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Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex.
Neurology. 2006 Apr 25; 66(8):1270-2.Neur

Abstract

The authors assessed whether magnetoencephalography/magnetic source imaging (MEG/MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56% sensitivity, 80% specificity, and 77% accuracy (p = 0.02), whereas interictal MEG/MSI fared better (100%, 94%, and 95%, respectively; p < 0.0001). Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.

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Authors+Show Affiliations

Wu JY
Division of Pediatric Neurology, The Brain Research Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. joycewu@mednet.ucla.edu
Sutherling WW
No affiliation info available
Koh S
No affiliation info available
Salamon N
No affiliation info available
Jonas R
No affiliation info available
Yudovin S
No affiliation info available
Sankar R
No affiliation info available
Shields WD
No affiliation info available
Mathern GW
No affiliation info available

MeSH

ChildChild, PreschoolElectroencephalographyEpilepsyFluorodeoxyglucose F18Follow-Up StudiesHumansInfantMagnetic Resonance ImagingMagnetoencephalographyPositron-Emission TomographySensitivity and SpecificityTuberous SclerosisVideotape Recording

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

16636252

Citation

Wu, J Y., et al. "Magnetic Source Imaging Localizes Epileptogenic Zone in Children With Tuberous Sclerosis Complex." Neurology, vol. 66, no. 8, 2006, pp. 1270-2.
Wu JY, Sutherling WW, Koh S, et al. Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex. Neurology. 2006;66(8):1270-2.
Wu, J. Y., Sutherling, W. W., Koh, S., Salamon, N., Jonas, R., Yudovin, S., Sankar, R., Shields, W. D., & Mathern, G. W. (2006). Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex. Neurology, 66(8), 1270-2.
Wu JY, et al. Magnetic Source Imaging Localizes Epileptogenic Zone in Children With Tuberous Sclerosis Complex. Neurology. 2006 Apr 25;66(8):1270-2. PubMed PMID: 16636252.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex. AU - Wu,J Y, AU - Sutherling,W W, AU - Koh,S, AU - Salamon,N, AU - Jonas,R, AU - Yudovin,S, AU - Sankar,R, AU - Shields,W D, AU - Mathern,G W, PY - 2006/4/26/pubmed PY - 2006/6/6/medline PY - 2006/4/26/entrez SP - 1270 EP - 2 JF - Neurology JO - Neurology VL - 66 IS - 8 N2 - The authors assessed whether magnetoencephalography/magnetic source imaging (MEG/MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56% sensitivity, 80% specificity, and 77% accuracy (p = 0.02), whereas interictal MEG/MSI fared better (100%, 94%, and 95%, respectively; p < 0.0001). Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy. SN - 1526-632X UR - https://www.unboundmedicine.com/medline/citation/16636252/Magnetic_source_imaging_localizes_epileptogenic_zone_in_children_with_tuberous_sclerosis_complex_ L2 - http://www.neurology.org/cgi/pmidlookup?view=long&amp;pmid=16636252 DB - PRIME DP - Unbound Medicine ER -