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[Prevalence of inflammatory changes of gastric and/or duodenal mucosa among children and youth with gastroesophageal reflux].
Med Wieku Rozwoj. 2005 Oct-Dec; 9(4):637-45.MW

Abstract

THE AIM

The aim of the study was to estimate the prevalence of inflammatory changes of gastric and / or duodenal mucosa among children and youth with gastroesophageal reflux.

PATIENTS AND METHODS

Retrospective analysis of medical records of 143 patients aged from 2 to 18 years (mean 10.22 years), including 69 girls and 74 boys was performed. Gastroesophageal reflux was diagnosed on the basis of clinical features and 24-h oesophageal pH-metry. Upper gastrointestinal endoscopy was also simultaneously performed and biopsies of the antrum and duodenum were taken. Patients were divided into two age groups: group 1-36 children aged from 2 to 6 years and group II - 107 patients aged from 7 to 18 years. With regard to the intensity of gastroesophageal reflux patients were divided into two groups: A--71 patients with the percentage of time with pH < 4 between 4 and 10% and B--72 patients with the percentage of time with pH < 4 above 10%. Obtained results were analysed statistically.

RESULTS

Gastritis and/or duodenitis was observed in 121 patients (84.7%), including mild in 84 patients (69.4%), moderate in 32 patients (26.5%) and severe in 5 children (4.1%). Of these patients, 29 (20.3%) were Helicobacter pylori positive. There was no statistically significant difference between prevalence of gastritis and/or duodenitis and the degree of gastroesophageal reflux.

CONCLUSIONS

Mostly mild gastritis and/or duodenitis were observed in the majority of children and youth with gastroesophageal reflux regardless of the Helicobacter pylori status. The prevalence of gastritis and/or duodenitis does not correlate with the intensity of the gastroesophageal reflux in children and youth.

Authors+Show Affiliations

Katedra i Klinika Pediatrii, Alergologii i Gastroenterologii, Collegium Medicum im. L. Rydygiera, ul. M. Skłodowskiej-Curie 9, 85-094 Bydgoszcz, Poland. klped@cm.umk.plNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

pol

PubMed ID

16733274

Citation

Nowak, Aleksandra, et al. "[Prevalence of Inflammatory Changes of Gastric And/or Duodenal Mucosa Among Children and Youth With Gastroesophageal Reflux]." Medycyna Wieku Rozwojowego, vol. 9, no. 4, 2005, pp. 637-45.
Nowak A, Brazowski J, Szaflarska-Popławska A. [Prevalence of inflammatory changes of gastric and/or duodenal mucosa among children and youth with gastroesophageal reflux]. Med Wieku Rozwoj. 2005;9(4):637-45.
Nowak, A., Brazowski, J., & Szaflarska-Popławska, A. (2005). [Prevalence of inflammatory changes of gastric and/or duodenal mucosa among children and youth with gastroesophageal reflux]. Medycyna Wieku Rozwojowego, 9(4), 637-45.
Nowak A, Brazowski J, Szaflarska-Popławska A. [Prevalence of Inflammatory Changes of Gastric And/or Duodenal Mucosa Among Children and Youth With Gastroesophageal Reflux]. Med Wieku Rozwoj. 2005 Oct-Dec;9(4):637-45. PubMed PMID: 16733274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Prevalence of inflammatory changes of gastric and/or duodenal mucosa among children and youth with gastroesophageal reflux]. AU - Nowak,Aleksandra, AU - Brazowski,Jerzy, AU - Szaflarska-Popławska,Anna, PY - 2006/5/31/pubmed PY - 2006/8/3/medline PY - 2006/5/31/entrez SP - 637 EP - 45 JF - Medycyna wieku rozwojowego JO - Med Wieku Rozwoj VL - 9 IS - 4 N2 - THE AIM: The aim of the study was to estimate the prevalence of inflammatory changes of gastric and / or duodenal mucosa among children and youth with gastroesophageal reflux. PATIENTS AND METHODS: Retrospective analysis of medical records of 143 patients aged from 2 to 18 years (mean 10.22 years), including 69 girls and 74 boys was performed. Gastroesophageal reflux was diagnosed on the basis of clinical features and 24-h oesophageal pH-metry. Upper gastrointestinal endoscopy was also simultaneously performed and biopsies of the antrum and duodenum were taken. Patients were divided into two age groups: group 1-36 children aged from 2 to 6 years and group II - 107 patients aged from 7 to 18 years. With regard to the intensity of gastroesophageal reflux patients were divided into two groups: A--71 patients with the percentage of time with pH < 4 between 4 and 10% and B--72 patients with the percentage of time with pH < 4 above 10%. Obtained results were analysed statistically. RESULTS: Gastritis and/or duodenitis was observed in 121 patients (84.7%), including mild in 84 patients (69.4%), moderate in 32 patients (26.5%) and severe in 5 children (4.1%). Of these patients, 29 (20.3%) were Helicobacter pylori positive. There was no statistically significant difference between prevalence of gastritis and/or duodenitis and the degree of gastroesophageal reflux. CONCLUSIONS: Mostly mild gastritis and/or duodenitis were observed in the majority of children and youth with gastroesophageal reflux regardless of the Helicobacter pylori status. The prevalence of gastritis and/or duodenitis does not correlate with the intensity of the gastroesophageal reflux in children and youth. UR - https://www.unboundmedicine.com/medline/citation/16733274/[Prevalence_of_inflammatory_changes_of_gastric_and/or_duodenal_mucosa_among_children_and_youth_with_gastroesophageal_reflux]_ L2 - https://www.diseaseinfosearch.org/result/2996 DB - PRIME DP - Unbound Medicine ER -