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The yield of capsule endoscopy in patients with abdominal pain or diarrhea.
Endoscopy. 2006 May; 38(5):498-502.E

Abstract

BACKGROUND AND STUDY AIMS

Capsule endoscopy, proven effective for evaluation of obscure gastrointestinal bleeding and suspected Crohn's disease, is increasingly used to investigate other small-intestine disorders, but its yield for other indications is not well known. We sought to evaluate its yield and findings for abdominal pain or diarrhea.

PATIENTS AND METHODS

Medical records of patients with abdominal pain or diarrhea (> 6 weeks' duration) who underwent capsule endoscopy between August 2001 and June 2004 were retrospectively reviewed for demographic data, indications, findings, diagnoses, complications, and radiologic studies. All patients had previous endoscopic or radiologic examinations (colonoscopy, enteroscopy, upper endoscopy, small-bowel series, computed tomography enterography, or computed tomography) demonstrating no abnormalities sufficient for diagnosis.

RESULTS

64 patients (26 men; 38 women; mean age, 43 years; age range, 19 - 83 years) who met study criteria had 68 capsule endoscopy studies. Indications were abdominal pain (35 patients), diarrhea (14), or both (15). Complete small-bowel visualization with identification of the cecum was achieved in 81 %; yield of positive findings was 9 % (6 patients). By indications, the yield was 6 % for abdominal pain, 14 % for diarrhea, and 13 % for both. Diagnoses included Crohn's disease (3), enteropathy induced by nonsteroidal anti-inflammatory drugs (2), and submucosal tumor (1). Capsule retention occurred in two patients, requiring surgical removal.

CONCLUSIONS

Capsule endoscopy had a low yield for evaluation of abdominal pain or diarrhea and cannot be recommended as a first-line test without further study. Nonetheless, it facilitated diagnosis in 9 % of patients with negative endoscopic and radiologic examinations.

Authors+Show Affiliations

Division of Gastroenterology and Hepatology, Mayo Clinic, Scottsdale, Arizona 85259, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16767586

Citation

Fry, L C., et al. "The Yield of Capsule Endoscopy in Patients With Abdominal Pain or Diarrhea." Endoscopy, vol. 38, no. 5, 2006, pp. 498-502.
Fry LC, Carey EJ, Shiff AD, et al. The yield of capsule endoscopy in patients with abdominal pain or diarrhea. Endoscopy. 2006;38(5):498-502.
Fry, L. C., Carey, E. J., Shiff, A. D., Heigh, R. I., Sharma, V. K., Post, J. K., Hentz, J. G., Fleischer, D. E., & Leighton, J. A. (2006). The yield of capsule endoscopy in patients with abdominal pain or diarrhea. Endoscopy, 38(5), 498-502.
Fry LC, et al. The Yield of Capsule Endoscopy in Patients With Abdominal Pain or Diarrhea. Endoscopy. 2006;38(5):498-502. PubMed PMID: 16767586.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The yield of capsule endoscopy in patients with abdominal pain or diarrhea. AU - Fry,L C, AU - Carey,E J, AU - Shiff,A D, AU - Heigh,R I, AU - Sharma,V K, AU - Post,J K, AU - Hentz,J G, AU - Fleischer,D E, AU - Leighton,J A, PY - 2006/6/13/pubmed PY - 2006/10/27/medline PY - 2006/6/13/entrez SP - 498 EP - 502 JF - Endoscopy JO - Endoscopy VL - 38 IS - 5 N2 - BACKGROUND AND STUDY AIMS: Capsule endoscopy, proven effective for evaluation of obscure gastrointestinal bleeding and suspected Crohn's disease, is increasingly used to investigate other small-intestine disorders, but its yield for other indications is not well known. We sought to evaluate its yield and findings for abdominal pain or diarrhea. PATIENTS AND METHODS: Medical records of patients with abdominal pain or diarrhea (> 6 weeks' duration) who underwent capsule endoscopy between August 2001 and June 2004 were retrospectively reviewed for demographic data, indications, findings, diagnoses, complications, and radiologic studies. All patients had previous endoscopic or radiologic examinations (colonoscopy, enteroscopy, upper endoscopy, small-bowel series, computed tomography enterography, or computed tomography) demonstrating no abnormalities sufficient for diagnosis. RESULTS: 64 patients (26 men; 38 women; mean age, 43 years; age range, 19 - 83 years) who met study criteria had 68 capsule endoscopy studies. Indications were abdominal pain (35 patients), diarrhea (14), or both (15). Complete small-bowel visualization with identification of the cecum was achieved in 81 %; yield of positive findings was 9 % (6 patients). By indications, the yield was 6 % for abdominal pain, 14 % for diarrhea, and 13 % for both. Diagnoses included Crohn's disease (3), enteropathy induced by nonsteroidal anti-inflammatory drugs (2), and submucosal tumor (1). Capsule retention occurred in two patients, requiring surgical removal. CONCLUSIONS: Capsule endoscopy had a low yield for evaluation of abdominal pain or diarrhea and cannot be recommended as a first-line test without further study. Nonetheless, it facilitated diagnosis in 9 % of patients with negative endoscopic and radiologic examinations. SN - 0013-726X UR - https://www.unboundmedicine.com/medline/citation/16767586/The_yield_of_capsule_endoscopy_in_patients_with_abdominal_pain_or_diarrhea_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2006-925340 DB - PRIME DP - Unbound Medicine ER -