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Enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by bifunctional tridentate bis(oxazoline)-Zn(II) complex.
Org Lett. 2006 May 11; 8(10):2115-8.OL

Abstract

[reaction: see text] A more practical and efficient catalytic asymmetric Friedel-Crafts alkylation of indoles with nitroalkenes using bifunctional tridentate bis(oxazoline)-Zn(OTf)(2) as catalyst has been developed. Various types of the nitroalkylated indoles were obtained in excellent yields (85-99%) and high enantioselectivities (up to 98% ee).

Authors+Show Affiliations

Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, PR China.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16671795

Citation

Lu, Shao-Feng, et al. "Enantioselective Friedel-Crafts Alkylation of Indoles With Nitroalkenes Catalyzed By Bifunctional Tridentate bis(oxazoline)-Zn(II) Complex." Organic Letters, vol. 8, no. 10, 2006, pp. 2115-8.
Lu SF, Du DM, Xu J. Enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by bifunctional tridentate bis(oxazoline)-Zn(II) complex. Org Lett. 2006;8(10):2115-8.
Lu, S. F., Du, D. M., & Xu, J. (2006). Enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by bifunctional tridentate bis(oxazoline)-Zn(II) complex. Organic Letters, 8(10), 2115-8.
Lu SF, Du DM, Xu J. Enantioselective Friedel-Crafts Alkylation of Indoles With Nitroalkenes Catalyzed By Bifunctional Tridentate bis(oxazoline)-Zn(II) Complex. Org Lett. 2006 May 11;8(10):2115-8. PubMed PMID: 16671795.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by bifunctional tridentate bis(oxazoline)-Zn(II) complex. AU - Lu,Shao-Feng, AU - Du,Da-Ming, AU - Xu,Jiaxi, PY - 2006/5/5/pubmed PY - 2006/5/5/medline PY - 2006/5/5/entrez SP - 2115 EP - 8 JF - Organic letters JO - Org Lett VL - 8 IS - 10 N2 - [reaction: see text] A more practical and efficient catalytic asymmetric Friedel-Crafts alkylation of indoles with nitroalkenes using bifunctional tridentate bis(oxazoline)-Zn(OTf)(2) as catalyst has been developed. Various types of the nitroalkylated indoles were obtained in excellent yields (85-99%) and high enantioselectivities (up to 98% ee). SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/16671795/Enantioselective_Friedel_Crafts_alkylation_of_indoles_with_nitroalkenes_catalyzed_by_bifunctional_tridentate_bis_oxazoline__Zn_II__complex_ DB - PRIME DP - Unbound Medicine ER -
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