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Body composition and resting energy expenditure in elderly male patients with chronic obstructive pulmonary disease.
Respir Med. 2006 Nov; 100(11):1918-24.RM

Abstract

STUDY OBJECTIVE

Our study investigates nutritional status, resting energy expenditure (REE) and physical performance in elderly patients with stable COPD to identify any early conditions of hypermetabolism, malnutrition and sarcopenia.

METHODS

Eighty-six males (40 stable COPD and 46 healthy subjects) over 65 years old were studied. All subjects underwent spirometry, blood gas analysis and a 6-min walking test (6MWT). Fat-free mass (FFM) and appendicular skeletal muscle mass (ASMM) were measured by dual energy X-ray absorptiometry (DEXA). REE was measured by indirect calorimetry.

RESULTS

COPD patients had a lower FFM both expressed in kilograms and after correction for height squared. The prevalence of sarcopenia was higher for COPD subjects (38% vs 31%). REE, both in absolute values and adjusted for FFM was significantly higher in COPD patients. Hypermetabolism was found in 60% of COPD cases and 13.7% (P<0.01) of healthy subjects. No relationship was found in COPD patients between the measured/predicted REE ratio (REE(m)/REE(p)) and FEV1. In the hypermetabolic COPD subgroup, the REE(m)/REE(p) ratio correlated with 6MWT.

CONCLUSIONS

Elderly patients with stable COPD develop an increased REE. This hypermetabolism seems to be independent of the severity of the pulmonary obstruction and to influence the patient's physical performance.

Authors+Show Affiliations

Department of Medical and Surgical Sciences, Division of Geriatrics, University of Padua, Padua Italy. giuseppe.sergi@unipd.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16635565

Citation

Sergi, Giuseppe, et al. "Body Composition and Resting Energy Expenditure in Elderly Male Patients With Chronic Obstructive Pulmonary Disease." Respiratory Medicine, vol. 100, no. 11, 2006, pp. 1918-24.
Sergi G, Coin A, Marin S, et al. Body composition and resting energy expenditure in elderly male patients with chronic obstructive pulmonary disease. Respir Med. 2006;100(11):1918-24.
Sergi, G., Coin, A., Marin, S., Vianello, A., Manzan, A., Peruzza, S., Inelmen, E. M., Busetto, L., Mulone, S., & Enzi, G. (2006). Body composition and resting energy expenditure in elderly male patients with chronic obstructive pulmonary disease. Respiratory Medicine, 100(11), 1918-24.
Sergi G, et al. Body Composition and Resting Energy Expenditure in Elderly Male Patients With Chronic Obstructive Pulmonary Disease. Respir Med. 2006;100(11):1918-24. PubMed PMID: 16635565.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Body composition and resting energy expenditure in elderly male patients with chronic obstructive pulmonary disease. AU - Sergi,Giuseppe, AU - Coin,Alessandra, AU - Marin,Sara, AU - Vianello,Andrea, AU - Manzan,Alessandro, AU - Peruzza,Silvia, AU - Inelmen,Emine Meral, AU - Busetto,Luca, AU - Mulone,Silvana, AU - Enzi,Giuliano, Y1 - 2006/04/24/ PY - 2005/11/06/received PY - 2006/03/10/revised PY - 2006/03/10/accepted PY - 2006/4/26/pubmed PY - 2007/1/4/medline PY - 2006/4/26/entrez SP - 1918 EP - 24 JF - Respiratory medicine JO - Respir Med VL - 100 IS - 11 N2 - STUDY OBJECTIVE: Our study investigates nutritional status, resting energy expenditure (REE) and physical performance in elderly patients with stable COPD to identify any early conditions of hypermetabolism, malnutrition and sarcopenia. METHODS: Eighty-six males (40 stable COPD and 46 healthy subjects) over 65 years old were studied. All subjects underwent spirometry, blood gas analysis and a 6-min walking test (6MWT). Fat-free mass (FFM) and appendicular skeletal muscle mass (ASMM) were measured by dual energy X-ray absorptiometry (DEXA). REE was measured by indirect calorimetry. RESULTS: COPD patients had a lower FFM both expressed in kilograms and after correction for height squared. The prevalence of sarcopenia was higher for COPD subjects (38% vs 31%). REE, both in absolute values and adjusted for FFM was significantly higher in COPD patients. Hypermetabolism was found in 60% of COPD cases and 13.7% (P<0.01) of healthy subjects. No relationship was found in COPD patients between the measured/predicted REE ratio (REE(m)/REE(p)) and FEV1. In the hypermetabolic COPD subgroup, the REE(m)/REE(p) ratio correlated with 6MWT. CONCLUSIONS: Elderly patients with stable COPD develop an increased REE. This hypermetabolism seems to be independent of the severity of the pulmonary obstruction and to influence the patient's physical performance. SN - 0954-6111 UR - https://www.unboundmedicine.com/medline/citation/16635565/Body_composition_and_resting_energy_expenditure_in_elderly_male_patients_with_chronic_obstructive_pulmonary_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0954-6111(06)00123-5 DB - PRIME DP - Unbound Medicine ER -