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Evaluating the use of a Streptococcus pneumoniae urinary antigen detection kit for the management of community-acquired pneumonia in Japan.
Respiration. 2007; 74(4):387-93.R

Abstract

BACKGROUND

The urinary antigen detection kit for Streptococcus pneumoniae was tested.

OBJECTIVES

It was our aim to evaluate the usefulness of the immunochromatographic membrane test by doing a large prospective study of community-acquired pneumonia (CAP) in Japan.

METHODS

We prospectively evaluated the use of the S. pneumoniae urinary antigen detection kit and analyzed the treatment and clinical effect seen in patients with positive test kit results. One hundred and fifty-six patients with CAP admitted to our hospital between October 2001 and September 2003 were evaluated.

RESULTS

In 49% of these CAP patients, the causative microorganisms were isolated. S. pneumoniae was suspected to be the causative microorganism in 15%, but positive results of the urinary antigen detection kit indicated S. pneumoniae to be a probable microorganism in 28%, even though antibiotics had previously been administered to half of the patients. The kit was particularly useful for diagnosing patients with poor quality sputum in whom antibiotics treatment nevertheless had to be selected. Antibiotics appropriate for S. pneumoniae (mainly penicillin) were given. The treatment was found to have excellent clinical results in 89% of the CAP patients.

CONCLUSIONS

The S. pneumoniae urinary antigen detection kit was considered to be useful in selecting treatment since there was a high level of clinical effectiveness when the most suitable antibiotics were immediately administered to positive patients. The use of the S. pneumoniae urinary antigen kit is rapid and simple compared with conventional microbiological procedures.

Authors+Show Affiliations

Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashiki, Japan. yoshihiro@med.kawasaki-m.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16582535

Citation

Kobashi, Yoshihiro, et al. "Evaluating the Use of a Streptococcus Pneumoniae Urinary Antigen Detection Kit for the Management of Community-acquired Pneumonia in Japan." Respiration; International Review of Thoracic Diseases, vol. 74, no. 4, 2007, pp. 387-93.
Kobashi Y, Yoshida K, Miyashita N, et al. Evaluating the use of a Streptococcus pneumoniae urinary antigen detection kit for the management of community-acquired pneumonia in Japan. Respiration. 2007;74(4):387-93.
Kobashi, Y., Yoshida, K., Miyashita, N., Niki, Y., & Matsushima, T. (2007). Evaluating the use of a Streptococcus pneumoniae urinary antigen detection kit for the management of community-acquired pneumonia in Japan. Respiration; International Review of Thoracic Diseases, 74(4), 387-93.
Kobashi Y, et al. Evaluating the Use of a Streptococcus Pneumoniae Urinary Antigen Detection Kit for the Management of Community-acquired Pneumonia in Japan. Respiration. 2007;74(4):387-93. PubMed PMID: 16582535.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluating the use of a Streptococcus pneumoniae urinary antigen detection kit for the management of community-acquired pneumonia in Japan. AU - Kobashi,Yoshihiro, AU - Yoshida,Kouichiro, AU - Miyashita,Naoyuki, AU - Niki,Yoshihito, AU - Matsushima,Toshiharu, Y1 - 2006/03/19/ PY - 2005/08/15/received PY - 2005/12/19/accepted PY - 2006/4/4/pubmed PY - 2007/9/28/medline PY - 2006/4/4/entrez SP - 387 EP - 93 JF - Respiration; international review of thoracic diseases JO - Respiration VL - 74 IS - 4 N2 - BACKGROUND: The urinary antigen detection kit for Streptococcus pneumoniae was tested. OBJECTIVES: It was our aim to evaluate the usefulness of the immunochromatographic membrane test by doing a large prospective study of community-acquired pneumonia (CAP) in Japan. METHODS: We prospectively evaluated the use of the S. pneumoniae urinary antigen detection kit and analyzed the treatment and clinical effect seen in patients with positive test kit results. One hundred and fifty-six patients with CAP admitted to our hospital between October 2001 and September 2003 were evaluated. RESULTS: In 49% of these CAP patients, the causative microorganisms were isolated. S. pneumoniae was suspected to be the causative microorganism in 15%, but positive results of the urinary antigen detection kit indicated S. pneumoniae to be a probable microorganism in 28%, even though antibiotics had previously been administered to half of the patients. The kit was particularly useful for diagnosing patients with poor quality sputum in whom antibiotics treatment nevertheless had to be selected. Antibiotics appropriate for S. pneumoniae (mainly penicillin) were given. The treatment was found to have excellent clinical results in 89% of the CAP patients. CONCLUSIONS: The S. pneumoniae urinary antigen detection kit was considered to be useful in selecting treatment since there was a high level of clinical effectiveness when the most suitable antibiotics were immediately administered to positive patients. The use of the S. pneumoniae urinary antigen kit is rapid and simple compared with conventional microbiological procedures. SN - 0025-7931 UR - https://www.unboundmedicine.com/medline/citation/16582535/Evaluating_the_use_of_a_Streptococcus_pneumoniae_urinary_antigen_detection_kit_for_the_management_of_community_acquired_pneumonia_in_Japan_ L2 - https://www.karger.com?DOI=10.1159/000092547 DB - PRIME DP - Unbound Medicine ER -