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A 308-nm monochromatic excimer light in the treatment of palmoplantar psoriasis.

Abstract

BACKGROUND

Various reports have shown the efficacy of narrow-band UVB (311-313 nm) and excimer laser (308 nm) in the treatment of psoriasis.

OBJECTIVE

To prove the efficacy of light produced by xenon-chloride excimer at 308 nm (monochromatic excimer light, MEL) in the treatment of palmoplantar psoriasis (PP).

METHODS

Fifty-four patients (29 male and 25 female) affected by PP were treated with MEL every 7-14 days. A mean number of 10 sessions was performed with an increase of the dose depending on patient's skin type and response.

RESULTS

All 54 patients completed the treatment. After 4 months of MEL we observed a complete remission in 31 patients, a partial remission in 13 patients, and a moderate improvement in 10 patients.

CONCLUSIONS

These results suggest that MEL can be considered as a valid therapeutic option for treatment of selected forms of PP.

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  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Dermatology, University of Rome, Tor Vergata, Italy.

    , ,

    Source

    MeSH

    Dose-Response Relationship, Radiation
    Female
    Foot Dermatoses
    Hand Dermatoses
    Humans
    Male
    Middle Aged
    Psoriasis
    Treatment Outcome
    Ultraviolet Therapy

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    16684278

    Citation

    Nisticò, S P., et al. "A 308-nm Monochromatic Excimer Light in the Treatment of Palmoplantar Psoriasis." Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 20, no. 5, 2006, pp. 523-6.
    Nisticò SP, Saraceno R, Stefanescu S, et al. A 308-nm monochromatic excimer light in the treatment of palmoplantar psoriasis. J Eur Acad Dermatol Venereol. 2006;20(5):523-6.
    Nisticò, S. P., Saraceno, R., Stefanescu, S., & Chimenti, S. (2006). A 308-nm monochromatic excimer light in the treatment of palmoplantar psoriasis. Journal of the European Academy of Dermatology and Venereology : JEADV, 20(5), pp. 523-6.
    Nisticò SP, et al. A 308-nm Monochromatic Excimer Light in the Treatment of Palmoplantar Psoriasis. J Eur Acad Dermatol Venereol. 2006;20(5):523-6. PubMed PMID: 16684278.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - A 308-nm monochromatic excimer light in the treatment of palmoplantar psoriasis. AU - Nisticò,S P, AU - Saraceno,R, AU - Stefanescu,S, AU - Chimenti,S, PY - 2006/5/11/pubmed PY - 2006/10/27/medline PY - 2006/5/11/entrez SP - 523 EP - 6 JF - Journal of the European Academy of Dermatology and Venereology : JEADV JO - J Eur Acad Dermatol Venereol VL - 20 IS - 5 N2 - BACKGROUND: Various reports have shown the efficacy of narrow-band UVB (311-313 nm) and excimer laser (308 nm) in the treatment of psoriasis. OBJECTIVE: To prove the efficacy of light produced by xenon-chloride excimer at 308 nm (monochromatic excimer light, MEL) in the treatment of palmoplantar psoriasis (PP). METHODS: Fifty-four patients (29 male and 25 female) affected by PP were treated with MEL every 7-14 days. A mean number of 10 sessions was performed with an increase of the dose depending on patient's skin type and response. RESULTS: All 54 patients completed the treatment. After 4 months of MEL we observed a complete remission in 31 patients, a partial remission in 13 patients, and a moderate improvement in 10 patients. CONCLUSIONS: These results suggest that MEL can be considered as a valid therapeutic option for treatment of selected forms of PP. SN - 0926-9959 UR - https://www.unboundmedicine.com/medline/citation/16684278/A_308_nm_monochromatic_excimer_light_in_the_treatment_of_palmoplantar_psoriasis_ L2 - https://doi.org/10.1111/j.1468-3083.2006.01503.x DB - PRIME DP - Unbound Medicine ER -