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Anti-inflammatory and anti-nociceptive activities of Pluchea quitoc (DC.) ethanolic extract.
J Ethnopharmacol. 2006 Jul 19; 106(3):317-20.JE

Abstract

Pluchea quitoc DC. (Asteraceae), a plant widely distributed throughout Brazil and popularly known as "quitoco", "madre-cravo" or "tabacarana", is used in traditional medicine for the treatment of inflammation, as well as of digestive and respiratory diseases. The anti-inflammatory and anti-nociceptive activities of the ethanolic extract (EE) from aerial parts of this plant were evaluated in mice and rats. Oral treatment with the EE (1-2g/kg, p.o.) decreased the paw oedema induced by carrageenan in rats, showed anti-nociceptive effects on the tail-flick test and on acid-induced writhing in mice, and inhibited both phases of pain (neurogenic and inflammatory) of the formalin test in rats. Topical application (EE 1.25, 2.5 and 5.0mg) inhibited the ear oedema induced by croton oil in mice. The results support the folkloric use of the plant in inflammatory processes.

Authors+Show Affiliations

Departamento de Ciências Fisiológicas, Universidade Federal do Maranhão (UFMA), Av. dos Portugueses, s/n, Campus do Bacanga, 65085-580 São Luís, Maranhão, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16600542

Citation

Barros, I M C., et al. "Anti-inflammatory and Anti-nociceptive Activities of Pluchea Quitoc (DC.) Ethanolic Extract." Journal of Ethnopharmacology, vol. 106, no. 3, 2006, pp. 317-20.
Barros IM, Lopes LD, Borges MO, et al. Anti-inflammatory and anti-nociceptive activities of Pluchea quitoc (DC.) ethanolic extract. J Ethnopharmacol. 2006;106(3):317-20.
Barros, I. M., Lopes, L. D., Borges, M. O., Borges, A. C., Ribeiro, M. N., & Freire, S. M. (2006). Anti-inflammatory and anti-nociceptive activities of Pluchea quitoc (DC.) ethanolic extract. Journal of Ethnopharmacology, 106(3), 317-20.
Barros IM, et al. Anti-inflammatory and Anti-nociceptive Activities of Pluchea Quitoc (DC.) Ethanolic Extract. J Ethnopharmacol. 2006 Jul 19;106(3):317-20. PubMed PMID: 16600542.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-inflammatory and anti-nociceptive activities of Pluchea quitoc (DC.) ethanolic extract. AU - Barros,I M C, AU - Lopes,L D G, AU - Borges,M O R, AU - Borges,A C R, AU - Ribeiro,M N S, AU - Freire,S M F, Y1 - 2006/04/04/ PY - 2003/10/15/received PY - 2005/12/19/revised PY - 2006/01/13/accepted PY - 2006/4/8/pubmed PY - 2006/8/31/medline PY - 2006/4/8/entrez SP - 317 EP - 20 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 106 IS - 3 N2 - Pluchea quitoc DC. (Asteraceae), a plant widely distributed throughout Brazil and popularly known as "quitoco", "madre-cravo" or "tabacarana", is used in traditional medicine for the treatment of inflammation, as well as of digestive and respiratory diseases. The anti-inflammatory and anti-nociceptive activities of the ethanolic extract (EE) from aerial parts of this plant were evaluated in mice and rats. Oral treatment with the EE (1-2g/kg, p.o.) decreased the paw oedema induced by carrageenan in rats, showed anti-nociceptive effects on the tail-flick test and on acid-induced writhing in mice, and inhibited both phases of pain (neurogenic and inflammatory) of the formalin test in rats. Topical application (EE 1.25, 2.5 and 5.0mg) inhibited the ear oedema induced by croton oil in mice. The results support the folkloric use of the plant in inflammatory processes. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/16600542/Anti_inflammatory_and_anti_nociceptive_activities_of_Pluchea_quitoc__DC___ethanolic_extract_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0378-8741(06)00045-6 DB - PRIME DP - Unbound Medicine ER -