Tags

Type your tag names separated by a space and hit enter

Retinal injury thresholds for blue wavelength lasers.
Health Phys 2006; 90(5):477-84HP

Abstract

The interaction mechanism leading to laser-induced retinal alteration can be thermal or non-thermal, depending upon the wavelength of the laser radiation and the duration of the exposure. To investigate the effect of exposure duration on the interaction mechanism, retinal injury thresholds in the rhesus monkey were experimentally measured for exposure to laser radiation at wavelengths of 441.6, 457.9, 476.5, and 496.5 nm. Exposure durations were 0.1, 1, 5, 16, and 100 s; and 1/e retinal irradiance diameters were 50, 125, and 327 microm. Tissue response was observed via ophthalmoscope 1 h and 48 h post exposure. Thermal and non-thermal damage thresholds were obtained depending upon the exposure duration. These threshold data are in agreement with data previously reported in the literature for 100-s duration exposures, but differences were noted for shorter exposures. The current study yielded an estimated injury threshold for 1-s duration, 327-microm retinal irradiance diameter exposures at 441.6 nm, which is an order of magnitude higher than that previously reported. This study provides evidence that laser-induced retinal damage is primarily induced via thermal mechanisms for exposures shorter than 5 s in duration. Arguments are presented that support an amendment of the thermal hazard function, R(lambda).

Authors+Show Affiliations

U.S. Army Medical Research Detachment, Walter Reed Army Institute of Research, 7965 Dave Erwin Drive, Brooks City-Base, TX 78235-5108, USA. jack.lund@brooks.af.milNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16607179

Citation

Lund, David J., et al. "Retinal Injury Thresholds for Blue Wavelength Lasers." Health Physics, vol. 90, no. 5, 2006, pp. 477-84.
Lund DJ, Stuck BE, Edsall P. Retinal injury thresholds for blue wavelength lasers. Health Phys. 2006;90(5):477-84.
Lund, D. J., Stuck, B. E., & Edsall, P. (2006). Retinal injury thresholds for blue wavelength lasers. Health Physics, 90(5), pp. 477-84.
Lund DJ, Stuck BE, Edsall P. Retinal Injury Thresholds for Blue Wavelength Lasers. Health Phys. 2006;90(5):477-84. PubMed PMID: 16607179.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Retinal injury thresholds for blue wavelength lasers. AU - Lund,David J, AU - Stuck,Bruce E, AU - Edsall,Peter, PY - 2006/4/12/pubmed PY - 2006/5/11/medline PY - 2006/4/12/entrez SP - 477 EP - 84 JF - Health physics JO - Health Phys VL - 90 IS - 5 N2 - The interaction mechanism leading to laser-induced retinal alteration can be thermal or non-thermal, depending upon the wavelength of the laser radiation and the duration of the exposure. To investigate the effect of exposure duration on the interaction mechanism, retinal injury thresholds in the rhesus monkey were experimentally measured for exposure to laser radiation at wavelengths of 441.6, 457.9, 476.5, and 496.5 nm. Exposure durations were 0.1, 1, 5, 16, and 100 s; and 1/e retinal irradiance diameters were 50, 125, and 327 microm. Tissue response was observed via ophthalmoscope 1 h and 48 h post exposure. Thermal and non-thermal damage thresholds were obtained depending upon the exposure duration. These threshold data are in agreement with data previously reported in the literature for 100-s duration exposures, but differences were noted for shorter exposures. The current study yielded an estimated injury threshold for 1-s duration, 327-microm retinal irradiance diameter exposures at 441.6 nm, which is an order of magnitude higher than that previously reported. This study provides evidence that laser-induced retinal damage is primarily induced via thermal mechanisms for exposures shorter than 5 s in duration. Arguments are presented that support an amendment of the thermal hazard function, R(lambda). SN - 0017-9078 UR - https://www.unboundmedicine.com/medline/citation/16607179/Retinal_injury_thresholds_for_blue_wavelength_lasers_ L2 - http://Insights.ovid.com/pubmed?pmid=16607179 DB - PRIME DP - Unbound Medicine ER -