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Identifying Hfq-binding small RNA targets in Escherichia coli.
Biochem Biophys Res Commun. 2006 May 12; 343(3):950-5.BB

Abstract

The Hfq-binding small RNAs (sRNAs) have recently drawn much attention as regulators of translation in Escherichia coli. We attempt to identify the targets of this class of sRNAs in genome scale and gain further insight into the complexity of translational regulation induced by Hfq-binding sRNAs. Using a new alignment algorithm, most known negatively regulated targets of Hfq-binding sRNAs were identified. The results also show several interesting aspects of the regulatory function of Hfq-binding sRNAs.

Authors+Show Affiliations

Bioinformatics Laboratory and National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16574072

Citation

Zhang, Yong, et al. "Identifying Hfq-binding Small RNA Targets in Escherichia Coli." Biochemical and Biophysical Research Communications, vol. 343, no. 3, 2006, pp. 950-5.
Zhang Y, Sun S, Wu T, et al. Identifying Hfq-binding small RNA targets in Escherichia coli. Biochem Biophys Res Commun. 2006;343(3):950-5.
Zhang, Y., Sun, S., Wu, T., Wang, J., Liu, C., Chen, L., Zhu, X., Zhao, Y., Zhang, Z., Shi, B., Lu, H., & Chen, R. (2006). Identifying Hfq-binding small RNA targets in Escherichia coli. Biochemical and Biophysical Research Communications, 343(3), 950-5.
Zhang Y, et al. Identifying Hfq-binding Small RNA Targets in Escherichia Coli. Biochem Biophys Res Commun. 2006 May 12;343(3):950-5. PubMed PMID: 16574072.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Identifying Hfq-binding small RNA targets in Escherichia coli. AU - Zhang,Yong, AU - Sun,Shiwei, AU - Wu,Tao, AU - Wang,Jie, AU - Liu,Changning, AU - Chen,Lan, AU - Zhu,Xiaopeng, AU - Zhao,Yi, AU - Zhang,Zhihua, AU - Shi,Baochen, AU - Lu,Hongchao, AU - Chen,Runsheng, Y1 - 2006/03/20/ PY - 2006/02/09/received PY - 2006/02/22/accepted PY - 2006/4/1/pubmed PY - 2006/5/25/medline PY - 2006/4/1/entrez SP - 950 EP - 5 JF - Biochemical and biophysical research communications JO - Biochem Biophys Res Commun VL - 343 IS - 3 N2 - The Hfq-binding small RNAs (sRNAs) have recently drawn much attention as regulators of translation in Escherichia coli. We attempt to identify the targets of this class of sRNAs in genome scale and gain further insight into the complexity of translational regulation induced by Hfq-binding sRNAs. Using a new alignment algorithm, most known negatively regulated targets of Hfq-binding sRNAs were identified. The results also show several interesting aspects of the regulatory function of Hfq-binding sRNAs. SN - 0006-291X UR - https://www.unboundmedicine.com/medline/citation/16574072/Identifying_Hfq_binding_small_RNA_targets_in_Escherichia_coli_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0006-291X(06)00430-X DB - PRIME DP - Unbound Medicine ER -