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[The effect of inactivation of the exo- and endopolyphosphatase genes PPX1 and PPN1 on the level of different polyphosphates in the yeast Saccharomyces cerevisiae].
Mikrobiologiia. 2006 Jan-Feb; 75(1):35-9.M

Abstract

The inactivation of the PPX1 and PPN1 genes, which encode the major enzymes of polyphosphate degradation (exopolyphosphatase and endopolyphosphatase, respectively), was found to exert different effects on the content of different polyphosphates in the yeast Saccharomyces cerevisiae. The content of relatively low-molecular-weight acid-soluble polyphosphates in mutant yeast strains is inversely proportional to the exopolyphosphatase activity of the cytosol. At the same time, the mutation of these genes exerts no effect on salt-soluble polyphosphates. The content of high-molecular-weight alkali-soluble polyphosphates increases twofold in a mutant with inactivated genes of both exopolyphosphatase and endopolyphosphatase. The data obtained confirm the earlier suggestion that the metabolic pathways of particular polyphosphates in yeasts are different.

Authors

Kulakovskaia TV
No affiliation info available
Trilisenko LV
No affiliation info available
Lichko LP
No affiliation info available
Vagabov VM
No affiliation info available
Kulaev IS
No affiliation info available

MeSH

Acid Anhydride HydrolasesCytoplasmMutationPolyphosphatesSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteins

Pub Type(s)

Journal Article

Language

rus

PubMed ID

16579441

Citation

Kulakovskaia, T V., et al. "[The Effect of Inactivation of the Exo- and Endopolyphosphatase Genes PPX1 and PPN1 On the Level of Different Polyphosphates in the Yeast Saccharomyces Cerevisiae]." Mikrobiologiia, vol. 75, no. 1, 2006, pp. 35-9.
Kulakovskaia TV, Trilisenko LV, Lichko LP, et al. [The effect of inactivation of the exo- and endopolyphosphatase genes PPX1 and PPN1 on the level of different polyphosphates in the yeast Saccharomyces cerevisiae]. Mikrobiologiia. 2006;75(1):35-9.
Kulakovskaia, T. V., Trilisenko, L. V., Lichko, L. P., Vagabov, V. M., & Kulaev, I. S. (2006). [The effect of inactivation of the exo- and endopolyphosphatase genes PPX1 and PPN1 on the level of different polyphosphates in the yeast Saccharomyces cerevisiae]. Mikrobiologiia, 75(1), 35-9.
Kulakovskaia TV, et al. [The Effect of Inactivation of the Exo- and Endopolyphosphatase Genes PPX1 and PPN1 On the Level of Different Polyphosphates in the Yeast Saccharomyces Cerevisiae]. Mikrobiologiia. 2006 Jan-Feb;75(1):35-9. PubMed PMID: 16579441.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The effect of inactivation of the exo- and endopolyphosphatase genes PPX1 and PPN1 on the level of different polyphosphates in the yeast Saccharomyces cerevisiae]. AU - Kulakovskaia,T V, AU - Trilisenko,L V, AU - Lichko,L P, AU - Vagabov,V M, AU - Kulaev,I S, PY - 2006/4/4/pubmed PY - 2006/5/19/medline PY - 2006/4/4/entrez SP - 35 EP - 9 JF - Mikrobiologiia JO - Mikrobiologiia VL - 75 IS - 1 N2 - The inactivation of the PPX1 and PPN1 genes, which encode the major enzymes of polyphosphate degradation (exopolyphosphatase and endopolyphosphatase, respectively), was found to exert different effects on the content of different polyphosphates in the yeast Saccharomyces cerevisiae. The content of relatively low-molecular-weight acid-soluble polyphosphates in mutant yeast strains is inversely proportional to the exopolyphosphatase activity of the cytosol. At the same time, the mutation of these genes exerts no effect on salt-soluble polyphosphates. The content of high-molecular-weight alkali-soluble polyphosphates increases twofold in a mutant with inactivated genes of both exopolyphosphatase and endopolyphosphatase. The data obtained confirm the earlier suggestion that the metabolic pathways of particular polyphosphates in yeasts are different. SN - 0026-3656 UR - https://www.unboundmedicine.com/medline/citation/16579441/[The_effect_of_inactivation_of_the_exo__and_endopolyphosphatase_genes_PPX1_and_PPN1_on_the_level_of_different_polyphosphates_in_the_yeast_Saccharomyces_cerevisiae]_ DB - PRIME DP - Unbound Medicine ER -