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Montelukast in general pediatric practices.
J Med Assoc Thai. 2005 Sep; 88 Suppl 4:S348-51.JM

Abstract

Allergic diseases, e.g., allergic rhinitis, atopic dermatitis and asthma, are common problems in children. Researches on the pathogenesis of allergic diseases have led to the development of new specific antiinflammatory medications, including Montelukast, which blocks the interaction of cysteinyl leukotrienes to their receptors and resulting downstream events. Several studies have demonstrated the effect of regular Montelukast therapy on asthma, allergic rhinitis, viral-induced wheezing in bronchiolitis and chronic rhinitis symptoms. Evidence base medicine now shows that Montelukast can be used as a monotherapy in mild persistent asthma and can be an add-on drug to inhaled corticosteroid (ICS) in moderate to severe persistent asthma. Even in allergic rhinitis, Montelukast has a role in controlling rhinitis symptoms. Montelukast demonstrated a safety profile similar to placebo and more safety than ICS. Moreover Montelukast can improve quality of life in patients with asthma and comorbid allergic rhinitis.

Authors+Show Affiliations

Department of Pediatrics, Allergy and Immunology Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. ngamphaiboon_j@yahoo.com

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16623053

Citation

Ngamphaiboon, Jarungchit. "Montelukast in General Pediatric Practices." Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, vol. 88 Suppl 4, 2005, pp. S348-51.
Ngamphaiboon J. Montelukast in general pediatric practices. J Med Assoc Thai. 2005;88 Suppl 4:S348-51.
Ngamphaiboon, J. (2005). Montelukast in general pediatric practices. Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 88 Suppl 4, S348-51.
Ngamphaiboon J. Montelukast in General Pediatric Practices. J Med Assoc Thai. 2005;88 Suppl 4:S348-51. PubMed PMID: 16623053.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Montelukast in general pediatric practices. A1 - Ngamphaiboon,Jarungchit, PY - 2006/4/21/pubmed PY - 2006/5/27/medline PY - 2006/4/21/entrez SP - S348 EP - 51 JF - Journal of the Medical Association of Thailand = Chotmaihet thangphaet JO - J Med Assoc Thai VL - 88 Suppl 4 N2 - Allergic diseases, e.g., allergic rhinitis, atopic dermatitis and asthma, are common problems in children. Researches on the pathogenesis of allergic diseases have led to the development of new specific antiinflammatory medications, including Montelukast, which blocks the interaction of cysteinyl leukotrienes to their receptors and resulting downstream events. Several studies have demonstrated the effect of regular Montelukast therapy on asthma, allergic rhinitis, viral-induced wheezing in bronchiolitis and chronic rhinitis symptoms. Evidence base medicine now shows that Montelukast can be used as a monotherapy in mild persistent asthma and can be an add-on drug to inhaled corticosteroid (ICS) in moderate to severe persistent asthma. Even in allergic rhinitis, Montelukast has a role in controlling rhinitis symptoms. Montelukast demonstrated a safety profile similar to placebo and more safety than ICS. Moreover Montelukast can improve quality of life in patients with asthma and comorbid allergic rhinitis. SN - 0125-2208 UR - https://www.unboundmedicine.com/medline/citation/16623053/Montelukast_in_general_pediatric_practices_ L2 - https://medlineplus.gov/hayfever.html DB - PRIME DP - Unbound Medicine ER -