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Decline in suicidal ideation among patients with MDD is preceded by decline in depression and hopelessness.
J Affect Disord. 2006 Oct; 95(1-3):95-102.JA

Abstract

BACKGROUND

Suicidal ideation is likely to represent a phase preceding suicidal acts among most suicidal patients with major depressive disorder (MDD). Factors predicting reversal of the suicidal process are unknown. Our aim was to test the hypothesis that a decline in suicidal ideation is preceded by a decline in hopelessness among patients with MDD.

METHOD

Of the 269 Vantaa Depression Study patients with DSM-IV MDD, 103 patients scored > or = 6 points at baseline on the Scale for Suicidal Ideation (SSI). Seventy of these patients were followed-up weekly either until they scored zero points on the SSI, or up to 26 weeks.

RESULTS

The median duration for a decline of suicidal ideation to zero was 2.2 months after baseline. The level of baseline suicidal ideation, depressive symptoms, and the presence of any personality disorder predicted duration of suicidal ideation. A decline in both depression (BDI) and hopelessness (HS) independently predicted a decline in suicidal ideation.

LIMITATIONS

Due to study design, we do not know if suicidal ideation relapsed after the first time the patient reached zero score in the SSI.

CONCLUSIONS

Among patients with major depressive disorder having suicidal ideation, the decline in suicidal ideation is independently predicted by preceding declines in the levels of both depressive symptoms as well as hopelessness. The findings are consistent with possible causal roles of declines in depression and hopelessness in reversing the suicidal process.

Authors+Show Affiliations

Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16780959

Citation

Sokero, Petteri, et al. "Decline in Suicidal Ideation Among Patients With MDD Is Preceded By Decline in Depression and Hopelessness." Journal of Affective Disorders, vol. 95, no. 1-3, 2006, pp. 95-102.
Sokero P, Eerola M, Rytsälä H, et al. Decline in suicidal ideation among patients with MDD is preceded by decline in depression and hopelessness. J Affect Disord. 2006;95(1-3):95-102.
Sokero, P., Eerola, M., Rytsälä, H., Melartin, T., Leskelä, U., Lestelä-Mielonen, P., & Isometsä, E. (2006). Decline in suicidal ideation among patients with MDD is preceded by decline in depression and hopelessness. Journal of Affective Disorders, 95(1-3), 95-102.
Sokero P, et al. Decline in Suicidal Ideation Among Patients With MDD Is Preceded By Decline in Depression and Hopelessness. J Affect Disord. 2006;95(1-3):95-102. PubMed PMID: 16780959.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Decline in suicidal ideation among patients with MDD is preceded by decline in depression and hopelessness. AU - Sokero,Petteri, AU - Eerola,Mervi, AU - Rytsälä,Heikki, AU - Melartin,Tarja, AU - Leskelä,Ulla, AU - Lestelä-Mielonen,Paula, AU - Isometsä,Erkki, Y1 - 2006/06/15/ PY - 2006/03/28/received PY - 2006/04/21/revised PY - 2006/04/24/accepted PY - 2006/6/20/pubmed PY - 2007/1/19/medline PY - 2006/6/20/entrez SP - 95 EP - 102 JF - Journal of affective disorders JO - J Affect Disord VL - 95 IS - 1-3 N2 - BACKGROUND: Suicidal ideation is likely to represent a phase preceding suicidal acts among most suicidal patients with major depressive disorder (MDD). Factors predicting reversal of the suicidal process are unknown. Our aim was to test the hypothesis that a decline in suicidal ideation is preceded by a decline in hopelessness among patients with MDD. METHOD: Of the 269 Vantaa Depression Study patients with DSM-IV MDD, 103 patients scored > or = 6 points at baseline on the Scale for Suicidal Ideation (SSI). Seventy of these patients were followed-up weekly either until they scored zero points on the SSI, or up to 26 weeks. RESULTS: The median duration for a decline of suicidal ideation to zero was 2.2 months after baseline. The level of baseline suicidal ideation, depressive symptoms, and the presence of any personality disorder predicted duration of suicidal ideation. A decline in both depression (BDI) and hopelessness (HS) independently predicted a decline in suicidal ideation. LIMITATIONS: Due to study design, we do not know if suicidal ideation relapsed after the first time the patient reached zero score in the SSI. CONCLUSIONS: Among patients with major depressive disorder having suicidal ideation, the decline in suicidal ideation is independently predicted by preceding declines in the levels of both depressive symptoms as well as hopelessness. The findings are consistent with possible causal roles of declines in depression and hopelessness in reversing the suicidal process. SN - 0165-0327 UR - https://www.unboundmedicine.com/medline/citation/16780959/Decline_in_suicidal_ideation_among_patients_with_MDD_is_preceded_by_decline_in_depression_and_hopelessness_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-0327(06)00214-X DB - PRIME DP - Unbound Medicine ER -