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Excellent response to apomorphine in Parkinsonism with optic atrophy unresponsive to oral antiparkinsonian medication.
Mov Disord. 2006 Sep; 21(9):1523-5.MD

Abstract

Two patients presented with the cardinal symptoms of Parkinson's disease (PD), which had developed slowly and progressively. One patient underwent brain imaging of the dopaminergic system, the results of which were compatible with PD. However, both patients showed no response to L-dopa or oral dopaminergic medication. They also had optic nerve atrophy of unknown etiology. The severe motor symptoms of both patients were conspicuously alleviated by apomorphine delivered subcutaneously. One patient underwent bilateral subthalamic nucleus deep brain stimulation, which also proved effective.

Authors+Show Affiliations

Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians University, Munich, Germany. angela.deutschlaender@med.uni-muenchen.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

16755578

Citation

Deutschländer, Angela, et al. "Excellent Response to Apomorphine in Parkinsonism With Optic Atrophy Unresponsive to Oral Antiparkinsonian Medication." Movement Disorders : Official Journal of the Movement Disorder Society, vol. 21, no. 9, 2006, pp. 1523-5.
Deutschländer A, Asmus F, Marelli E, et al. Excellent response to apomorphine in Parkinsonism with optic atrophy unresponsive to oral antiparkinsonian medication. Mov Disord. 2006;21(9):1523-5.
Deutschländer, A., Asmus, F., Marelli, E., Klopstock, T., Gasser, T., & Bötzel, K. (2006). Excellent response to apomorphine in Parkinsonism with optic atrophy unresponsive to oral antiparkinsonian medication. Movement Disorders : Official Journal of the Movement Disorder Society, 21(9), 1523-5.
Deutschländer A, et al. Excellent Response to Apomorphine in Parkinsonism With Optic Atrophy Unresponsive to Oral Antiparkinsonian Medication. Mov Disord. 2006;21(9):1523-5. PubMed PMID: 16755578.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Excellent response to apomorphine in Parkinsonism with optic atrophy unresponsive to oral antiparkinsonian medication. AU - Deutschländer,Angela, AU - Asmus,Friedrich, AU - Marelli,Elena, AU - Klopstock,Thomas, AU - Gasser,Thomas, AU - Bötzel,Kai, PY - 2006/6/7/pubmed PY - 2007/2/3/medline PY - 2006/6/7/entrez SP - 1523 EP - 5 JF - Movement disorders : official journal of the Movement Disorder Society JO - Mov Disord VL - 21 IS - 9 N2 - Two patients presented with the cardinal symptoms of Parkinson's disease (PD), which had developed slowly and progressively. One patient underwent brain imaging of the dopaminergic system, the results of which were compatible with PD. However, both patients showed no response to L-dopa or oral dopaminergic medication. They also had optic nerve atrophy of unknown etiology. The severe motor symptoms of both patients were conspicuously alleviated by apomorphine delivered subcutaneously. One patient underwent bilateral subthalamic nucleus deep brain stimulation, which also proved effective. SN - 0885-3185 UR - https://www.unboundmedicine.com/medline/citation/16755578/Excellent_response_to_apomorphine_in_Parkinsonism_with_optic_atrophy_unresponsive_to_oral_antiparkinsonian_medication_ L2 - https://doi.org/10.1002/mds.20975 DB - PRIME DP - Unbound Medicine ER -