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Fulfilling the promise of insulin pump therapy in childhood diabetes.
Pediatr Diabetes. 2006 Aug; 7 Suppl 4:4-10.PD

Abstract

Although insulin pump or continuous subcutaneous insulin infusion (CSII) treatment was first introduced more than 25 yr ago, very few children and adolescents with type 1 diabetes mellitus (T1DM) utilized this therapy until recently. In this paper, we review many of the early triumphs, as well as a number of unexpected obstacles that were encountered in applying CSII in the treatment of T1DM. Nevertheless, the greater urgency to obtain optimal control of diabetes following the Diabetes Control and Complications Trial (DCCT), the introduction of rapid-acting insulin analogs and improvements in pump technology have led to a sharp increase in the use of this therapy in youth with T1DM and, generally, favorable outcomes. Moreover, the recent introduction of continuous glucose monitoring systems (CGMSs) offers the prospect of finally realizing the full potential of insulin pump therapy to normalize hemoglobin A1c (HbAlc) levels with minimal risk of hypoglycemia.

Authors+Show Affiliations

Department of Pediatrics and the General Clinical Research Center, Yale University School of Medicine, New Haven, CT 06520, USA. willaim.tamborlane@yale.edu

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

16774611

Citation

Tamborlane, William V.. "Fulfilling the Promise of Insulin Pump Therapy in Childhood Diabetes." Pediatric Diabetes, vol. 7 Suppl 4, 2006, pp. 4-10.
Tamborlane WV. Fulfilling the promise of insulin pump therapy in childhood diabetes. Pediatr Diabetes. 2006;7 Suppl 4:4-10.
Tamborlane, W. V. (2006). Fulfilling the promise of insulin pump therapy in childhood diabetes. Pediatric Diabetes, 7 Suppl 4, 4-10.
Tamborlane WV. Fulfilling the Promise of Insulin Pump Therapy in Childhood Diabetes. Pediatr Diabetes. 2006;7 Suppl 4:4-10. PubMed PMID: 16774611.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fulfilling the promise of insulin pump therapy in childhood diabetes. A1 - Tamborlane,William V, PY - 2006/6/16/pubmed PY - 2006/12/9/medline PY - 2006/6/16/entrez SP - 4 EP - 10 JF - Pediatric diabetes JO - Pediatr Diabetes VL - 7 Suppl 4 N2 - Although insulin pump or continuous subcutaneous insulin infusion (CSII) treatment was first introduced more than 25 yr ago, very few children and adolescents with type 1 diabetes mellitus (T1DM) utilized this therapy until recently. In this paper, we review many of the early triumphs, as well as a number of unexpected obstacles that were encountered in applying CSII in the treatment of T1DM. Nevertheless, the greater urgency to obtain optimal control of diabetes following the Diabetes Control and Complications Trial (DCCT), the introduction of rapid-acting insulin analogs and improvements in pump technology have led to a sharp increase in the use of this therapy in youth with T1DM and, generally, favorable outcomes. Moreover, the recent introduction of continuous glucose monitoring systems (CGMSs) offers the prospect of finally realizing the full potential of insulin pump therapy to normalize hemoglobin A1c (HbAlc) levels with minimal risk of hypoglycemia. SN - 1399-543X UR - https://www.unboundmedicine.com/medline/citation/16774611/Fulfilling_the_promise_of_insulin_pump_therapy_in_childhood_diabetes_ L2 - https://doi.org/10.1111/j.1399-543X.2006.00171.x DB - PRIME DP - Unbound Medicine ER -