Tags

Type your tag names separated by a space and hit enter

Bacterial pneumonia in the AIDS patients.
West Afr J Med. 2006 Jan-Mar; 25(1):1-5.WA

Abstract

OBJECTIVE

To determine the incidence, microbiological pattern and prognostic factor of bacterial pneumonia in AIDS patients.

STUDY DESIGN

Prospective study of AIDS patients from July 2001 to Dec 2002.

METHODOLOGY

Adults AIDS patients on HAART drugs that develop acute fever, cough with bronchial breathing or lung crepitations had diagnostic evaluation that included chest x-ray, paired sputum microscopy, culture and sensitivity, paired blood culture and haematological profiles including CD4' cell count.

RESULTS

Twenty-one patients (22.6%), 9 males and 12 females developed community acquired pneumonia during this 16-month period. Pneumonia was confirmed in 9 patients (42.9%), presumed in 4 (19%) and probable in 8 (38%). Streptococcus pneumoniae accounted for 22% of the cases when immunity was less impaired. Staplhylococcus aureus accounted for another 22 % while Klebsiella pneumoniae, Pseudomonas aeraginosa and Escherichial coli were isolated in 11% each when immunity was severely compromised. Fifteen patients (71.4%) were successfully treated with routine antibiotics. Six cases (28.6%) died. All had anaemia, leucopoenia and low CD4 cell count. Four (66.7%) of this had positive bacterial culture with bacteremia in three of them.

CONCLUSION

Bacterial pneumonia in HIV-infected patients has similar presentation to that in the general population, Staphylococcus aureus and gram-negative bacilli especially Klebsiella pneumoniae were seen in a good proportion of the cases. Outcome of treatment was poor in the presence of positive bacterial culture, anemia, leucopoenia and very low CD4+ lymphocytes.

Authors+Show Affiliations

Department of Medicine, Faculty of Health Sciences, University of Ilorin P.M.B. 1515, Ilorin, Nigeria. salkaz2000@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16722349

Citation

Salami, A K., et al. "Bacterial Pneumonia in the AIDS Patients." West African Journal of Medicine, vol. 25, no. 1, 2006, pp. 1-5.
Salami AK, Olatunji PO, Oluboyo PO, et al. Bacterial pneumonia in the AIDS patients. West Afr J Med. 2006;25(1):1-5.
Salami, A. K., Olatunji, P. O., Oluboyo, P. O., Akanbi, A. A., & Fawibe, E. A. (2006). Bacterial pneumonia in the AIDS patients. West African Journal of Medicine, 25(1), 1-5.
Salami AK, et al. Bacterial Pneumonia in the AIDS Patients. West Afr J Med. 2006 Jan-Mar;25(1):1-5. PubMed PMID: 16722349.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bacterial pneumonia in the AIDS patients. AU - Salami,A K, AU - Olatunji,P O, AU - Oluboyo,P O, AU - Akanbi,A A,2nd AU - Fawibe,E A, PY - 2006/5/26/pubmed PY - 2006/9/27/medline PY - 2006/5/26/entrez SP - 1 EP - 5 JF - West African journal of medicine JO - West Afr J Med VL - 25 IS - 1 N2 - OBJECTIVE: To determine the incidence, microbiological pattern and prognostic factor of bacterial pneumonia in AIDS patients. STUDY DESIGN: Prospective study of AIDS patients from July 2001 to Dec 2002. METHODOLOGY: Adults AIDS patients on HAART drugs that develop acute fever, cough with bronchial breathing or lung crepitations had diagnostic evaluation that included chest x-ray, paired sputum microscopy, culture and sensitivity, paired blood culture and haematological profiles including CD4' cell count. RESULTS: Twenty-one patients (22.6%), 9 males and 12 females developed community acquired pneumonia during this 16-month period. Pneumonia was confirmed in 9 patients (42.9%), presumed in 4 (19%) and probable in 8 (38%). Streptococcus pneumoniae accounted for 22% of the cases when immunity was less impaired. Staplhylococcus aureus accounted for another 22 % while Klebsiella pneumoniae, Pseudomonas aeraginosa and Escherichial coli were isolated in 11% each when immunity was severely compromised. Fifteen patients (71.4%) were successfully treated with routine antibiotics. Six cases (28.6%) died. All had anaemia, leucopoenia and low CD4 cell count. Four (66.7%) of this had positive bacterial culture with bacteremia in three of them. CONCLUSION: Bacterial pneumonia in HIV-infected patients has similar presentation to that in the general population, Staphylococcus aureus and gram-negative bacilli especially Klebsiella pneumoniae were seen in a good proportion of the cases. Outcome of treatment was poor in the presence of positive bacterial culture, anemia, leucopoenia and very low CD4+ lymphocytes. SN - 0189-160X UR - https://www.unboundmedicine.com/medline/citation/16722349/Bacterial_pneumonia_in_the_AIDS_patients_ L2 - https://www.diseaseinfosearch.org/result/279 DB - PRIME DP - Unbound Medicine ER -