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Pneumocystis carinii pneumonia complicating somatostatin therapy of Cushing's syndrome in a patient with metastatic pancreatic islet cell carcinoma and Zollinger-Ellison syndrome.
Am J Gastroenterol. 1991 Apr; 86(4):512-4.AJ

Abstract

Described is the case of a 73-yr-old woman with metastatic pancreatic islet carcinoma that manifested initially as Zollinger-Ellison syndrome followed by onset of endogenous Cushing's syndrome, who developed Pneumocystis carinii pneumonia while on therapy with a long-acting somatostatin analog. Although P. carinii pneumonia has been observed in patients with Cushing's syndrome associated with other conditions, this is the first reported case in a patient with Zollinger-Ellison syndrome. Heightened awareness of the possibility of opportunistic infections in patients receiving somatostatin therapy for Cushing's syndrome of any cause, particularly Zollinger-Ellison syndrome, may be warranted.

Authors+Show Affiliations

McQuillen DP
Maxwell Finland Laboratory for Infectious Diseases, Boston City Hospital, Massachusetts.
Schroy PC
No affiliation info available
Hesketh PJ
No affiliation info available
Sugar AM
No affiliation info available

MeSH

Adenoma, Islet CellAgedCushing SyndromeFemaleHumansNeoplasm MetastasisPancreatic NeoplasmsPneumonia, PneumocystisSomatostatinZollinger-Ellison Syndrome

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

1672788

Citation

McQuillen, D P., et al. "Pneumocystis Carinii Pneumonia Complicating Somatostatin Therapy of Cushing's Syndrome in a Patient With Metastatic Pancreatic Islet Cell Carcinoma and Zollinger-Ellison Syndrome." The American Journal of Gastroenterology, vol. 86, no. 4, 1991, pp. 512-4.
McQuillen DP, Schroy PC, Hesketh PJ, et al. Pneumocystis carinii pneumonia complicating somatostatin therapy of Cushing's syndrome in a patient with metastatic pancreatic islet cell carcinoma and Zollinger-Ellison syndrome. Am J Gastroenterol. 1991;86(4):512-4.
McQuillen, D. P., Schroy, P. C., Hesketh, P. J., & Sugar, A. M. (1991). Pneumocystis carinii pneumonia complicating somatostatin therapy of Cushing's syndrome in a patient with metastatic pancreatic islet cell carcinoma and Zollinger-Ellison syndrome. The American Journal of Gastroenterology, 86(4), 512-4.
McQuillen DP, et al. Pneumocystis Carinii Pneumonia Complicating Somatostatin Therapy of Cushing's Syndrome in a Patient With Metastatic Pancreatic Islet Cell Carcinoma and Zollinger-Ellison Syndrome. Am J Gastroenterol. 1991;86(4):512-4. PubMed PMID: 1672788.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pneumocystis carinii pneumonia complicating somatostatin therapy of Cushing's syndrome in a patient with metastatic pancreatic islet cell carcinoma and Zollinger-Ellison syndrome. AU - McQuillen,D P, AU - Schroy,P C, AU - Hesketh,P J, AU - Sugar,A M, PY - 1991/4/1/pubmed PY - 1991/4/1/medline PY - 1991/4/1/entrez SP - 512 EP - 4 JF - The American journal of gastroenterology JO - Am J Gastroenterol VL - 86 IS - 4 N2 - Described is the case of a 73-yr-old woman with metastatic pancreatic islet carcinoma that manifested initially as Zollinger-Ellison syndrome followed by onset of endogenous Cushing's syndrome, who developed Pneumocystis carinii pneumonia while on therapy with a long-acting somatostatin analog. Although P. carinii pneumonia has been observed in patients with Cushing's syndrome associated with other conditions, this is the first reported case in a patient with Zollinger-Ellison syndrome. Heightened awareness of the possibility of opportunistic infections in patients receiving somatostatin therapy for Cushing's syndrome of any cause, particularly Zollinger-Ellison syndrome, may be warranted. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/1672788/Pneumocystis_carinii_pneumonia_complicating_somatostatin_therapy_of_Cushing's_syndrome_in_a_patient_with_metastatic_pancreatic_islet_cell_carcinoma_and_Zollinger_Ellison_syndrome_ L2 - http://www.diseaseinfosearch.org/result/7600 DB - PRIME DP - Unbound Medicine ER -