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Treatment of hirsutism and acne in hyperandrogenism.
Best Pract Res Clin Endocrinol Metab. 2006 Jun; 20(2):221-34.BP

Abstract

Hirsutism and acne are common and highly distressing complaints in women with polycystic ovary syndrome (PCOS). Drugs are only partially effective on terminalized hairs, and removal of these hairs is usually required. Therefore, management of hirsutism is generally based upon a dual approach: a pharmacological therapy to reduce androgen secretion and/or androgen action, and removal of terminal hair already present. Ovarian suppression of androgen secretion with oral contraceptives is widely used in these women, but its efficacy appears limited. The most effective medical therapy for hirsutism is by anti-androgen drugs. Electrolysis and laser photothermolysis are considered the most effective cosmetic procedures, although the effects of these methods should not be considered permanent. Acne may be treated with different tools, according to the severity of the condition and other characteristics of the patient. These tools include topical and systemic retinoids and antibiotics, topical antibacterial agents, androgen suppression by oral contraceptives, and anti-androgen drugs.

Authors+Show Affiliations

Division of Endocrinology and Metabolic Diseases, University of Verona, Ospedale Maggiore, P. le Stefani 1, 37126 Verona, Italy. moghetti@iol.itNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16772153

Citation

Moghetti, Paolo, and Vincenzo Toscano. "Treatment of Hirsutism and Acne in Hyperandrogenism." Best Practice & Research. Clinical Endocrinology & Metabolism, vol. 20, no. 2, 2006, pp. 221-34.
Moghetti P, Toscano V. Treatment of hirsutism and acne in hyperandrogenism. Best Pract Res Clin Endocrinol Metab. 2006;20(2):221-34.
Moghetti, P., & Toscano, V. (2006). Treatment of hirsutism and acne in hyperandrogenism. Best Practice & Research. Clinical Endocrinology & Metabolism, 20(2), 221-34.
Moghetti P, Toscano V. Treatment of Hirsutism and Acne in Hyperandrogenism. Best Pract Res Clin Endocrinol Metab. 2006;20(2):221-34. PubMed PMID: 16772153.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of hirsutism and acne in hyperandrogenism. AU - Moghetti,Paolo, AU - Toscano,Vincenzo, PY - 2006/6/15/pubmed PY - 2006/8/12/medline PY - 2006/6/15/entrez SP - 221 EP - 34 JF - Best practice & research. Clinical endocrinology & metabolism JO - Best Pract Res Clin Endocrinol Metab VL - 20 IS - 2 N2 - Hirsutism and acne are common and highly distressing complaints in women with polycystic ovary syndrome (PCOS). Drugs are only partially effective on terminalized hairs, and removal of these hairs is usually required. Therefore, management of hirsutism is generally based upon a dual approach: a pharmacological therapy to reduce androgen secretion and/or androgen action, and removal of terminal hair already present. Ovarian suppression of androgen secretion with oral contraceptives is widely used in these women, but its efficacy appears limited. The most effective medical therapy for hirsutism is by anti-androgen drugs. Electrolysis and laser photothermolysis are considered the most effective cosmetic procedures, although the effects of these methods should not be considered permanent. Acne may be treated with different tools, according to the severity of the condition and other characteristics of the patient. These tools include topical and systemic retinoids and antibiotics, topical antibacterial agents, androgen suppression by oral contraceptives, and anti-androgen drugs. SN - 1521-690X UR - https://www.unboundmedicine.com/medline/citation/16772153/Treatment_of_hirsutism_and_acne_in_hyperandrogenism_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1521-690X(06)00025-X DB - PRIME DP - Unbound Medicine ER -