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Alkaloids from the roots of Aconitum pseudo-laeve var. erectum.
J Nat Prod. 2006 Mar; 69(3):400-2.JN

Abstract

One new quinazoline (1) and two new norditerpenoid (2 and 3) alkaloids along with 10 known compounds were isolated from the roots of Aconitum pseudo-laeve var. erectum. The new alkaloids were assigned as 2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoic acid methyl ester (1), 18-O-2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoyllycoctonine (2), and 14-O-acetyl-8-O-methyl-18-O-2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoylcammaconine (3). The structures of the new alkaloids were established by spectroscopic methods. This is the first report of the 2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoyl ester group being found as an acyl substituent in norditerpenoid alkaloids (compounds 2 and 3).

Authors+Show Affiliations

Natural Products Research Institute and College of Pharmacy, Seoul National University, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16562844

Citation

Shim, Sang Hee, et al. "Alkaloids From the Roots of Aconitum Pseudo-laeve Var. Erectum." Journal of Natural Products, vol. 69, no. 3, 2006, pp. 400-2.
Shim SH, Kim JS, Son KH, et al. Alkaloids from the roots of Aconitum pseudo-laeve var. erectum. J Nat Prod. 2006;69(3):400-2.
Shim, S. H., Kim, J. S., Son, K. H., Bae, K. H., & Kang, S. S. (2006). Alkaloids from the roots of Aconitum pseudo-laeve var. erectum. Journal of Natural Products, 69(3), 400-2.
Shim SH, et al. Alkaloids From the Roots of Aconitum Pseudo-laeve Var. Erectum. J Nat Prod. 2006;69(3):400-2. PubMed PMID: 16562844.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alkaloids from the roots of Aconitum pseudo-laeve var. erectum. AU - Shim,Sang Hee, AU - Kim,Ju Sun, AU - Son,Kun Ho, AU - Bae,Ki Hwan, AU - Kang,Sam Sik, PY - 2006/3/28/pubmed PY - 2006/5/9/medline PY - 2006/3/28/entrez SP - 400 EP - 2 JF - Journal of natural products JO - J Nat Prod VL - 69 IS - 3 N2 - One new quinazoline (1) and two new norditerpenoid (2 and 3) alkaloids along with 10 known compounds were isolated from the roots of Aconitum pseudo-laeve var. erectum. The new alkaloids were assigned as 2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoic acid methyl ester (1), 18-O-2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoyllycoctonine (2), and 14-O-acetyl-8-O-methyl-18-O-2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoylcammaconine (3). The structures of the new alkaloids were established by spectroscopic methods. This is the first report of the 2-(2-methyl-4-oxo-4H-quinazoline-3-yl)benzoyl ester group being found as an acyl substituent in norditerpenoid alkaloids (compounds 2 and 3). SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/16562844/Alkaloids_from_the_roots_of_Aconitum_pseudo_laeve_var__erectum_ L2 - https://doi.org/10.1021/np058073p DB - PRIME DP - Unbound Medicine ER -