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Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome.
Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):193-205.BP

Abstract

Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, and its definition remains fluid and controversial. PCOS is characterized by clinical and/or biochemical hyperandrogenism, and is frequently accompanied by ovulatory dysfunction and polycystic ovaries. PCOS is a diagnosis of exclusion, with other androgen excess and related disorders to be excluded. The prevalence of PCOS is 6.5-8.0% of unselected women of reproductive age, using the NIH 1990 criteria. Genetically, PCOS is a common, complex disorder. Despite repeated attempts to identify the putative gene or genes responsible for this disorder, the PCOS gene(s) remain elusive.

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Authors+Show Affiliations

Goodarzi MO
Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Medical Genetics Institute, Los Angeles, CA, USA.
Azziz R
No affiliation info available

MeSH

AdolescentAdultEuropeFemaleHumansPhenotypePolycystic Ovary SyndromePrevalence

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Review

Language

eng

PubMed ID

16772151

Citation

Goodarzi, Mark O., and Ricardo Azziz. "Diagnosis, Epidemiology, and Genetics of the Polycystic Ovary Syndrome." Best Practice & Research. Clinical Endocrinology & Metabolism, vol. 20, no. 2, 2006, pp. 193-205.
Goodarzi MO, Azziz R. Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome. Best Pract Res Clin Endocrinol Metab. 2006;20(2):193-205.
Goodarzi, M. O., & Azziz, R. (2006). Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome. Best Practice & Research. Clinical Endocrinology & Metabolism, 20(2), 193-205.
Goodarzi MO, Azziz R. Diagnosis, Epidemiology, and Genetics of the Polycystic Ovary Syndrome. Best Pract Res Clin Endocrinol Metab. 2006;20(2):193-205. PubMed PMID: 16772151.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome. AU - Goodarzi,Mark O, AU - Azziz,Ricardo, PY - 2006/6/15/pubmed PY - 2006/8/12/medline PY - 2006/6/15/entrez SP - 193 EP - 205 JF - Best practice & research. Clinical endocrinology & metabolism JO - Best Pract Res Clin Endocrinol Metab VL - 20 IS - 2 N2 - Polycystic ovary syndrome (PCOS) is a heterogeneous disorder, and its definition remains fluid and controversial. PCOS is characterized by clinical and/or biochemical hyperandrogenism, and is frequently accompanied by ovulatory dysfunction and polycystic ovaries. PCOS is a diagnosis of exclusion, with other androgen excess and related disorders to be excluded. The prevalence of PCOS is 6.5-8.0% of unselected women of reproductive age, using the NIH 1990 criteria. Genetically, PCOS is a common, complex disorder. Despite repeated attempts to identify the putative gene or genes responsible for this disorder, the PCOS gene(s) remain elusive. SN - 1521-690X UR - https://www.unboundmedicine.com/medline/citation/16772151/Diagnosis_epidemiology_and_genetics_of_the_polycystic_ovary_syndrome_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1521-690X(06)00022-4 DB - PRIME DP - Unbound Medicine ER -