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Elderly patients with unexplained syncope: what should be considered a positive tilt test response?
Auton Neurosci. 2006 Jun 30; 126-127:169-73.AN

Abstract

INTRODUCTION

Syncope is a common problem and can lead to serious consequences in the elderly. Tilt test is useful to investigate recurrent syncope, but few studies have investigated the hemodynamic responses of this population to tilt test.

OBJECTIVE

To describe the tilt test responses of elderly patients with recurrent syncope of unknown origin and to determine the occurrence of altered cardiovascular autonomic function in a subset of those with the diagnosis of dysautonomic pattern to the tilt test.

METHODS

Elderly patients (n=165; >60 years old) who sought medical assistance because of recurrent syncope during 18 months were initially enrolled and submitted to a two-stage, nitroglycerin-potentiated tilt test. A subset of patients who presented with dysautonomic response to tilt test performed clinical autonomic tests.

RESULTS

The most frequent cause of syncope during tilt test was the dysautonomic pattern (43%), followed by mixed type neurocardiogenic syncope (35%). Most patients who remained asymptomatic during tilt test showed clear abnormal hemodynamic response during the exam.

CONCLUSION

Autonomic dysfunction, which can be found during tilt test, is probably an important cause of syncope in the elderly, regardless of the occurrence of symptoms during the tilt test.

Authors+Show Affiliations

de Castro RR
Cardiovascular and Autonomic Reactivity Laboratory, Syncope Unit and PROCEP, Hospital Pró-Cardíaco, Physiology and Pharmacology Department, Universidade Federal Fluminense, Rio de Janeiro, Brazil.
da Nobrega AC
No affiliation info available

MeSH

AgedAged, 80 and overBlood PressureFemaleGeriatric AssessmentHeart RateHemodynamicsHumansMaleProspective StudiesSensitivity and SpecificitySyncopeTilt-Table Test

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16725376

Citation

de Castro, Renata Rodrigues Teixeira, and Antonio Claudio Lucas da Nobrega. "Elderly Patients With Unexplained Syncope: what Should Be Considered a Positive Tilt Test Response?" Autonomic Neuroscience : Basic & Clinical, vol. 126-127, 2006, pp. 169-73.
de Castro RR, da Nobrega AC. Elderly patients with unexplained syncope: what should be considered a positive tilt test response? Auton Neurosci. 2006;126-127:169-73.
de Castro, R. R., & da Nobrega, A. C. (2006). Elderly patients with unexplained syncope: what should be considered a positive tilt test response? Autonomic Neuroscience : Basic & Clinical, 126-127, 169-73.
de Castro RR, da Nobrega AC. Elderly Patients With Unexplained Syncope: what Should Be Considered a Positive Tilt Test Response. Auton Neurosci. 2006 Jun 30;126-127:169-73. PubMed PMID: 16725376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Elderly patients with unexplained syncope: what should be considered a positive tilt test response? AU - de Castro,Renata Rodrigues Teixeira, AU - da Nobrega,Antonio Claudio Lucas, Y1 - 2006/05/24/ PY - 2005/10/29/received PY - 2006/04/15/revised PY - 2006/05/03/accepted PY - 2006/5/27/pubmed PY - 2006/9/26/medline PY - 2006/5/27/entrez SP - 169 EP - 73 JF - Autonomic neuroscience : basic & clinical JO - Auton Neurosci VL - 126-127 N2 - INTRODUCTION: Syncope is a common problem and can lead to serious consequences in the elderly. Tilt test is useful to investigate recurrent syncope, but few studies have investigated the hemodynamic responses of this population to tilt test. OBJECTIVE: To describe the tilt test responses of elderly patients with recurrent syncope of unknown origin and to determine the occurrence of altered cardiovascular autonomic function in a subset of those with the diagnosis of dysautonomic pattern to the tilt test. METHODS: Elderly patients (n=165; >60 years old) who sought medical assistance because of recurrent syncope during 18 months were initially enrolled and submitted to a two-stage, nitroglycerin-potentiated tilt test. A subset of patients who presented with dysautonomic response to tilt test performed clinical autonomic tests. RESULTS: The most frequent cause of syncope during tilt test was the dysautonomic pattern (43%), followed by mixed type neurocardiogenic syncope (35%). Most patients who remained asymptomatic during tilt test showed clear abnormal hemodynamic response during the exam. CONCLUSION: Autonomic dysfunction, which can be found during tilt test, is probably an important cause of syncope in the elderly, regardless of the occurrence of symptoms during the tilt test. SN - 1566-0702 UR - https://www.unboundmedicine.com/medline/citation/16725376/Elderly_patients_with_unexplained_syncope:_what_should_be_considered_a_positive_tilt_test_response DB - PRIME DP - Unbound Medicine ER -