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Comparison of operative and functional outcomes of laparoscopic radical prostatectomy and radical retropubic prostatectomy: single surgeon experience.
Urology. 2006 Jun; 67(6):1241-6.U

Abstract

OBJECTIVES

To compare radical retropubic prostatectomy (RRP) and laparoscopic radical prostatectomy (LRP) outcomes in a contemporary series.

METHODS

A total of 70 LRP patients operated on between 2001 and 2002 with at least 18 months of follow-up were selected. These patients were compared with a matched cohort of 70 patients who had undergone RRP by the same surgeon from 1999 to 2001. The baseline patient characteristics, perioperative and histologic parameters, recovery time, complications, and 18-month functional data were compared.

RESULTS

No significant differences were found in the preoperative characteristics. The mean operative time was 181.8 +/- 18.7 minutes for RRP and 246.4 +/- 46.1 minutes for LRP (P <0.0001). The mean estimated blood loss was 563.2 mL for RRP and 275.8 mL for LRP (P <0.0001). The positive margin rate was 20% and 15.7% for the RRP and LRP groups, respectively (P = NS). The mean pain score on postoperative day 1 was 4.5 in the LRP group and 7.8 in the RRP group on an analog pain score of 0 to 10 (P = 0.02). Full recovery was achieved at 33 +/- 17 days and 45 +/- 20 days for the LRP and RRP groups, respectively (P <0.001). The total perioperative complication rate for LRP and RRP was comparable at 18.5% and 15.7%, respectively. The diurnal continence rate (no pads) for the LRP and RRP groups was 70%, 90%, and 92.8% and 71.4%, 87.6%, and 92% at 6, 12, and 18 months, respectively (P = NS). The potency rate after bilateral neurovascular preservation with or without sildenafil for the LRP and RRP group was 55%, 72.6%, and 79.5% and 43%, 58%, and 72.4% at 6, 12, and 18 months, respectively (P = NS).

CONCLUSIONS

LRP is well tolerated and provides short-term oncologic and functional results comparable to those of RRP.

Authors+Show Affiliations

Department of Urology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA. rghavami@montefiore.orgNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16678887

Citation

Ghavamian, Reza, et al. "Comparison of Operative and Functional Outcomes of Laparoscopic Radical Prostatectomy and Radical Retropubic Prostatectomy: Single Surgeon Experience." Urology, vol. 67, no. 6, 2006, pp. 1241-6.
Ghavamian R, Knoll A, Boczko J, et al. Comparison of operative and functional outcomes of laparoscopic radical prostatectomy and radical retropubic prostatectomy: single surgeon experience. Urology. 2006;67(6):1241-6.
Ghavamian, R., Knoll, A., Boczko, J., & Melman, A. (2006). Comparison of operative and functional outcomes of laparoscopic radical prostatectomy and radical retropubic prostatectomy: single surgeon experience. Urology, 67(6), 1241-6.
Ghavamian R, et al. Comparison of Operative and Functional Outcomes of Laparoscopic Radical Prostatectomy and Radical Retropubic Prostatectomy: Single Surgeon Experience. Urology. 2006;67(6):1241-6. PubMed PMID: 16678887.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of operative and functional outcomes of laparoscopic radical prostatectomy and radical retropubic prostatectomy: single surgeon experience. AU - Ghavamian,Reza, AU - Knoll,Abraham, AU - Boczko,Judd, AU - Melman,Arnold, Y1 - 2006/05/06/ PY - 2005/09/16/received PY - 2005/11/07/revised PY - 2005/12/07/accepted PY - 2006/5/9/pubmed PY - 2006/7/14/medline PY - 2006/5/9/entrez SP - 1241 EP - 6 JF - Urology JO - Urology VL - 67 IS - 6 N2 - OBJECTIVES: To compare radical retropubic prostatectomy (RRP) and laparoscopic radical prostatectomy (LRP) outcomes in a contemporary series. METHODS: A total of 70 LRP patients operated on between 2001 and 2002 with at least 18 months of follow-up were selected. These patients were compared with a matched cohort of 70 patients who had undergone RRP by the same surgeon from 1999 to 2001. The baseline patient characteristics, perioperative and histologic parameters, recovery time, complications, and 18-month functional data were compared. RESULTS: No significant differences were found in the preoperative characteristics. The mean operative time was 181.8 +/- 18.7 minutes for RRP and 246.4 +/- 46.1 minutes for LRP (P <0.0001). The mean estimated blood loss was 563.2 mL for RRP and 275.8 mL for LRP (P <0.0001). The positive margin rate was 20% and 15.7% for the RRP and LRP groups, respectively (P = NS). The mean pain score on postoperative day 1 was 4.5 in the LRP group and 7.8 in the RRP group on an analog pain score of 0 to 10 (P = 0.02). Full recovery was achieved at 33 +/- 17 days and 45 +/- 20 days for the LRP and RRP groups, respectively (P <0.001). The total perioperative complication rate for LRP and RRP was comparable at 18.5% and 15.7%, respectively. The diurnal continence rate (no pads) for the LRP and RRP groups was 70%, 90%, and 92.8% and 71.4%, 87.6%, and 92% at 6, 12, and 18 months, respectively (P = NS). The potency rate after bilateral neurovascular preservation with or without sildenafil for the LRP and RRP group was 55%, 72.6%, and 79.5% and 43%, 58%, and 72.4% at 6, 12, and 18 months, respectively (P = NS). CONCLUSIONS: LRP is well tolerated and provides short-term oncologic and functional results comparable to those of RRP. SN - 1527-9995 UR - https://www.unboundmedicine.com/medline/citation/16678887/Comparison_of_operative_and_functional_outcomes_of_laparoscopic_radical_prostatectomy_and_radical_retropubic_prostatectomy:_single_surgeon_experience_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0090-4295(05)01771-1 DB - PRIME DP - Unbound Medicine ER -