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The recovery of illicit drugs from oral fluid sampling devices.
Forensic Sci Int. 2007 Jan 05; 165(1):78-84.FS

Abstract

Testing for drugs in oral fluid is a convenient procedure for determining recent drug use. A number of issues are still to be resolved and this paper investigates the effects of storage systems on drug stability and recovery using three different collection devices supplied by Cozart, Immunalysis and Microgenics (third party). Drugs were analysed using a range of immunoassay systems followed by MS confirmation and quantitation. The reproducibility of the weight of specimen collected was excellent (CV<10%) for the three collection devices tested. Of the three systems studied, only the Cozart product gave acceptable recovery of THC from drug-spiked oral fluid. A combination of Cozart, Immunalysis and Diagnostix immunoassays with the Cozart collection system gave the most sensitive and discriminating screening assays for the drugs studied, namely THC, benzodiazepines, methamphetamine and morphine. Storage at either 5 degrees C or room temperature had no significant effect on drug recoveries.

Authors+Show Affiliations

Institute of Environmental Science and Research Ltd., Kenepuru Science Centre, PO Box 50 348, Porirua, New Zealand. stuart.dickson@esr.cri.nzNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16621382

Citation

Dickson, Stuart, et al. "The Recovery of Illicit Drugs From Oral Fluid Sampling Devices." Forensic Science International, vol. 165, no. 1, 2007, pp. 78-84.
Dickson S, Park A, Nolan S, et al. The recovery of illicit drugs from oral fluid sampling devices. Forensic Sci Int. 2007;165(1):78-84.
Dickson, S., Park, A., Nolan, S., Kenworthy, S., Nicholson, C., Midgley, J., Pinfold, R., & Hampton, S. (2007). The recovery of illicit drugs from oral fluid sampling devices. Forensic Science International, 165(1), 78-84.
Dickson S, et al. The Recovery of Illicit Drugs From Oral Fluid Sampling Devices. Forensic Sci Int. 2007 Jan 5;165(1):78-84. PubMed PMID: 16621382.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The recovery of illicit drugs from oral fluid sampling devices. AU - Dickson,Stuart, AU - Park,Alexandra, AU - Nolan,Susan, AU - Kenworthy,Sarah, AU - Nicholson,Cheryl, AU - Midgley,Julie, AU - Pinfold,Rowena, AU - Hampton,Scott, Y1 - 2006/04/18/ PY - 2005/11/25/received PY - 2006/03/03/revised PY - 2006/03/04/accepted PY - 2006/4/20/pubmed PY - 2007/3/7/medline PY - 2006/4/20/entrez SP - 78 EP - 84 JF - Forensic science international JO - Forensic Sci. Int. VL - 165 IS - 1 N2 - Testing for drugs in oral fluid is a convenient procedure for determining recent drug use. A number of issues are still to be resolved and this paper investigates the effects of storage systems on drug stability and recovery using three different collection devices supplied by Cozart, Immunalysis and Microgenics (third party). Drugs were analysed using a range of immunoassay systems followed by MS confirmation and quantitation. The reproducibility of the weight of specimen collected was excellent (CV<10%) for the three collection devices tested. Of the three systems studied, only the Cozart product gave acceptable recovery of THC from drug-spiked oral fluid. A combination of Cozart, Immunalysis and Diagnostix immunoassays with the Cozart collection system gave the most sensitive and discriminating screening assays for the drugs studied, namely THC, benzodiazepines, methamphetamine and morphine. Storage at either 5 degrees C or room temperature had no significant effect on drug recoveries. SN - 0379-0738 UR - https://www.unboundmedicine.com/medline/citation/16621382/The_recovery_of_illicit_drugs_from_oral_fluid_sampling_devices_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0379-0738(06)00138-1 DB - PRIME DP - Unbound Medicine ER -