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Bisabolane sesquiterpenes from the roots of Ligularia cymbulifera.
J Nat Prod. 2006 Apr; 69(4):695-9.JN

Abstract

Eight new highly oxygenated bisabolane sesquiterpenes (1-8), of which one contains a chlorine atom, were obtained in a phytochemical investigation of the roots of Ligularia cymbulifera, and their structures were elucidated by interpretation of spectroscopic data. Their relative configurations were clarified by a detailed analysis of (1)H NMR coupling constants and by NOE experiments. Compounds 1-8 were evaluated for antimicrobial activity against three bacterial cultures and a yeast culture.

Authors+Show Affiliations

Liu CM
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People's Republic of China.
Fei DQ
No affiliation info available
Wu QH
No affiliation info available
Gao K
No affiliation info available

MeSH

Anti-Infective AgentsAsteraceaeCandida albicansEscherichia coliMethicillin ResistanceMicrobial Sensitivity TestsMolecular StructurePlant RootsPlants, MedicinalSesquiterpenesStaphylococcus aureus

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16643057

Citation

Liu, Chun-Mei, et al. "Bisabolane Sesquiterpenes From the Roots of Ligularia Cymbulifera." Journal of Natural Products, vol. 69, no. 4, 2006, pp. 695-9.
Liu CM, Fei DQ, Wu QH, et al. Bisabolane sesquiterpenes from the roots of Ligularia cymbulifera. J Nat Prod. 2006;69(4):695-9.
Liu, C. M., Fei, D. Q., Wu, Q. H., & Gao, K. (2006). Bisabolane sesquiterpenes from the roots of Ligularia cymbulifera. Journal of Natural Products, 69(4), 695-9.
Liu CM, et al. Bisabolane Sesquiterpenes From the Roots of Ligularia Cymbulifera. J Nat Prod. 2006;69(4):695-9. PubMed PMID: 16643057.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bisabolane sesquiterpenes from the roots of Ligularia cymbulifera. AU - Liu,Chun-Mei, AU - Fei,Dong-Qing, AU - Wu,Qiu-Hong, AU - Gao,Kun, PY - 2006/4/29/pubmed PY - 2006/6/22/medline PY - 2006/4/29/entrez SP - 695 EP - 9 JF - Journal of natural products JO - J Nat Prod VL - 69 IS - 4 N2 - Eight new highly oxygenated bisabolane sesquiterpenes (1-8), of which one contains a chlorine atom, were obtained in a phytochemical investigation of the roots of Ligularia cymbulifera, and their structures were elucidated by interpretation of spectroscopic data. Their relative configurations were clarified by a detailed analysis of (1)H NMR coupling constants and by NOE experiments. Compounds 1-8 were evaluated for antimicrobial activity against three bacterial cultures and a yeast culture. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/16643057/Bisabolane_sesquiterpenes_from_the_roots_of_Ligularia_cymbulifera_ DB - PRIME DP - Unbound Medicine ER -