Tags

Type your tag names separated by a space and hit enter

Event driven electrical stimulation of the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in multiple sclerosis.
Neurourol Urodyn. 2006; 25(4):349-55.NU

Abstract

AIMS

The aim of this study was to evaluate the effect of automatic event driven electrical stimulation on the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in patients suffering from Multiple Sclerosis.

METHODS

A total of 10 patients participated in the study. Detrusor pressure was recorded during physiological filling of the bladder and electrical stimulation was applied with surface electrodes whenever the detrusor pressure exceeded 10 cm H(2)O.

RESULTS

In seven of the eight patients, where neurogenic detrusor overactivity was observed an average of 12 detrusor contractions could be inhibited by stimulation. In one patient, however, stimulation failed to inhibit the detrusor contractions. The average increase in bladder volume from first suppressed detrusor contraction until leakage was 94% (range: 22-366%). On average, the time from first suppressed contraction until leakage was 15 min and 50 sec (range: 4 min 58 sec-32 min 5 sec) with an average physiological filling rate of 8 ml/min. Urgency was effectively suppressed at the onset of stimulation.

CONCLUSIONS

The results indicate that involuntary detrusor contractions in patients with multiple sclerosis can effectively be inhibited with event driven stimulation, hereby improving bladder capacity and reducing the number of incontinence episodes. However, the used method for detecting detrusor contractions is not suitable in a chronic setting and alternative techniques needs to be investigated if stimulation should be applied automatically.

Authors+Show Affiliations

Center for Sensory-Motor Interaction, Department of Health Science and Technology, Aalborg University, Aalborg Oest, Denmark. mvf@smi.auc.dkNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16673380

Citation

Fjorback, Morten Voss, et al. "Event Driven Electrical Stimulation of the Dorsal Penile/clitoral Nerve for Management of Neurogenic Detrusor Overactivity in Multiple Sclerosis." Neurourology and Urodynamics, vol. 25, no. 4, 2006, pp. 349-55.
Fjorback MV, Rijkhoff N, Petersen T, et al. Event driven electrical stimulation of the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in multiple sclerosis. Neurourol Urodyn. 2006;25(4):349-55.
Fjorback, M. V., Rijkhoff, N., Petersen, T., Nohr, M., & Sinkjaer, T. (2006). Event driven electrical stimulation of the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in multiple sclerosis. Neurourology and Urodynamics, 25(4), 349-55.
Fjorback MV, et al. Event Driven Electrical Stimulation of the Dorsal Penile/clitoral Nerve for Management of Neurogenic Detrusor Overactivity in Multiple Sclerosis. Neurourol Urodyn. 2006;25(4):349-55. PubMed PMID: 16673380.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Event driven electrical stimulation of the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in multiple sclerosis. AU - Fjorback,Morten Voss, AU - Rijkhoff,Nico, AU - Petersen,Thor, AU - Nohr,Mads, AU - Sinkjaer,Thomas, PY - 2006/5/5/pubmed PY - 2006/10/13/medline PY - 2006/5/5/entrez SP - 349 EP - 55 JF - Neurourology and urodynamics JO - Neurourol Urodyn VL - 25 IS - 4 N2 - AIMS: The aim of this study was to evaluate the effect of automatic event driven electrical stimulation on the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in patients suffering from Multiple Sclerosis. METHODS: A total of 10 patients participated in the study. Detrusor pressure was recorded during physiological filling of the bladder and electrical stimulation was applied with surface electrodes whenever the detrusor pressure exceeded 10 cm H(2)O. RESULTS: In seven of the eight patients, where neurogenic detrusor overactivity was observed an average of 12 detrusor contractions could be inhibited by stimulation. In one patient, however, stimulation failed to inhibit the detrusor contractions. The average increase in bladder volume from first suppressed detrusor contraction until leakage was 94% (range: 22-366%). On average, the time from first suppressed contraction until leakage was 15 min and 50 sec (range: 4 min 58 sec-32 min 5 sec) with an average physiological filling rate of 8 ml/min. Urgency was effectively suppressed at the onset of stimulation. CONCLUSIONS: The results indicate that involuntary detrusor contractions in patients with multiple sclerosis can effectively be inhibited with event driven stimulation, hereby improving bladder capacity and reducing the number of incontinence episodes. However, the used method for detecting detrusor contractions is not suitable in a chronic setting and alternative techniques needs to be investigated if stimulation should be applied automatically. SN - 0733-2467 UR - https://www.unboundmedicine.com/medline/citation/16673380/Event_driven_electrical_stimulation_of_the_dorsal_penile/clitoral_nerve_for_management_of_neurogenic_detrusor_overactivity_in_multiple_sclerosis_ L2 - https://doi.org/10.1002/nau.20170 DB - PRIME DP - Unbound Medicine ER -