army, male, deployed personnel. Exposure and cumulative dose by case-control status were analyzed using multivariate techniques.

RESULTS

Exposure status was not associated with fatal MVC (OR 0.96, 95% CI 0.72-1.26), nor were tertiles of cumulative dose.

CONCLUSIONS

Findings do not support an association between possible exposures at Khamisiyah and postwar fatal MVC among Gulf War veterans.

Authors+Show Affiliations

Center for Force Health Protection Studies, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814-4799, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

16550564

Citation

Gackstetter, Gary D., et al. "Fatal Motor Vehicle Crashes Among Veterans of the 1991 Gulf War and Exposure to Munitions Demolitions at Khamisiyah: a Nested Case-control Study." American Journal of Industrial Medicine, vol. 49, no. 4, 2006, pp. 261-70.
Gackstetter GD, Hooper TI, DeBakey SF, et al. Fatal motor vehicle crashes among veterans of the 1991 Gulf War and exposure to munitions demolitions at Khamisiyah: a nested case-control study. Am J Ind Med. 2006;49(4):261-70.
Gackstetter, G. D., Hooper, T. I., DeBakey, S. F., Johnson, A., Nagaraj, B. E., Heller, J. M., & Kang, H. K. (2006). Fatal motor vehicle crashes among veterans of the 1991 Gulf War and exposure to munitions demolitions at Khamisiyah: a nested case-control study. American Journal of Industrial Medicine, 49(4), 261-70.
Gackstetter GD, et al. Fatal Motor Vehicle Crashes Among Veterans of the 1991 Gulf War and Exposure to Munitions Demolitions at Khamisiyah: a Nested Case-control Study. Am J Ind Med. 2006;49(4):261-70. PubMed PMID: 16550564.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fatal motor vehicle crashes among veterans of the 1991 Gulf War and exposure to munitions demolitions at Khamisiyah: a nested case-control study. AU - Gackstetter,Gary D, AU - Hooper,Tomoko I, AU - DeBakey,Samar F, AU - Johnson,Amy, AU - Nagaraj,Barbara E, AU - Heller,Jack M, AU - Kang,Han K, PY - 2006/3/22/pubmed PY - 2006/9/13/medline PY - 2006/3/22/entrez SP - 261 EP - 70 JF - American journal of industrial medicine JO - Am J Ind Med VL - 49 IS - 4 N2 - BACKGROUND: A proposed explanation for the observed higher risk of fatal motor vehicle crashes (MVC) among 1991 Gulf War-deployed veterans is neurocognitive deficits resulting from nerve agent exposure at Khamisiyah, Iraq. Our objective was to assess any association between postwar fatal MVC and possible nerve agent exposure based on 2000 modeled plume data. METHODS: Cases were defined as MVC deaths with a record in the Department of Transportation Fatality Analysis Reporting System through 1995. Cases (n = 282) and controls (n = 3,131) were derived from a larger nested case-control study of Gulf War-era veterans and limited to Army, male, deployed personnel. Exposure and cumulative dose by case-control status were analyzed using multivariate techniques. RESULTS: Exposure status was not associated with fatal MVC (OR 0.96, 95% CI 0.72-1.26), nor were tertiles of cumulative dose. CONCLUSIONS: Findings do not support an association between possible exposures at Khamisiyah and postwar fatal MVC among Gulf War veterans. SN - 0271-3586 UR - https://www.unboundmedicine.com/medline/citation/16550564/Fatal_motor_vehicle_crashes_among_veterans_of_the_1991_Gulf_War_and_exposure_to_munitions_demolitions_at_Khamisiyah:_a_nested_case_control_study_ L2 - https://doi.org/10.1002/ajim.20280 DB - PRIME DP - Unbound Medicine ER -