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Clinical and laboratory aspects of a trichinellosis outbreak in Izmir, Turkey.
Parasite 2006; 13(1):65-70P

Abstract

Epidemiological, clinical and laboratory data were collected during an outbreak of trichinellosis, which occurred in Izmir, Turkey, between January and March 2004. The source of the infection was raw meatballs made with a mixture of uncooked beef and pork. Of 474 persons who were admitted at the Ataturk Training and Research Hospital during this period with a history of raw meatball consumption, the diagnosis of trichinellosis was confirmed for 154 (32.5%, 87 males and 67 females; mean age 31 years, range 6-67 years). Among persons with a confirmed diagnosis, 79% had myalgia, 77% weakness and malaise, 63% arthralgia, 40% jaw pain, 68% fever, 63% periorbital and/or facial oedema, 49% oedema at the trunk and limb, 42% abdominal pain, 40% nausea and vomiting, 28% diarrhoea, 23% subconjunctival haemorrhage, 25% macular or petechial rash, 4% subungual haemorrhage, 15% cardiac complaints and 0.2% neurological complaints. Nine patients (5.8%) were hospitalised due to severe myalgia (n = 2), high fever (n = 3), neurological manifestations (n = 1), thrombophlebitis (n = 2) and palmar erythema (n = 1). Eosinophilia was present in 88% of the confirmed cases at the admission. Elevated levels of serum creatine phosphokinase, lactic dehydrogenase and aspartate aminotransferase were detected in 72%, 70% and 16% of the confirmed cases, respectively. The seroconversion occurred in most of the infected people between the 4th and 6th weeks after the infection. All of the confirmed cases were treated with mebendazole. People with severe symptoms were treated also with prednisolone (60 mg/day for three days) and those with a moderately severe clinical pattern received a non-steroid anti-inflammatory drug (naproxen sodium, 550 mg/day). All confirmed cases recovered without any clinical sequela.

Authors+Show Affiliations

Laboratory of Clinical Microbiology, Atatürk Training and Research Hospital, Izmir, Turkey. turkmeral@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16605069

Citation

Turk, M, et al. "Clinical and Laboratory Aspects of a Trichinellosis Outbreak in Izmir, Turkey." Parasite (Paris, France), vol. 13, no. 1, 2006, pp. 65-70.
Turk M, Kaptan F, Turker N, et al. Clinical and laboratory aspects of a trichinellosis outbreak in Izmir, Turkey. Parasite. 2006;13(1):65-70.
Turk, M., Kaptan, F., Turker, N., Korkmaz, M., El, S., Ozkaya, D., ... Pozio, E. (2006). Clinical and laboratory aspects of a trichinellosis outbreak in Izmir, Turkey. Parasite (Paris, France), 13(1), pp. 65-70.
Turk M, et al. Clinical and Laboratory Aspects of a Trichinellosis Outbreak in Izmir, Turkey. Parasite. 2006;13(1):65-70. PubMed PMID: 16605069.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical and laboratory aspects of a trichinellosis outbreak in Izmir, Turkey. AU - Turk,M, AU - Kaptan,F, AU - Turker,N, AU - Korkmaz,M, AU - El,S, AU - Ozkaya,D, AU - Ural,S, AU - Vardar,I, AU - Alkan,M Z, AU - Coskun,N A, AU - Turker,M, AU - Pozio,E, PY - 2006/4/12/pubmed PY - 2006/6/9/medline PY - 2006/4/12/entrez SP - 65 EP - 70 JF - Parasite (Paris, France) JO - Parasite VL - 13 IS - 1 N2 - Epidemiological, clinical and laboratory data were collected during an outbreak of trichinellosis, which occurred in Izmir, Turkey, between January and March 2004. The source of the infection was raw meatballs made with a mixture of uncooked beef and pork. Of 474 persons who were admitted at the Ataturk Training and Research Hospital during this period with a history of raw meatball consumption, the diagnosis of trichinellosis was confirmed for 154 (32.5%, 87 males and 67 females; mean age 31 years, range 6-67 years). Among persons with a confirmed diagnosis, 79% had myalgia, 77% weakness and malaise, 63% arthralgia, 40% jaw pain, 68% fever, 63% periorbital and/or facial oedema, 49% oedema at the trunk and limb, 42% abdominal pain, 40% nausea and vomiting, 28% diarrhoea, 23% subconjunctival haemorrhage, 25% macular or petechial rash, 4% subungual haemorrhage, 15% cardiac complaints and 0.2% neurological complaints. Nine patients (5.8%) were hospitalised due to severe myalgia (n = 2), high fever (n = 3), neurological manifestations (n = 1), thrombophlebitis (n = 2) and palmar erythema (n = 1). Eosinophilia was present in 88% of the confirmed cases at the admission. Elevated levels of serum creatine phosphokinase, lactic dehydrogenase and aspartate aminotransferase were detected in 72%, 70% and 16% of the confirmed cases, respectively. The seroconversion occurred in most of the infected people between the 4th and 6th weeks after the infection. All of the confirmed cases were treated with mebendazole. People with severe symptoms were treated also with prednisolone (60 mg/day for three days) and those with a moderately severe clinical pattern received a non-steroid anti-inflammatory drug (naproxen sodium, 550 mg/day). All confirmed cases recovered without any clinical sequela. SN - 1252-607X UR - https://www.unboundmedicine.com/medline/citation/16605069/Clinical_and_laboratory_aspects_of_a_trichinellosis_outbreak_in_Izmir_Turkey_ L2 - http://publications.edpsciences.org/10.1051/parasite/2006131065 DB - PRIME DP - Unbound Medicine ER -