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Prevalence of the metabolic syndrome and its relation to cardiovascular disease in an elderly Chinese population.
J Am Coll Cardiol 2006; 47(8):1588-94JACC

Abstract

OBJECTIVES

This study sought to assess the prevalence of the metabolic syndrome (MetS) and its association with cardiovascular disease (CVD) in elderly Chinese people.

BACKGROUND

The information available about the prevalence of MetS based on the National Cholesterol Education Program (NCEP) and the International Diabetes Federation (IDF) in China is limited.

METHODS

We conducted a population-based cross-sectional study in an urban Beijing sample of 2,334 participants age 60 to 95 years (943 men, 1,391 women). The CVD included diagnosed coronary heart disease (CHD), stroke, and peripheral arterial disease (PAD).

RESULTS

The prevalence of MetS by the NCEP criteria was 30.5% (17.6% in men, 39.2% in women). Use of the new IDF definition significantly increased the prevalence to 46.3% (34.8% in men, 54.1% in women). Odds ratios (OR) for CHD, stroke, PAD, and CVD in those with MetS using the NCEP criteria were 1.43 (95% confidence interval [CI] 1.18 to 1.74), 1.45 (95% CI 1.14 to 1.85), 1.47 (95% CI 1.18 to 1.84), and 1.50 (95% CI 1.25 to 1.81), respectively. Corresponding ORs using new IDF criteria were 1.69 (95% CI 1.40 to 2.02), 1.58 (95% CI 1.26 to 2.00), 1.42 (95% CI 1.14 to 1.76), and 1.73 (95% CI 1.46 to 2.07), respectively. Those who met the IDF but not the NCEP criteria (n = 436, 18.7%) had significantly elevated ORs for CHD (1.66, 95% CI 1.31 to 2.10) and stroke (1.53, 95% CI 1.13 to 2.06).

CONCLUSIONS

The MetS is highly prevalent in elderly people in Beijing, particularly among women. Individuals with MetS defined by either criteria are at significantly elevated ORs for CHD, stroke, and PAD. The IDF criteria seem to be better suited than the NCEP criteria for screening and estimating risk of MetS in Chinese people.

Authors+Show Affiliations

Institute of Geriatrics, Chinese PLA General Hospital, Beijing, China. yhe301@x263.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16630995

Citation

He, Yao, et al. "Prevalence of the Metabolic Syndrome and Its Relation to Cardiovascular Disease in an Elderly Chinese Population." Journal of the American College of Cardiology, vol. 47, no. 8, 2006, pp. 1588-94.
He Y, Jiang B, Wang J, et al. Prevalence of the metabolic syndrome and its relation to cardiovascular disease in an elderly Chinese population. J Am Coll Cardiol. 2006;47(8):1588-94.
He, Y., Jiang, B., Wang, J., Feng, K., Chang, Q., Fan, L., ... Hu, F. B. (2006). Prevalence of the metabolic syndrome and its relation to cardiovascular disease in an elderly Chinese population. Journal of the American College of Cardiology, 47(8), pp. 1588-94.
He Y, et al. Prevalence of the Metabolic Syndrome and Its Relation to Cardiovascular Disease in an Elderly Chinese Population. J Am Coll Cardiol. 2006 Apr 18;47(8):1588-94. PubMed PMID: 16630995.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of the metabolic syndrome and its relation to cardiovascular disease in an elderly Chinese population. AU - He,Yao, AU - Jiang,Bin, AU - Wang,Jie, AU - Feng,Kang, AU - Chang,Qing, AU - Fan,Li, AU - Li,Xiaoying, AU - Hu,Frank B, Y1 - 2006/03/29/ PY - 2005/09/27/received PY - 2005/11/23/revised PY - 2005/11/28/accepted PY - 2006/4/25/pubmed PY - 2006/5/18/medline PY - 2006/4/25/entrez SP - 1588 EP - 94 JF - Journal of the American College of Cardiology JO - J. Am. Coll. Cardiol. VL - 47 IS - 8 N2 - OBJECTIVES: This study sought to assess the prevalence of the metabolic syndrome (MetS) and its association with cardiovascular disease (CVD) in elderly Chinese people. BACKGROUND: The information available about the prevalence of MetS based on the National Cholesterol Education Program (NCEP) and the International Diabetes Federation (IDF) in China is limited. METHODS: We conducted a population-based cross-sectional study in an urban Beijing sample of 2,334 participants age 60 to 95 years (943 men, 1,391 women). The CVD included diagnosed coronary heart disease (CHD), stroke, and peripheral arterial disease (PAD). RESULTS: The prevalence of MetS by the NCEP criteria was 30.5% (17.6% in men, 39.2% in women). Use of the new IDF definition significantly increased the prevalence to 46.3% (34.8% in men, 54.1% in women). Odds ratios (OR) for CHD, stroke, PAD, and CVD in those with MetS using the NCEP criteria were 1.43 (95% confidence interval [CI] 1.18 to 1.74), 1.45 (95% CI 1.14 to 1.85), 1.47 (95% CI 1.18 to 1.84), and 1.50 (95% CI 1.25 to 1.81), respectively. Corresponding ORs using new IDF criteria were 1.69 (95% CI 1.40 to 2.02), 1.58 (95% CI 1.26 to 2.00), 1.42 (95% CI 1.14 to 1.76), and 1.73 (95% CI 1.46 to 2.07), respectively. Those who met the IDF but not the NCEP criteria (n = 436, 18.7%) had significantly elevated ORs for CHD (1.66, 95% CI 1.31 to 2.10) and stroke (1.53, 95% CI 1.13 to 2.06). CONCLUSIONS: The MetS is highly prevalent in elderly people in Beijing, particularly among women. Individuals with MetS defined by either criteria are at significantly elevated ORs for CHD, stroke, and PAD. The IDF criteria seem to be better suited than the NCEP criteria for screening and estimating risk of MetS in Chinese people. SN - 1558-3597 UR - https://www.unboundmedicine.com/medline/citation/16630995/Prevalence_of_the_metabolic_syndrome_and_its_relation_to_cardiovascular_disease_in_an_elderly_Chinese_population_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0735-1097(06)00299-3 DB - PRIME DP - Unbound Medicine ER -