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[The colorful clinical spectrum of cerebral toxoplasmosis in five HIV positive cases: what comes out of Pandora's box?].
Mikrobiyol Bul 2006 Jan-Apr; 40(1-2):85-92MB

Abstract

In patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), the most common cause of focal intracranial lesion is Toxoplasma gondii infection. T. gondii encephalitis is an easily and effectively treatable disease, with promising outcomes. T. gondii has the potential to form a focal infection niche anywhere in the central nervous system, thus allowing for a colorful clinical picture. In this report, we attempted to present five HIV/AIDS cases with central nervous system toxoplasmosis demonstrating five different neurological presentations. The ages, gender and clinical findings of the patients who were admitted to our Infectious Diseases Clinics were as follows; 35 years old male patient with delirium, 49 years old male patient with focal dystony, 32 years old female patient with facial paralysis and monoparalysis, 53 years old male patient with Wernicke syndrome, 32 years old male patient with epilepsy. Cerebral toxoplasmosis were diagnosed by clinical findings and imaging techniques. The patients were treated with trimetoprim-sulfametoxazol (TMP-SMZ) and haloperidol, only TMP-SMZ, clindamycin and daraprim, TMP-SMZ and levotiracetam, TMP-SMZ and phenytoin, respectively, with recovery in neurological and radiological symptoms. In conclusion, until proven otherwise, HIV/AIDS patients presenting with focal neurological complaints should be accepted as having central nervous system toxoplasmosis.

Authors+Show Affiliations

Hacettepe Universitesi Tip Fakültesi, Nöroloji Anabilim Dali, Ankara.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

tur

PubMed ID

16775962

Citation

Kurne, Asli, et al. "[The Colorful Clinical Spectrum of Cerebral Toxoplasmosis in Five HIV Positive Cases: what Comes Out of Pandora's Box?]." Mikrobiyoloji Bulteni, vol. 40, no. 1-2, 2006, pp. 85-92.
Kurne A, Ozkaya G, Karlioğuz K, et al. [The colorful clinical spectrum of cerebral toxoplasmosis in five HIV positive cases: what comes out of Pandora's box?]. Mikrobiyol Bul. 2006;40(1-2):85-92.
Kurne, A., Ozkaya, G., Karlioğuz, K., Shorbagi, A., Ustaçelebi, S., Karabudak, R., & Unal, S. (2006). [The colorful clinical spectrum of cerebral toxoplasmosis in five HIV positive cases: what comes out of Pandora's box?]. Mikrobiyoloji Bulteni, 40(1-2), pp. 85-92.
Kurne A, et al. [The Colorful Clinical Spectrum of Cerebral Toxoplasmosis in Five HIV Positive Cases: what Comes Out of Pandora's Box?]. Mikrobiyol Bul. 2006;40(1-2):85-92. PubMed PMID: 16775962.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The colorful clinical spectrum of cerebral toxoplasmosis in five HIV positive cases: what comes out of Pandora's box?]. AU - Kurne,Asli, AU - Ozkaya,Gülşen, AU - Karlioğuz,Kader, AU - Shorbagi,Ali, AU - Ustaçelebi,Semsettin, AU - Karabudak,Rana, AU - Unal,Serhat, PY - 2006/6/17/pubmed PY - 2007/3/28/medline PY - 2006/6/17/entrez SP - 85 EP - 92 JF - Mikrobiyoloji bulteni JO - Mikrobiyol Bul VL - 40 IS - 1-2 N2 - In patients with human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS), the most common cause of focal intracranial lesion is Toxoplasma gondii infection. T. gondii encephalitis is an easily and effectively treatable disease, with promising outcomes. T. gondii has the potential to form a focal infection niche anywhere in the central nervous system, thus allowing for a colorful clinical picture. In this report, we attempted to present five HIV/AIDS cases with central nervous system toxoplasmosis demonstrating five different neurological presentations. The ages, gender and clinical findings of the patients who were admitted to our Infectious Diseases Clinics were as follows; 35 years old male patient with delirium, 49 years old male patient with focal dystony, 32 years old female patient with facial paralysis and monoparalysis, 53 years old male patient with Wernicke syndrome, 32 years old male patient with epilepsy. Cerebral toxoplasmosis were diagnosed by clinical findings and imaging techniques. The patients were treated with trimetoprim-sulfametoxazol (TMP-SMZ) and haloperidol, only TMP-SMZ, clindamycin and daraprim, TMP-SMZ and levotiracetam, TMP-SMZ and phenytoin, respectively, with recovery in neurological and radiological symptoms. In conclusion, until proven otherwise, HIV/AIDS patients presenting with focal neurological complaints should be accepted as having central nervous system toxoplasmosis. SN - 0374-9096 UR - https://www.unboundmedicine.com/medline/citation/16775962/[The_colorful_clinical_spectrum_of_cerebral_toxoplasmosis_in_five_HIV_positive_cases:_what_comes_out_of_Pandora's_box]_ L2 - http://www.diseaseinfosearch.org/result/9735 DB - PRIME DP - Unbound Medicine ER -