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Clinical outcomes of EMR for gastric tumors: historical pilot evaluation between endoscopic submucosal dissection and conventional mucosal resection.
Gastrointest Endosc 2006; 63(6):776-82GE

Abstract

BACKGROUND

EMR is currently a standard treatment for mucosal gastric tumors. Endoscopic submucosal dissection (ESD) has been developed for en bloc resection.

OBJECTIVE

We evaluated the clinical outcomes of ESD compared with conventional EMR.

DESIGN

Not applicable.

SETTING

A historical control study was performed between EMR and ESD.

PATIENTS

EMR of 245 gastric tumors was performed in 229 patients. Lesions were divided into two groups. Conventional EMR was performed in group A from February 1999 to June 2001, and ESD was performed in group B from July 2001 to March 2004. Group B was divided into subgroups: subgroup B-1 underwent ESD from July 2001 to March 2003 and subgroup B-2 from April 2003 to March 2004.

INTERVENTIONS

All lesions were resected with conventional EMR or with ESD.

MAIN OUTCOME MEASUREMENTS

En bloc resection rate, rate in completeness of resection, required time, remnant ratio, and complications were evaluated.

RESULTS

With regard to lesions >10 mm in size, the en bloc resection rate and the rate in completeness of resection of group B was significantly higher than that of group A (p < 0.01). Although the required time was longer in group B than A (p < 0.01), it was shorter in subgroup B-2 compared with B-1 (p < 0.05) with lesions < or =10 mm in size. The remnant ratio and perforation rate were not different between groups.

LIMITATIONS

Not applicable.

CONCLUSIONS

The en bloc resection rate was better with ESD than with conventional EMR. The required time was longer in ESD, but this disadvantage might be improved with experience.

Authors+Show Affiliations

Department of Internal Medicine, Radiology, Pathology, Saga Prefectural Hospital Koseikan, Saga Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16650537

Citation

Watanabe, Kenichiro, et al. "Clinical Outcomes of EMR for Gastric Tumors: Historical Pilot Evaluation Between Endoscopic Submucosal Dissection and Conventional Mucosal Resection." Gastrointestinal Endoscopy, vol. 63, no. 6, 2006, pp. 776-82.
Watanabe K, Ogata S, Kawazoe S, et al. Clinical outcomes of EMR for gastric tumors: historical pilot evaluation between endoscopic submucosal dissection and conventional mucosal resection. Gastrointest Endosc. 2006;63(6):776-82.
Watanabe, K., Ogata, S., Kawazoe, S., Watanabe, K., Koyama, T., Kajiwara, T., ... Fujimoto, K. (2006). Clinical outcomes of EMR for gastric tumors: historical pilot evaluation between endoscopic submucosal dissection and conventional mucosal resection. Gastrointestinal Endoscopy, 63(6), pp. 776-82.
Watanabe K, et al. Clinical Outcomes of EMR for Gastric Tumors: Historical Pilot Evaluation Between Endoscopic Submucosal Dissection and Conventional Mucosal Resection. Gastrointest Endosc. 2006;63(6):776-82. PubMed PMID: 16650537.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical outcomes of EMR for gastric tumors: historical pilot evaluation between endoscopic submucosal dissection and conventional mucosal resection. AU - Watanabe,Kenichiro, AU - Ogata,Shinichi, AU - Kawazoe,Seiji, AU - Watanabe,Kazuyo, AU - Koyama,Takanori, AU - Kajiwara,Tetsuro, AU - Shimoda,Yuichiro, AU - Takase,Yukari, AU - Irie,Kouji, AU - Mizuguchi,Masanobu, AU - Tsunada,Seiji, AU - Iwakiri,Ryuichi, AU - Fujimoto,Kazuma, PY - 2005/02/13/received PY - 2005/08/31/accepted PY - 2006/5/3/pubmed PY - 2006/10/18/medline PY - 2006/5/3/entrez SP - 776 EP - 82 JF - Gastrointestinal endoscopy JO - Gastrointest. Endosc. VL - 63 IS - 6 N2 - BACKGROUND: EMR is currently a standard treatment for mucosal gastric tumors. Endoscopic submucosal dissection (ESD) has been developed for en bloc resection. OBJECTIVE: We evaluated the clinical outcomes of ESD compared with conventional EMR. DESIGN: Not applicable. SETTING: A historical control study was performed between EMR and ESD. PATIENTS: EMR of 245 gastric tumors was performed in 229 patients. Lesions were divided into two groups. Conventional EMR was performed in group A from February 1999 to June 2001, and ESD was performed in group B from July 2001 to March 2004. Group B was divided into subgroups: subgroup B-1 underwent ESD from July 2001 to March 2003 and subgroup B-2 from April 2003 to March 2004. INTERVENTIONS: All lesions were resected with conventional EMR or with ESD. MAIN OUTCOME MEASUREMENTS: En bloc resection rate, rate in completeness of resection, required time, remnant ratio, and complications were evaluated. RESULTS: With regard to lesions >10 mm in size, the en bloc resection rate and the rate in completeness of resection of group B was significantly higher than that of group A (p < 0.01). Although the required time was longer in group B than A (p < 0.01), it was shorter in subgroup B-2 compared with B-1 (p < 0.05) with lesions < or =10 mm in size. The remnant ratio and perforation rate were not different between groups. LIMITATIONS: Not applicable. CONCLUSIONS: The en bloc resection rate was better with ESD than with conventional EMR. The required time was longer in ESD, but this disadvantage might be improved with experience. SN - 0016-5107 UR - https://www.unboundmedicine.com/medline/citation/16650537/Clinical_outcomes_of_EMR_for_gastric_tumors:_historical_pilot_evaluation_between_endoscopic_submucosal_dissection_and_conventional_mucosal_resection_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0016-5107(05)02758-6 DB - PRIME DP - Unbound Medicine ER -