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[Polycystic ovary syndrome as expression of 3-beta-hydroxysteroid dehydrogenase deficiency].
Rev Chil Obstet Ginecol. 1991; 56(3):213-6.RC

Abstract

Late-onset adrenal enzymatic deficiencies are a common cause of hirsutism. They can produce a PCO syndrome-like clinical course, underscoring the multi-causality of this condition. We report a 18 year old woman with secondary amenorrhea and hirsutism, whose serum levels of testosterone and DHEA-S were 175 ng/dl and 7.3 micrograms/ml and the LH/FSH ratio was 5.9. Dexamethasone decreased testosterone and DHEA-S levels, while the ACTH stimulation test increased the 17 hydroxypregnenolone serum concentration and the 17 hydroxypregnenolone/17 hydroxyprogesterone ratio to values considered diagnostic of 3 beta hydroxysteroid dehydrogenase deficiency.

Authors+Show Affiliations

Departamento de Endocrinología, Metabolismo y Nutrición, Hospital Clínico, Universidad Católica de Chile.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

spa

PubMed ID

1668983

Citation

Sapunar, J, et al. "[Polycystic Ovary Syndrome as Expression of 3-beta-hydroxysteroid Dehydrogenase Deficiency]." Revista Chilena De Obstetricia Y Ginecologia, vol. 56, no. 3, 1991, pp. 213-6.
Sapunar J, Triantafilo Y, Arteaga E, et al. [Polycystic ovary syndrome as expression of 3-beta-hydroxysteroid dehydrogenase deficiency]. Rev Chil Obstet Ginecol. 1991;56(3):213-6.
Sapunar, J., Triantafilo, Y., Arteaga, E., Rojas, A., Campino, C., López, J. M., & Rodríguez, J. A. (1991). [Polycystic ovary syndrome as expression of 3-beta-hydroxysteroid dehydrogenase deficiency]. Revista Chilena De Obstetricia Y Ginecologia, 56(3), 213-6.
Sapunar J, et al. [Polycystic Ovary Syndrome as Expression of 3-beta-hydroxysteroid Dehydrogenase Deficiency]. Rev Chil Obstet Ginecol. 1991;56(3):213-6. PubMed PMID: 1668983.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Polycystic ovary syndrome as expression of 3-beta-hydroxysteroid dehydrogenase deficiency]. AU - Sapunar,J, AU - Triantafilo,Y, AU - Arteaga,E, AU - Rojas,A, AU - Campino,C, AU - López,J M, AU - Rodríguez,J A, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 213 EP - 6 JF - Revista chilena de obstetricia y ginecologia JO - Rev Chil Obstet Ginecol VL - 56 IS - 3 N2 - Late-onset adrenal enzymatic deficiencies are a common cause of hirsutism. They can produce a PCO syndrome-like clinical course, underscoring the multi-causality of this condition. We report a 18 year old woman with secondary amenorrhea and hirsutism, whose serum levels of testosterone and DHEA-S were 175 ng/dl and 7.3 micrograms/ml and the LH/FSH ratio was 5.9. Dexamethasone decreased testosterone and DHEA-S levels, while the ACTH stimulation test increased the 17 hydroxypregnenolone serum concentration and the 17 hydroxypregnenolone/17 hydroxyprogesterone ratio to values considered diagnostic of 3 beta hydroxysteroid dehydrogenase deficiency. SN - 0048-766X UR - https://www.unboundmedicine.com/medline/citation/1668983/[Polycystic_ovary_syndrome_as_expression_of_3_beta_hydroxysteroid_dehydrogenase_deficiency]_ L2 - https://www.diseaseinfosearch.org/result/30 DB - PRIME DP - Unbound Medicine ER -