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[The course of gastroesophageal reflux disease in elderly patients with concomitant ischemic heart disease].
Ter Arkh. 2006; 78(2):42-5.TA

Abstract

AIM

To study basic functional and pathogenetic features of the course of gastroesophageal reflux disease (GERD) in elderly patients with concomitant coronary heart disease (CHD).

MATERIAL AND METHODS

Esophagogastroduodenoscopy, 24-h pH-metry, simultaneous 24-h pH- and ECG-monitoring, omeprasol test were made in 126 patients: 74 GERD patients with CHD and 52 patients with GERD alone.

RESULTS

Mean number of refluxes for 24 hours in isolated GERD was maximal at stages IIa and IIb (74%). In CHD patients (77%) there was a trend to a rise in this number. Only patients with associated CHD demonstrated a clinically significant depression of ST segment related to reflux, a significantly more frequent occurrence of supraventricular and ventricular extrasystoles.

CONCLUSION

The acid component of gastric content pushed into the esophagus is not a leading factor of esophageal mucosa lesion in GERD patients with CHD. Pathological gastroesophageal refluxes may trigger mechanisms provoking new attacks of angina pectoris.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

16613096

Citation

Zvenigorodskaia, L A., and Iu V. Taranchenko. "[The Course of Gastroesophageal Reflux Disease in Elderly Patients With Concomitant Ischemic Heart Disease]." Terapevticheskii Arkhiv, vol. 78, no. 2, 2006, pp. 42-5.
Zvenigorodskaia LA, Taranchenko IuV. [The course of gastroesophageal reflux disease in elderly patients with concomitant ischemic heart disease]. Ter Arkh. 2006;78(2):42-5.
Zvenigorodskaia, L. A., & Taranchenko, I. u. V. (2006). [The course of gastroesophageal reflux disease in elderly patients with concomitant ischemic heart disease]. Terapevticheskii Arkhiv, 78(2), 42-5.
Zvenigorodskaia LA, Taranchenko IuV. [The Course of Gastroesophageal Reflux Disease in Elderly Patients With Concomitant Ischemic Heart Disease]. Ter Arkh. 2006;78(2):42-5. PubMed PMID: 16613096.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The course of gastroesophageal reflux disease in elderly patients with concomitant ischemic heart disease]. AU - Zvenigorodskaia,L A, AU - Taranchenko,Iu V, PY - 2006/4/15/pubmed PY - 2006/5/4/medline PY - 2006/4/15/entrez SP - 42 EP - 5 JF - Terapevticheskii arkhiv JO - Ter. Arkh. VL - 78 IS - 2 N2 - AIM: To study basic functional and pathogenetic features of the course of gastroesophageal reflux disease (GERD) in elderly patients with concomitant coronary heart disease (CHD). MATERIAL AND METHODS: Esophagogastroduodenoscopy, 24-h pH-metry, simultaneous 24-h pH- and ECG-monitoring, omeprasol test were made in 126 patients: 74 GERD patients with CHD and 52 patients with GERD alone. RESULTS: Mean number of refluxes for 24 hours in isolated GERD was maximal at stages IIa and IIb (74%). In CHD patients (77%) there was a trend to a rise in this number. Only patients with associated CHD demonstrated a clinically significant depression of ST segment related to reflux, a significantly more frequent occurrence of supraventricular and ventricular extrasystoles. CONCLUSION: The acid component of gastric content pushed into the esophagus is not a leading factor of esophageal mucosa lesion in GERD patients with CHD. Pathological gastroesophageal refluxes may trigger mechanisms provoking new attacks of angina pectoris. SN - 0040-3660 UR - https://www.unboundmedicine.com/medline/citation/16613096/[The_course_of_gastroesophageal_reflux_disease_in_elderly_patients_with_concomitant_ischemic_heart_disease]_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -