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Neurobehavioral function in children with low blood lead concentrations.
Neurotoxicology. 2007 Mar; 28(2):421-5.N

Abstract

Debate continues as to whether low blood lead level, even below 5 microg/dl, impairs neurodevelopmental function in children. This study assessed the association between neurodevelopmental performance and lead exposure below 5 microg/dl in Korean children. Data were collected from 61 children, aged 7-16 years with a mean blood lead level of 2.9 microg/dl, who participated with their mothers. Neurodevelopmental function was measured with computer-based neurobehavioral tests. The analyzed data included children's performances on five neurobehavioral tests as the dependent variables, and children's blood lead level, sex, age, and mother's performance as the four independent variables. For simple reaction time and digit span, which, respectively reflect attention and short-term memory, there was a small and significant association between the children's neurodevelopmental performance and their blood lead levels (p=0.05, 0.08, respectively). Our study suggests that low blood lead below 5 microg/dl can influence children's neurobehavioral performance.

Authors+Show Affiliations

School of Public Health and Institute of Health and Environment, Seoul National University, Chongno-gu Yongeun-dong 28, Seoul 110-460, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16644013

Citation

Min, Jin-Young, et al. "Neurobehavioral Function in Children With Low Blood Lead Concentrations." Neurotoxicology, vol. 28, no. 2, 2007, pp. 421-5.
Min JY, Min KB, Cho SI, et al. Neurobehavioral function in children with low blood lead concentrations. Neurotoxicology. 2007;28(2):421-5.
Min, J. Y., Min, K. B., Cho, S. I., Kim, R., Sakong, J., & Paek, D. (2007). Neurobehavioral function in children with low blood lead concentrations. Neurotoxicology, 28(2), 421-5.
Min JY, et al. Neurobehavioral Function in Children With Low Blood Lead Concentrations. Neurotoxicology. 2007;28(2):421-5. PubMed PMID: 16644013.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neurobehavioral function in children with low blood lead concentrations. AU - Min,Jin-Young, AU - Min,Kyoung-Bok, AU - Cho,Sung-Il, AU - Kim,Rokho, AU - Sakong,Joon, AU - Paek,Domyung, Y1 - 2006/03/24/ PY - 2005/10/20/received PY - 2006/03/10/accepted PY - 2006/4/29/pubmed PY - 2007/8/22/medline PY - 2006/4/29/entrez SP - 421 EP - 5 JF - Neurotoxicology JO - Neurotoxicology VL - 28 IS - 2 N2 - Debate continues as to whether low blood lead level, even below 5 microg/dl, impairs neurodevelopmental function in children. This study assessed the association between neurodevelopmental performance and lead exposure below 5 microg/dl in Korean children. Data were collected from 61 children, aged 7-16 years with a mean blood lead level of 2.9 microg/dl, who participated with their mothers. Neurodevelopmental function was measured with computer-based neurobehavioral tests. The analyzed data included children's performances on five neurobehavioral tests as the dependent variables, and children's blood lead level, sex, age, and mother's performance as the four independent variables. For simple reaction time and digit span, which, respectively reflect attention and short-term memory, there was a small and significant association between the children's neurodevelopmental performance and their blood lead levels (p=0.05, 0.08, respectively). Our study suggests that low blood lead below 5 microg/dl can influence children's neurobehavioral performance. SN - 0161-813X UR - https://www.unboundmedicine.com/medline/citation/16644013/Neurobehavioral_function_in_children_with_low_blood_lead_concentrations_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-813X(06)00087-8 DB - PRIME DP - Unbound Medicine ER -