Tags

Type your tag names separated by a space and hit enter

Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort study.

Abstract

Although there is little evidence to support an association between alcohol consumption and prostate cancer risk, questions remain concerning the effect on aggressive and nonaggressive tumours and the pattern and type of alcohol consumed. In a prospective cohort of 16,872 men aged 27-70 years at recruitment and followed-up from 1994 to the end of 2003, 732 incident prostate cancers were identified through the local population cancer registry, including 132 aggressive cases and 53 prostate cancer deaths. Detailed information on alcohol consumption was taken at baseline by trained interviewers using a structured questionnaire. Overall, alcohol intake was not associated with prostate cancer incidence. Compared to abstainers, men consuming 1-19 g/d of alcohol had a slightly reduced incidence of aggressive prostate cancers (hazard ratio 0.67; 95% confidence interval (CI) 0.43, 1.06) and prostate cancer mortality (hazard ratio 0.56; 95% CI 0.28, 1.14), but their risk of nonaggressive prostate cancers was close to unity (hazard ratio 1.09; 95% CI 0.85, 1.40). No significant association with pattern of drinking or type of alcoholic beverage was found. Our results show that alcohol consumption does not influence overall prostate cancer incidence but we found suggestive evidence that alcohol consumption might decrease the incidence of aggressive prostate cancer and mortality.

Links

  • FREE Publisher Full Text
  • Authors+Show Affiliations

    ,

    Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, VIC, Australia.

    , , ,

    Source

    International journal of cancer 119:6 2006 Sep 15 pg 1501-4

    MeSH

    Adult
    Aged
    Alcohol Drinking
    Australia
    Cohort Studies
    Humans
    Incidence
    Male
    Middle Aged
    Prospective Studies
    Prostatic Neoplasms
    Risk Factors
    Surveys and Questionnaires

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    16615108

    Citation

    Baglietto, Laura, et al. "Alcohol Consumption and Prostate Cancer Risk: Results From the Melbourne Collaborative Cohort Study." International Journal of Cancer, vol. 119, no. 6, 2006, pp. 1501-4.
    Baglietto L, Severi G, English DR, et al. Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort study. Int J Cancer. 2006;119(6):1501-4.
    Baglietto, L., Severi, G., English, D. R., Hopper, J. L., & Giles, G. G. (2006). Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort study. International Journal of Cancer, 119(6), pp. 1501-4.
    Baglietto L, et al. Alcohol Consumption and Prostate Cancer Risk: Results From the Melbourne Collaborative Cohort Study. Int J Cancer. 2006 Sep 15;119(6):1501-4. PubMed PMID: 16615108.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Alcohol consumption and prostate cancer risk: results from the Melbourne collaborative cohort study. AU - Baglietto,Laura, AU - Severi,Gianluca, AU - English,Dallas R, AU - Hopper,John L, AU - Giles,Graham G, PY - 2006/4/15/pubmed PY - 2006/9/13/medline PY - 2006/4/15/entrez SP - 1501 EP - 4 JF - International journal of cancer JO - Int. J. Cancer VL - 119 IS - 6 N2 - Although there is little evidence to support an association between alcohol consumption and prostate cancer risk, questions remain concerning the effect on aggressive and nonaggressive tumours and the pattern and type of alcohol consumed. In a prospective cohort of 16,872 men aged 27-70 years at recruitment and followed-up from 1994 to the end of 2003, 732 incident prostate cancers were identified through the local population cancer registry, including 132 aggressive cases and 53 prostate cancer deaths. Detailed information on alcohol consumption was taken at baseline by trained interviewers using a structured questionnaire. Overall, alcohol intake was not associated with prostate cancer incidence. Compared to abstainers, men consuming 1-19 g/d of alcohol had a slightly reduced incidence of aggressive prostate cancers (hazard ratio 0.67; 95% confidence interval (CI) 0.43, 1.06) and prostate cancer mortality (hazard ratio 0.56; 95% CI 0.28, 1.14), but their risk of nonaggressive prostate cancers was close to unity (hazard ratio 1.09; 95% CI 0.85, 1.40). No significant association with pattern of drinking or type of alcoholic beverage was found. Our results show that alcohol consumption does not influence overall prostate cancer incidence but we found suggestive evidence that alcohol consumption might decrease the incidence of aggressive prostate cancer and mortality. SN - 0020-7136 UR - https://www.unboundmedicine.com/medline/citation/16615108/Alcohol_consumption_and_prostate_cancer_risk:_results_from_the_Melbourne_collaborative_cohort_study_ L2 - https://doi.org/10.1002/ijc.21983 DB - PRIME DP - Unbound Medicine ER -