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[Impact of the duration of untreated psychosis among patients with a first episode: a one year follow-up study].
Gac Med Mex. 2006 Mar-Apr; 142(2):113-20.GM

Abstract

BACKGROUND

The delay on the onset of specific treatment has several prognostic implications for psychotic patients. Duration of untreated psychosis (DUP) has been considered a prognostic variable. A longer DUP has been associated with a poor clinical outcome.

OBJECTIVE

To determine the DUP in a sample of first-episode psychotic patients and its relationship with recovery and relapse on a one-year follow-up study.

MATERIAL AND METHODS

A sample of 66 first-episode psychotic patients was recruited and divided according to their diagnoses in affective and non-affective psychoses. Diagnoses were obtained with SCAN and DUP was registered for each patient. A clinical assessment for psychotic and affective symptoms was performed using standardized instruments.

RESULTS

All patient studied showed clinical improvement during follow-up. Patients with a longer DUP showed poorer psychosocial adjustment and lower recovery indexes. Treatment suspension was the main variable associated with relapse.

CONCLUSIONS

DUP is an important prognostic variable. Early detection programs are required to decrease the period between illness onset, diagnosis and treatment in first-episode psychotic patients.

Authors+Show Affiliations

Subdirección de Psiquiatría, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suarez, Mexico DF, México. rogelioapiquian@yahoo.com.mxNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

spa

PubMed ID

16711545

Citation

Apiquián-Guitart, Rogelio, et al. "[Impact of the Duration of Untreated Psychosis Among Patients With a First Episode: a One Year Follow-up Study]." Gaceta Medica De Mexico, vol. 142, no. 2, 2006, pp. 113-20.
Apiquián-Guitart R, Fresán-Orellana A, García-Anaya M, et al. [Impact of the duration of untreated psychosis among patients with a first episode: a one year follow-up study]. Gac Med Mex. 2006;142(2):113-20.
Apiquián-Guitart, R., Fresán-Orellana, A., García-Anaya, M., Lóyzaga-Mendoza, C., & Nicolini-Sánchez, H. (2006). [Impact of the duration of untreated psychosis among patients with a first episode: a one year follow-up study]. Gaceta Medica De Mexico, 142(2), 113-20.
Apiquián-Guitart R, et al. [Impact of the Duration of Untreated Psychosis Among Patients With a First Episode: a One Year Follow-up Study]. Gac Med Mex. 2006 Mar-Apr;142(2):113-20. PubMed PMID: 16711545.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Impact of the duration of untreated psychosis among patients with a first episode: a one year follow-up study]. AU - Apiquián-Guitart,Rogelio, AU - Fresán-Orellana,Ana, AU - García-Anaya,Maria, AU - Lóyzaga-Mendoza,Cristina, AU - Nicolini-Sánchez,Humberto, PY - 2006/5/23/pubmed PY - 2006/9/30/medline PY - 2006/5/23/entrez SP - 113 EP - 20 JF - Gaceta medica de Mexico JO - Gac Med Mex VL - 142 IS - 2 N2 - BACKGROUND: The delay on the onset of specific treatment has several prognostic implications for psychotic patients. Duration of untreated psychosis (DUP) has been considered a prognostic variable. A longer DUP has been associated with a poor clinical outcome. OBJECTIVE: To determine the DUP in a sample of first-episode psychotic patients and its relationship with recovery and relapse on a one-year follow-up study. MATERIAL AND METHODS: A sample of 66 first-episode psychotic patients was recruited and divided according to their diagnoses in affective and non-affective psychoses. Diagnoses were obtained with SCAN and DUP was registered for each patient. A clinical assessment for psychotic and affective symptoms was performed using standardized instruments. RESULTS: All patient studied showed clinical improvement during follow-up. Patients with a longer DUP showed poorer psychosocial adjustment and lower recovery indexes. Treatment suspension was the main variable associated with relapse. CONCLUSIONS: DUP is an important prognostic variable. Early detection programs are required to decrease the period between illness onset, diagnosis and treatment in first-episode psychotic patients. SN - 0016-3813 UR - https://www.unboundmedicine.com/medline/citation/16711545/[Impact_of_the_duration_of_untreated_psychosis_among_patients_with_a_first_episode:_a_one_year_follow_up_study]_ L2 - https://medlineplus.gov/psychoticdisorders.html DB - PRIME DP - Unbound Medicine ER -