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Effects of pollution on human growth and development: an introduction.
J Physiol Anthropol 2006; 25(1):103-12JP

Abstract

Pollution is a worldwide problem and its potential to influence the physiology of human populations is great. Studies of human growth and development in relation to pollution have increased in number and quality since the mid-twentieth century. Many studies have found that some pollutants have detrimental effects on human growth, particularly prenatal growth. The heavy metal, lead, is commonly found in human populations and is related to smaller size at birth and studies have reported decrements that range up to about 200 grams. Noise stress from transportation sources also is related to reduced prenatal growth with somewhat smaller decrements reported. Studies of humans exposed to polychlorinated biphenyls, one of the persistent organic pollutants, have reduced size at birth, advanced sexual maturation and altered hormone levels related to thyroid regulation. Thus different pollutants exert effects through different physiological pathways. However, some studies have not observed these effects, which indicates that the situation is complex and requires further study with better study designs. Determining the effects of pollutants on human physiology and growth is difficult as it requires fairly large numbers of subjects who are not purposely exposed but for whom exposure can be measured. These effects of pollutants and the mechanisms of effect require further study to understand and, it is hoped, to blunt or block any detrimental effects on human health and well-being.

Authors+Show Affiliations

University at Albany, Albany, NY 12222, USA l.schell@albany.edu.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16617215

Citation

Schell, Lawrence M., et al. "Effects of Pollution On Human Growth and Development: an Introduction." Journal of Physiological Anthropology, vol. 25, no. 1, 2006, pp. 103-12.
Schell LM, Gallo MV, Denham M, et al. Effects of pollution on human growth and development: an introduction. J Physiol Anthropol. 2006;25(1):103-12.
Schell, L. M., Gallo, M. V., Denham, M., & Ravenscroft, J. (2006). Effects of pollution on human growth and development: an introduction. Journal of Physiological Anthropology, 25(1), pp. 103-12.
Schell LM, et al. Effects of Pollution On Human Growth and Development: an Introduction. J Physiol Anthropol. 2006;25(1):103-12. PubMed PMID: 16617215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of pollution on human growth and development: an introduction. AU - Schell,Lawrence M, AU - Gallo,Mia V, AU - Denham,Melinda, AU - Ravenscroft,Julia, PY - 2006/4/18/pubmed PY - 2006/6/29/medline PY - 2006/4/18/entrez SP - 103 EP - 12 JF - Journal of physiological anthropology JO - J Physiol Anthropol VL - 25 IS - 1 N2 - Pollution is a worldwide problem and its potential to influence the physiology of human populations is great. Studies of human growth and development in relation to pollution have increased in number and quality since the mid-twentieth century. Many studies have found that some pollutants have detrimental effects on human growth, particularly prenatal growth. The heavy metal, lead, is commonly found in human populations and is related to smaller size at birth and studies have reported decrements that range up to about 200 grams. Noise stress from transportation sources also is related to reduced prenatal growth with somewhat smaller decrements reported. Studies of humans exposed to polychlorinated biphenyls, one of the persistent organic pollutants, have reduced size at birth, advanced sexual maturation and altered hormone levels related to thyroid regulation. Thus different pollutants exert effects through different physiological pathways. However, some studies have not observed these effects, which indicates that the situation is complex and requires further study with better study designs. Determining the effects of pollutants on human physiology and growth is difficult as it requires fairly large numbers of subjects who are not purposely exposed but for whom exposure can be measured. These effects of pollutants and the mechanisms of effect require further study to understand and, it is hoped, to blunt or block any detrimental effects on human health and well-being. SN - 1880-6791 UR - https://www.unboundmedicine.com/medline/citation/16617215/full_citation L2 - http://joi.jlc.jst.go.jp/JST.JSTAGE/jpa2/25.103?from=PubMed DB - PRIME DP - Unbound Medicine ER -