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Dietary intake of carotenoids and retinol and the risk of acute myocardial infarction in Italy.
Free Radic Res. 2006 Jun; 40(6):659-64.FR

Abstract

BACKGROUND

Carotenoids may reduce the risk of coronary heart disease through their antioxidant properties, but the results of epidemiological studies are controversial. We analysed the relation between the intake of selected carotenoids and retinol and risk of acute myocardial infarction (AMI).

METHODS

A case-control study was conducted in Milan, Italy, in 1995-2003. Cases were 760 patients with nonfatal AMI, and controls 682 patients admitted to hospital.

RESULTS

The risk of AMI decreased with increasing intake of alpha-carotene (odds ratios, OR = 0.71, 95% confidence intervals, CI 0.51-0.98, for the highest vs the lowest quartile of intake), beta-carotene (OR = 0.71, 95% CI 0.50-1.01) and beta-criptoxanthin (OR = 0.64, 95% CI 0.46-0.88). No associations emerged for total carotenoids, lycopene, lutein plus zeaxanthin and retinol.

CONCLUSIONS

Our study suggests a weak protective effect of alpha-carotene, beta-carotene and beta-criptoxanthin on the risk of AMI. It also indicates that total carotenoids, lycopene, lutein plus zeaxanthin and retinol were not related to the risk of the disease.

Authors+Show Affiliations

Istituto di Ricerche Farmacologiche Mario Negri, Via Eritrea 62, Milan, 20157, Italy. tavani@marionegri.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16753844

Citation

Tavani, Alessandra, et al. "Dietary Intake of Carotenoids and Retinol and the Risk of Acute Myocardial Infarction in Italy." Free Radical Research, vol. 40, no. 6, 2006, pp. 659-64.
Tavani A, Gallus S, Negri E, et al. Dietary intake of carotenoids and retinol and the risk of acute myocardial infarction in Italy. Free Radic Res. 2006;40(6):659-64.
Tavani, A., Gallus, S., Negri, E., Parpinel, M., & La Vecchia, C. (2006). Dietary intake of carotenoids and retinol and the risk of acute myocardial infarction in Italy. Free Radical Research, 40(6), 659-64.
Tavani A, et al. Dietary Intake of Carotenoids and Retinol and the Risk of Acute Myocardial Infarction in Italy. Free Radic Res. 2006;40(6):659-64. PubMed PMID: 16753844.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary intake of carotenoids and retinol and the risk of acute myocardial infarction in Italy. AU - Tavani,Alessandra, AU - Gallus,Silvano, AU - Negri,Eva, AU - Parpinel,Maria, AU - La Vecchia,Carlo, PY - 2006/6/7/pubmed PY - 2006/8/2/medline PY - 2006/6/7/entrez SP - 659 EP - 64 JF - Free radical research JO - Free Radic. Res. VL - 40 IS - 6 N2 - BACKGROUND: Carotenoids may reduce the risk of coronary heart disease through their antioxidant properties, but the results of epidemiological studies are controversial. We analysed the relation between the intake of selected carotenoids and retinol and risk of acute myocardial infarction (AMI). METHODS: A case-control study was conducted in Milan, Italy, in 1995-2003. Cases were 760 patients with nonfatal AMI, and controls 682 patients admitted to hospital. RESULTS: The risk of AMI decreased with increasing intake of alpha-carotene (odds ratios, OR = 0.71, 95% confidence intervals, CI 0.51-0.98, for the highest vs the lowest quartile of intake), beta-carotene (OR = 0.71, 95% CI 0.50-1.01) and beta-criptoxanthin (OR = 0.64, 95% CI 0.46-0.88). No associations emerged for total carotenoids, lycopene, lutein plus zeaxanthin and retinol. CONCLUSIONS: Our study suggests a weak protective effect of alpha-carotene, beta-carotene and beta-criptoxanthin on the risk of AMI. It also indicates that total carotenoids, lycopene, lutein plus zeaxanthin and retinol were not related to the risk of the disease. SN - 1071-5762 UR - https://www.unboundmedicine.com/medline/citation/16753844/Dietary_intake_of_carotenoids_and_retinol_and_the_risk_of_acute_myocardial_infarction_in_Italy_ L2 - http://www.tandfonline.com/doi/full/10.1080/10715760600615649 DB - PRIME DP - Unbound Medicine ER -