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Effects of low-fat hard cheese enriched with plant stanol esters on serum lipids and apolipoprotein B in mildly hypercholesterolaemic subjects.
Eur J Clin Nutr. 2006 Nov; 60(11):1253-7.EJ

Abstract

OBJECTIVE

To investigate the cholesterol-lowering effects of a low-fat cheese enriched with plant stanol esters in mildly hypercholesterolaemic subjects, as part of their normal diet.

DESIGN

A randomized double-blind parallel-group study.

SETTING

Valio Ltd, Helsinki.

SUBJECTS

Sixty-seven mildly hypercholesterolaemic volunteers (24 men, 43 women) participated in the study, which all of them completed.

INTERVENTIONS

The subjects were randomly assigned to the plant stanol ester group or the control group. During the 5-week intervention, the subjects in the stanol group consumed a cheese enriched with 2 g of plant stanols per day, and the subjects in the control group, a control cheese with no plant stanols.

RESULTS

In the stanol ester group, as compared to the control group, both serum total and low-density lipoprotein (LDL) cholesterol decreased significantly, that is, by 5.8% (-0.32 mmol/l, 95% CI -0.50 to -0.15 mmol/l, P < 0.001) and 10.3% (-0.36 mmol/l, 95% CI -0.53 to -0.18 mmol/l, P < 0.001), respectively. There were no significant changes in high-density lipoprotein cholesterol (HDL), triglycerides or apolipoprotein B concentrations between the groups.

CONCLUSION

Cheese enriched with 2 g of plant stanol in the form of fatty acid esters decreases serum total and LDL cholesterol significantly.

Authors+Show Affiliations

Valio Ltd, Helsinki, Finland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

16721398

Citation

Jauhiainen, T, et al. "Effects of Low-fat Hard Cheese Enriched With Plant Stanol Esters On Serum Lipids and Apolipoprotein B in Mildly Hypercholesterolaemic Subjects." European Journal of Clinical Nutrition, vol. 60, no. 11, 2006, pp. 1253-7.
Jauhiainen T, Salo P, Niittynen L, et al. Effects of low-fat hard cheese enriched with plant stanol esters on serum lipids and apolipoprotein B in mildly hypercholesterolaemic subjects. Eur J Clin Nutr. 2006;60(11):1253-7.
Jauhiainen, T., Salo, P., Niittynen, L., Poussa, T., & Korpela, R. (2006). Effects of low-fat hard cheese enriched with plant stanol esters on serum lipids and apolipoprotein B in mildly hypercholesterolaemic subjects. European Journal of Clinical Nutrition, 60(11), 1253-7.
Jauhiainen T, et al. Effects of Low-fat Hard Cheese Enriched With Plant Stanol Esters On Serum Lipids and Apolipoprotein B in Mildly Hypercholesterolaemic Subjects. Eur J Clin Nutr. 2006;60(11):1253-7. PubMed PMID: 16721398.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of low-fat hard cheese enriched with plant stanol esters on serum lipids and apolipoprotein B in mildly hypercholesterolaemic subjects. AU - Jauhiainen,T, AU - Salo,P, AU - Niittynen,L, AU - Poussa,T, AU - Korpela,R, Y1 - 2006/05/24/ PY - 2006/5/25/pubmed PY - 2007/1/24/medline PY - 2006/5/25/entrez SP - 1253 EP - 7 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 60 IS - 11 N2 - OBJECTIVE: To investigate the cholesterol-lowering effects of a low-fat cheese enriched with plant stanol esters in mildly hypercholesterolaemic subjects, as part of their normal diet. DESIGN: A randomized double-blind parallel-group study. SETTING: Valio Ltd, Helsinki. SUBJECTS: Sixty-seven mildly hypercholesterolaemic volunteers (24 men, 43 women) participated in the study, which all of them completed. INTERVENTIONS: The subjects were randomly assigned to the plant stanol ester group or the control group. During the 5-week intervention, the subjects in the stanol group consumed a cheese enriched with 2 g of plant stanols per day, and the subjects in the control group, a control cheese with no plant stanols. RESULTS: In the stanol ester group, as compared to the control group, both serum total and low-density lipoprotein (LDL) cholesterol decreased significantly, that is, by 5.8% (-0.32 mmol/l, 95% CI -0.50 to -0.15 mmol/l, P < 0.001) and 10.3% (-0.36 mmol/l, 95% CI -0.53 to -0.18 mmol/l, P < 0.001), respectively. There were no significant changes in high-density lipoprotein cholesterol (HDL), triglycerides or apolipoprotein B concentrations between the groups. CONCLUSION: Cheese enriched with 2 g of plant stanol in the form of fatty acid esters decreases serum total and LDL cholesterol significantly. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/16721398/Effects_of_low_fat_hard_cheese_enriched_with_plant_stanol_esters_on_serum_lipids_and_apolipoprotein_B_in_mildly_hypercholesterolaemic_subjects_ L2 - https://doi.org/10.1038/sj.ejcn.1602445 DB - PRIME DP - Unbound Medicine ER -