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A case of pulmonary cryptococcosis by capsule-deficient Cryptococcus neoformans.
Korean J Intern Med. 2006 Mar; 21(1):83-7.KJ

Abstract

Pulmonary infection by capsule-deficient Cryptococcus neoformans (CDCN) is a very rare form of pneumonia and it is seldom seen in the immunocompetent host. The authors experienced a case of pulmonary cryptococcosis by CDCN in 25-year-old woman who was without any significant underlying disease. The diagnosis was made from the percutaneous lung biopsy and special tissue staining, including Fontana-Masson silver (FMS) staining. Fungal culture confirmed the diagnosis afterward. Her clinical and radiologic features improved under treatment with fluconazol. It's known that CDCN is not so readily confirmed because fungal culture does not always result in growth of the organism and the empirical fungal stain is not helpful for the differentiation between CDCN and the other infections that are caused by the nonencapsulated yeast-like organisms. In this report, we emphasize the diagnostic value of performing FMS staining for differentiating a CDCN infection from the other confusing nonencapsulated yeast-like organisms.

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Authors+Show Affiliations

Cheon WS
Division of Pulmonology, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea.
Eom KS
No affiliation info available
Yoo BK
No affiliation info available
Jang SH
No affiliation info available
Bahn JW
No affiliation info available
Kim DG
No affiliation info available
Jung KS
No affiliation info available

MeSH

AdultChest PainCoughCryptococcosisCryptococcus neoformansFemaleHumansLung DiseasesSilver Nitrate

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16646572

Citation

Cheon, Won Seok, et al. "A Case of Pulmonary Cryptococcosis By Capsule-deficient Cryptococcus Neoformans." The Korean Journal of Internal Medicine, vol. 21, no. 1, 2006, pp. 83-7.
Cheon WS, Eom KS, Yoo BK, et al. A case of pulmonary cryptococcosis by capsule-deficient Cryptococcus neoformans. Korean J Intern Med. 2006;21(1):83-7.
Cheon, W. S., Eom, K. S., Yoo, B. K., Jang, S. H., Bahn, J. W., Kim, D. G., & Jung, K. S. (2006). A case of pulmonary cryptococcosis by capsule-deficient Cryptococcus neoformans. The Korean Journal of Internal Medicine, 21(1), 83-7.
Cheon WS, et al. A Case of Pulmonary Cryptococcosis By Capsule-deficient Cryptococcus Neoformans. Korean J Intern Med. 2006;21(1):83-7. PubMed PMID: 16646572.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A case of pulmonary cryptococcosis by capsule-deficient Cryptococcus neoformans. AU - Cheon,Won Seok, AU - Eom,Kwang-Seok, AU - Yoo,Byoung Kwan, AU - Jang,Seung Hun, AU - Bahn,Joon-Woo, AU - Kim,Dong-Gyu, AU - Jung,Ki-Suck, PY - 2006/5/2/pubmed PY - 2006/6/8/medline PY - 2006/5/2/entrez SP - 83 EP - 7 JF - The Korean journal of internal medicine JO - Korean J Intern Med VL - 21 IS - 1 N2 - Pulmonary infection by capsule-deficient Cryptococcus neoformans (CDCN) is a very rare form of pneumonia and it is seldom seen in the immunocompetent host. The authors experienced a case of pulmonary cryptococcosis by CDCN in 25-year-old woman who was without any significant underlying disease. The diagnosis was made from the percutaneous lung biopsy and special tissue staining, including Fontana-Masson silver (FMS) staining. Fungal culture confirmed the diagnosis afterward. Her clinical and radiologic features improved under treatment with fluconazol. It's known that CDCN is not so readily confirmed because fungal culture does not always result in growth of the organism and the empirical fungal stain is not helpful for the differentiation between CDCN and the other infections that are caused by the nonencapsulated yeast-like organisms. In this report, we emphasize the diagnostic value of performing FMS staining for differentiating a CDCN infection from the other confusing nonencapsulated yeast-like organisms. SN - 1226-3303 UR - https://www.unboundmedicine.com/medline/citation/16646572/A_case_of_pulmonary_cryptococcosis_by_capsule_deficient_Cryptococcus_neoformans_ DB - PRIME DP - Unbound Medicine ER -