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The glycemic load estimated from the glycemic index does not differ greatly from that measured using a standard curve in healthy volunteers.
J Nutr. 2006 May; 136(5):1377-81.JN

Abstract

Glycemic load (GL) is calculated indirectly as glycemic index (GI) times the weight of available carbohydrate. Alternatively, GL may be measured directly using a standard glucose curve. The purpose of this study was to test the agreement between GL values obtained using direct and indirect methods of measurement in 20 healthy volunteers. A standard curve in which glucose dose was plotted against blood glucose incremental area under the curve (iAUC) was generated using beverages containing 0, 12.5, 25, 50, and 75 g glucose. The GI and available carbohydrate content of 5 foods were measured. The foods (white bread, fruit bread, granola bar, instant potato, and chickpeas) were consumed in 3 portion sizes, yielding 15 food/portion size combinations. GL was determined directly by relating the iAUC of a test food to the glucose standard curve. For 12 of 15 food/portion size combinations, GL determined using GI x available carbohydrate did not differ from GL measured from the standard curve (P > 0.05). For 3 of the test products (100 g white bread, and 100- and 150-g granola bars), GI x available carbohydrate was higher than the direct measure. Benefits of the direct measure are that the method does not require testing for available carbohydrate and it allows portion sizes to be tested. For practical purposes, GI x available carbohydrate provided a good estimate of GL, at least under circumstances in which available carbohydrate was measured, and GI and GL were tested in the same group of people.

Authors+Show Affiliations

Venn BJ
Christchurch School of Medicine, University of Otago, Christchurch, New Zealand. bernard.venn@stonebow.otago.ac.nz
Wallace AJ
No affiliation info available
Monro JA
No affiliation info available
Perry T
No affiliation info available
Brown R
No affiliation info available
Frampton C
No affiliation info available
Green TJ
No affiliation info available

MeSH

Blood GlucoseBreadCicerDietary CarbohydratesFemaleGlycemic IndexHumansMaleReference ValuesReproducibility of ResultsSolanum tuberosum

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16614433

Citation

Venn, Bernard J., et al. "The Glycemic Load Estimated From the Glycemic Index Does Not Differ Greatly From That Measured Using a Standard Curve in Healthy Volunteers." The Journal of Nutrition, vol. 136, no. 5, 2006, pp. 1377-81.
Venn BJ, Wallace AJ, Monro JA, et al. The glycemic load estimated from the glycemic index does not differ greatly from that measured using a standard curve in healthy volunteers. J Nutr. 2006;136(5):1377-81.
Venn, B. J., Wallace, A. J., Monro, J. A., Perry, T., Brown, R., Frampton, C., & Green, T. J. (2006). The glycemic load estimated from the glycemic index does not differ greatly from that measured using a standard curve in healthy volunteers. The Journal of Nutrition, 136(5), 1377-81.
Venn BJ, et al. The Glycemic Load Estimated From the Glycemic Index Does Not Differ Greatly From That Measured Using a Standard Curve in Healthy Volunteers. J Nutr. 2006;136(5):1377-81. PubMed PMID: 16614433.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The glycemic load estimated from the glycemic index does not differ greatly from that measured using a standard curve in healthy volunteers. AU - Venn,Bernard J, AU - Wallace,Alison J, AU - Monro,John A, AU - Perry,Tracy, AU - Brown,Rachel, AU - Frampton,Chris, AU - Green,Tim J, PY - 2006/4/15/pubmed PY - 2006/6/24/medline PY - 2006/4/15/entrez SP - 1377 EP - 81 JF - The Journal of nutrition JO - J Nutr VL - 136 IS - 5 N2 - Glycemic load (GL) is calculated indirectly as glycemic index (GI) times the weight of available carbohydrate. Alternatively, GL may be measured directly using a standard glucose curve. The purpose of this study was to test the agreement between GL values obtained using direct and indirect methods of measurement in 20 healthy volunteers. A standard curve in which glucose dose was plotted against blood glucose incremental area under the curve (iAUC) was generated using beverages containing 0, 12.5, 25, 50, and 75 g glucose. The GI and available carbohydrate content of 5 foods were measured. The foods (white bread, fruit bread, granola bar, instant potato, and chickpeas) were consumed in 3 portion sizes, yielding 15 food/portion size combinations. GL was determined directly by relating the iAUC of a test food to the glucose standard curve. For 12 of 15 food/portion size combinations, GL determined using GI x available carbohydrate did not differ from GL measured from the standard curve (P > 0.05). For 3 of the test products (100 g white bread, and 100- and 150-g granola bars), GI x available carbohydrate was higher than the direct measure. Benefits of the direct measure are that the method does not require testing for available carbohydrate and it allows portion sizes to be tested. For practical purposes, GI x available carbohydrate provided a good estimate of GL, at least under circumstances in which available carbohydrate was measured, and GI and GL were tested in the same group of people. SN - 0022-3166 UR - https://www.unboundmedicine.com/medline/citation/16614433/The_glycemic_load_estimated_from_the_glycemic_index_does_not_differ_greatly_from_that_measured_using_a_standard_curve_in_healthy_volunteers_ DB - PRIME DP - Unbound Medicine ER -