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Diabetes and hypertension: a review.
Prim Care 1991; 18(3):509-24PC

Abstract

The basic mechanisms that initiate and sustain hypertension in type 2 diabetics are poorly understood. Contributing factors discussed in this review include obesity, insulin resistance, hyperinsulinemia, genetic factors, and abnormalities of cellular cation homeostasis. Also discussed are the features of hypertension in type 2 diabetic individuals that are reminiscent of the hemodynamic abnormalities characterizing hypertension in the elderly, including increased vascular reactivity and increased atherosclerotic vascular disease. This article reviews mechanisms by which hyperinsulinemia, insulin resistance, or both may lead to hypertension.

Authors+Show Affiliations

Division of Endocrinology, Wayne State University School of Medicine, Detroit, Michigan.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

1658839

Citation

Sowers, J R., and S Khoury. "Diabetes and Hypertension: a Review." Primary Care, vol. 18, no. 3, 1991, pp. 509-24.
Sowers JR, Khoury S. Diabetes and hypertension: a review. Prim Care. 1991;18(3):509-24.
Sowers, J. R., & Khoury, S. (1991). Diabetes and hypertension: a review. Primary Care, 18(3), pp. 509-24.
Sowers JR, Khoury S. Diabetes and Hypertension: a Review. Prim Care. 1991;18(3):509-24. PubMed PMID: 1658839.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diabetes and hypertension: a review. AU - Sowers,J R, AU - Khoury,S, PY - 1991/9/1/pubmed PY - 1991/9/1/medline PY - 1991/9/1/entrez SP - 509 EP - 24 JF - Primary care JO - Prim. Care VL - 18 IS - 3 N2 - The basic mechanisms that initiate and sustain hypertension in type 2 diabetics are poorly understood. Contributing factors discussed in this review include obesity, insulin resistance, hyperinsulinemia, genetic factors, and abnormalities of cellular cation homeostasis. Also discussed are the features of hypertension in type 2 diabetic individuals that are reminiscent of the hemodynamic abnormalities characterizing hypertension in the elderly, including increased vascular reactivity and increased atherosclerotic vascular disease. This article reviews mechanisms by which hyperinsulinemia, insulin resistance, or both may lead to hypertension. SN - 0095-4543 UR - https://www.unboundmedicine.com/medline/citation/1658839/Diabetes_and_hypertension:_a_review_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -