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The effect of green tea in oxidative stress.
Clin Nutr 2006; 25(5):790-6CN

Abstract

BACKGROUND & AIMS

Green tea, an infusion prepared with the leaves of Camellia sinensis is particularly rich in flavonoids, which are strong antioxidants. Tea drinking, by providing antioxidants, may become valuable in several oxidative stress conditions. Our aim was to evaluate the effect of green tea drinking on some factors reflecting the development of oxidative stress in plasma and in erythrocytes.

METHODS

The study was performed in 34 Portuguese subjects. We evaluated the total antioxidant status (TAS), the lipid peroxidation products-malonyldialdehyde (MDA) and malonyldialdehyde+4-hydroxy-2(E)-nonenal (MDA+4-HNE)-and the oxidative changes in erythrocyte membrane, namely membrane bound haemoglobin (MBH) and the band 3 profile. Analytical evaluations were performed after 3 weeks drinking 1l of water daily, and after 4 weeks drinking 1l of green tea daily. Tea was prepared daily at the same conditions of temperature, time of infusion and concentration.

RESULTS

After green tea drinking, we found a significant reduction in serum levels of MDA and MDA+4-HNE and in the oxidative stress within the erythrocyte, as suggested by a significantly lower value of MBH and by changes in band 3 profile towards a normal mean profile, namely an increase in the band 3 monomer. A rise in the antioxidant capacity was also observed.

CONCLUSIONS

Our data suggest for green tea drinking a beneficial effect, by reducing the development or the enhancement of oxidative stress and, therefore, protecting the individual for oxidative stress diseases. Moreover, we propose further studies about the value of band 3 profile and of MBH in providing a cumulative measurement of the effect of green tea drinking upon the oxidative stress in cells. Moreover, further studies are also needed, to clarify the effect of green tea consumption, the value of regular green tea consumption and the way it should be prepared to reach a healthy effect.

Authors+Show Affiliations

Faculdade Farmácia, Serviço Bioquímica, Universidade Porto, Portugal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16698148

Citation

Coimbra, Susana, et al. "The Effect of Green Tea in Oxidative Stress." Clinical Nutrition (Edinburgh, Scotland), vol. 25, no. 5, 2006, pp. 790-6.
Coimbra S, Castro E, Rocha-Pereira P, et al. The effect of green tea in oxidative stress. Clin Nutr. 2006;25(5):790-6.
Coimbra, S., Castro, E., Rocha-Pereira, P., Rebelo, I., Rocha, S., & Santos-Silva, A. (2006). The effect of green tea in oxidative stress. Clinical Nutrition (Edinburgh, Scotland), 25(5), pp. 790-6.
Coimbra S, et al. The Effect of Green Tea in Oxidative Stress. Clin Nutr. 2006;25(5):790-6. PubMed PMID: 16698148.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of green tea in oxidative stress. AU - Coimbra,Susana, AU - Castro,Elisabeth, AU - Rocha-Pereira,Petronila, AU - Rebelo,Irene, AU - Rocha,Susana, AU - Santos-Silva,Alice, Y1 - 2006/05/15/ PY - 2005/06/17/received PY - 2005/12/02/revised PY - 2006/01/22/accepted PY - 2006/5/16/pubmed PY - 2007/1/17/medline PY - 2006/5/16/entrez SP - 790 EP - 6 JF - Clinical nutrition (Edinburgh, Scotland) JO - Clin Nutr VL - 25 IS - 5 N2 - BACKGROUND & AIMS: Green tea, an infusion prepared with the leaves of Camellia sinensis is particularly rich in flavonoids, which are strong antioxidants. Tea drinking, by providing antioxidants, may become valuable in several oxidative stress conditions. Our aim was to evaluate the effect of green tea drinking on some factors reflecting the development of oxidative stress in plasma and in erythrocytes. METHODS: The study was performed in 34 Portuguese subjects. We evaluated the total antioxidant status (TAS), the lipid peroxidation products-malonyldialdehyde (MDA) and malonyldialdehyde+4-hydroxy-2(E)-nonenal (MDA+4-HNE)-and the oxidative changes in erythrocyte membrane, namely membrane bound haemoglobin (MBH) and the band 3 profile. Analytical evaluations were performed after 3 weeks drinking 1l of water daily, and after 4 weeks drinking 1l of green tea daily. Tea was prepared daily at the same conditions of temperature, time of infusion and concentration. RESULTS: After green tea drinking, we found a significant reduction in serum levels of MDA and MDA+4-HNE and in the oxidative stress within the erythrocyte, as suggested by a significantly lower value of MBH and by changes in band 3 profile towards a normal mean profile, namely an increase in the band 3 monomer. A rise in the antioxidant capacity was also observed. CONCLUSIONS: Our data suggest for green tea drinking a beneficial effect, by reducing the development or the enhancement of oxidative stress and, therefore, protecting the individual for oxidative stress diseases. Moreover, we propose further studies about the value of band 3 profile and of MBH in providing a cumulative measurement of the effect of green tea drinking upon the oxidative stress in cells. Moreover, further studies are also needed, to clarify the effect of green tea consumption, the value of regular green tea consumption and the way it should be prepared to reach a healthy effect. SN - 0261-5614 UR - https://www.unboundmedicine.com/medline/citation/16698148/The_effect_of_green_tea_in_oxidative_stress_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0261-5614(06)00045-8 DB - PRIME DP - Unbound Medicine ER -