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Comparison of autologous rectus fascia and cadaveric fascia in pubovaginal sling continence outcomes.
Am J Obstet Gynecol. 2006 May; 194(5):1444-9.AJ

Abstract

OBJECTIVE

The purpose of this study was to compare autologous versus cadaveric grafts in pubovaginal slings.

STUDY DESIGN

Women who had pubovaginal slings from 1994 to 2003 completed history, questionnaires, prolapse staging, and cough stress testing. Failure was defined by recurrent urinary incontinence symptoms and reoperation for stress incontinence. Group differences were evaluated using Student t test or chi-square test. The log-rank test was used to evaluate time to failure between the groups.

RESULTS

Of 303 women enrolled, 153 had autologous and 150 had cadaveric grafts. Regular urine leakage (39.6% vs 28.3%, P = .04) and reoperation for stress incontinence (12.7% vs 3.3%, P = .003) occurred more in the cadaveric versus autologous group, respectively. Adjusting for differing follow-up times, the cadaveric versus autologous group experienced higher rates of urinary incontinence (16 vs 5 per 100 women-years, P < .0001) and higher rates of reoperation (4 vs 1 per 100 women-years, P < .0003).

CONCLUSION

Autologous grafts used in pubovaginal slings have superior continence outcomes compared with cadaveric fascia.

Authors+Show Affiliations

Division of Urogynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, The University of Pittsburgh Health Sciences Center, Magee-Womens Hospital, Pittsburgh, PA, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16579930

Citation

Howden, Nancy S., et al. "Comparison of Autologous Rectus Fascia and Cadaveric Fascia in Pubovaginal Sling Continence Outcomes." American Journal of Obstetrics and Gynecology, vol. 194, no. 5, 2006, pp. 1444-9.
Howden NS, Zyczynski HM, Moalli PA, et al. Comparison of autologous rectus fascia and cadaveric fascia in pubovaginal sling continence outcomes. Am J Obstet Gynecol. 2006;194(5):1444-9.
Howden, N. S., Zyczynski, H. M., Moalli, P. A., Sagan, E. R., Meyn, L. A., & Weber, A. M. (2006). Comparison of autologous rectus fascia and cadaveric fascia in pubovaginal sling continence outcomes. American Journal of Obstetrics and Gynecology, 194(5), 1444-9.
Howden NS, et al. Comparison of Autologous Rectus Fascia and Cadaveric Fascia in Pubovaginal Sling Continence Outcomes. Am J Obstet Gynecol. 2006;194(5):1444-9. PubMed PMID: 16579930.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of autologous rectus fascia and cadaveric fascia in pubovaginal sling continence outcomes. AU - Howden,Nancy S, AU - Zyczynski,Halina M, AU - Moalli,Pamela A, AU - Sagan,Elizabeth R, AU - Meyn,Leslie A, AU - Weber,Anne M, Y1 - 2006/03/31/ PY - 2005/06/24/received PY - 2005/11/17/revised PY - 2006/01/13/accepted PY - 2006/4/4/pubmed PY - 2006/6/2/medline PY - 2006/4/4/entrez SP - 1444 EP - 9 JF - American journal of obstetrics and gynecology JO - Am J Obstet Gynecol VL - 194 IS - 5 N2 - OBJECTIVE: The purpose of this study was to compare autologous versus cadaveric grafts in pubovaginal slings. STUDY DESIGN: Women who had pubovaginal slings from 1994 to 2003 completed history, questionnaires, prolapse staging, and cough stress testing. Failure was defined by recurrent urinary incontinence symptoms and reoperation for stress incontinence. Group differences were evaluated using Student t test or chi-square test. The log-rank test was used to evaluate time to failure between the groups. RESULTS: Of 303 women enrolled, 153 had autologous and 150 had cadaveric grafts. Regular urine leakage (39.6% vs 28.3%, P = .04) and reoperation for stress incontinence (12.7% vs 3.3%, P = .003) occurred more in the cadaveric versus autologous group, respectively. Adjusting for differing follow-up times, the cadaveric versus autologous group experienced higher rates of urinary incontinence (16 vs 5 per 100 women-years, P < .0001) and higher rates of reoperation (4 vs 1 per 100 women-years, P < .0003). CONCLUSION: Autologous grafts used in pubovaginal slings have superior continence outcomes compared with cadaveric fascia. SN - 1097-6868 UR - https://www.unboundmedicine.com/medline/citation/16579930/Comparison_of_autologous_rectus_fascia_and_cadaveric_fascia_in_pubovaginal_sling_continence_outcomes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9378(06)00098-6 DB - PRIME DP - Unbound Medicine ER -